2. Introduction:
• Pulmonary function tests (PFTs) are a group of
tests that measure how well your lungs works, how
well the lungs take in and exhale air, and how
efficiently they transfer oxygen into the blood.
• PFT or LFT are useful in assessing the functional
status of the respiratory system both in
physiological and pathological condition.
• It is based on the measurement of volumes of air
breathed in and out in normal breathing and forced
breathing.
3. PFT helps to solve many
Respiratory Problems
Make or confirm Diagnosis
Establish a prognosis
Suggest treatment
Monitor effects of treatment
4. Applications of PFT
S.
No.
Applicatio
n
Sub
division
Particulars
I Human
Biology &
Physiology
Physiology Normal Function
Changes with exercise, posture,
barometric pressure, pregnancy etc.
Physiological
Anthropometry
Relation to age , sex, size, ethnic
group, customary activity, variation
→diurnal , seasonal, climatic,
geographical
5. Applications of PFT
S.
No.
Applicatio
n
Sub
division
Particulars
II Clinical
Science
Diagnosis Causes of wheeze, breathlessness,
cyanosis, finger clubbing & aspects of
respiratory failure
Interpretation of abnormal chest X-
ray
Clinical
assessment
Diseases of lung, chest wall, heart &
circulation
Diseases of the central nervous
system
Accident involving the trunk
Medical
Treatment
Oxygen therapy, bronchodilator
therapy, assisted ventilation
6. Applications of PFT
S.
No.
Applicatio
n
Sub
division
Particulars
II Clinical
Science
Surgical
Treatment
Suitability for operation
Anaesthetics Suitability for and management
during & after an anaesthesia
Research
Applications
Evaluation of remedies
Relationship of deranged function to
abnormal structure
Assessment of Prognosis
7. Applications of PFT
S.
No.
Applicatio
n
Sub
division
Particulars
III Community
Medicine
Epidemiology Effects of smoking and air pollution
Prevalence of respiratory impairment
Identification of high risk cases
Rehabilitation Capability for physical work
IV Occupation
al Medicine
Health in
Industry
Pre-employment, periodic & exit
examination, effects of respiratory
hazards, suitability for strenuous work
Establishment of safe conditions
8. Applications of PFT
S.
No.
Applicatio
n
Sub
division
Particulars
IV Occupationa
l Medicine
Diagnosis
and
assessment
of
occupational
pulmonary
diseases
Asbestosis, beryllium disease,
byssinosis, farmers lung,
pneumoconiosis of coal workers and
other occupational groups
Lung disease in grain handlers, hard
metal workers, silo fillers, those
exposed to proteolytic enzymes,
toluene, di-iso-cyanate, etc.
V Medicine &
the Law
Assessment
of disability
Functions of the lungs and the
capacity for exercise
9. 1. Breath holding test:
Ask the patient to take a full but not too deep breath
& hold it as long as possible.
>25 SEC.-NORMAL Cardiopulmonary Reserve
15-25 SEC- LIMITED CardioPulmonary Reserve
<15 SEC- VERY POOR CardioPulmonary Reserve
(Contraindication for elective surgery)
25- 30 SEC - 3500 ml VC
20 – 25 SEC - 3000 ml VC
15 - 20 SEC - 2500 ml VC
10 - 15 SEC - 2000 ml VC
5 - 10 SEC - 1500 ml VC
10. 2. Single Breath Count:
After deep breath, hold it and start
counting till the next breath.
Normal- 30-40 COUNT
Indicates vital capacity
11. 3. SNIDER’S MATCH BLOWING
TEST:
Measures Maximum Breathing Capacity.
Should take 6 attempts
Ask to blow a match stick from a distance of 6”
(15cms) with
Mouth wide open
Chin rested/supported
No pursed lips
No head movement
No air movement in the room
Mouth and match stick at the same level
17. 6. DE BONO’S WHISTLE
BLOWING TEST:
MEASURES PEFR.
Patient blows down a wide bore tube at the
end of which is a whistle, on the side is a
hole with adjustable knob.
As subject blows whistle blows, leak hole
→
is gradually increased till the intensity of
whistle disappears.
At the last position at which the whistle can
be blown, the PEFR can be read off the scale.
19. 7. Wright ‘s Respirometer :
Measures VT and minute volume (MV)
Simple and rapid
Instrument- compact, light and portable.
Disadvantage: It under- reads at low flow
rates and overreads at high flow rates.
Can be connected to endo tracheal tube or
face mask
Prior explanation to patient is needed.
20. Contd…
Ideally done in sitting position.
MV- instrument record for 1 min. And read
directly
VT-calculated and dividing MV by counting
Respiratory Rate.
Accurate measurement in the range of 3.7-
20 L/min.(±10%)
USES: 1) Bedside PFT
2) ICU – Weaning Pts. from Ventilator.
24. Spirometry
• It is an instrument for measuring the air capacity of
the lungs
• Measurement of the pattern of air movement in
and out of the lungs during controlled ventilatory
maneuvers.
• spirometre is used to measure the air flow,
ventilatory regulation, ventilatory mechanics and
lung volume during a forced expiratory maneuver
from full inspiration.
25. INSTRUMENTS
1. Volume Displacement Type
(Dry Rolling Seal Spirometers)
2. Flow Integrating Spirometers
(Use Pneumotachometers)
3. Mechanical Flow Device (Use
Turbine Transducers)
26. Dry Rolling Spirometers
Highest Accuracy and Reproducibility
Accuracy not affected by Humidity
and Temperature
27. Lung volume and capacities
• Lung vol: are the static vol. of air breathed
by an individual, ie vol. of air present in
lung under specific position of the torax
• 4 lung volumes
• Depends on age, weight, gender and body
position
• 2 or more vol. when combined are capacity
28. Lung Volumes
• TV-the vol. of gas exchanged during a
relaxed insp. followed by an exp: (500ml)
• IRV-extra vol: of gas that can be inspired
above tidal insp: 3000ml
• ERV-extra vol: of gas that can be expired
after a normal tidal exp: 1000ml
• RV-vol: of gas remain in lungs after a
forceful exp: 1500ml
29. Lung capacities
• IC-max: amount of gas inspired in to the lungs
after a normal tidal exp: [IC=TV+IRV] 3500ml
• FRC-amount of gas remain in the lungs after
normal exp:[ FRC=ERV+RV] 2500ml
• VC-max: amount of gas expired from the lungs
after a max: insp: [VC=IRV+TV+ ERV] 4500ml
• TLC-max: amount of gas inspired to expand the
lungs to its max:extend [TLC=TV+IRV +ERV
+RV] 6000ml
33. Mechanical Properties
• Compliance
– Describes the stiffness of the lungs
– Change in volume over the change in pressure
• Elastic recoil
– The tendency of the lung to return to it’s resting
state
– A lung that is fully stretched has more elastic
recoil and thus larger/ maximal flows of gas
35. PFT procedure
• Forced expiratory maneuver is the common clinical
approach
• Results are found in patients chart/moniter
• Common spirometric values areFEV1 and FVC
FEV1/FVC ratio
• Lung volume and peak expiratory flow rate (PEF or
PEFR) are measured to differentiate obstructive or
restrictive problems
• Forced expiratory flow (FEF)
36. Procedure
• Sit up straight
• Get a good seal around the mouth piece
• Rapid inhale maximally
• Without any delay blow out as hard as fast as possible
(blast out)
• Continue the exhale until the patient can`t blow no more
• Expiration should continue at least 6sec (in adult) and 3
sec (children under 10yrs)
• Repeat at least 3 technically acceptable times (without
cough, air leak and false start)
38. How to interpret abnormal PFT
• If FVC&FEV1 is less than 80% (total vol:of
air expelling is approx: 80% with in 1sec
ie; FEV1)
• Suggestions of some pathology, at this
point and can`t decide obstructive/
restrictive problem
39. Forced expiratory volume in 1 second
(FEV1)
• FEV1 is the volume of air that can forcibly be
blown out in one second, after full inspiration.
• Average values for FEV1 in healthy people
depend mainly on sex and age height and mass.
• Values between 80% and 120% are considered
normal.
40. Forced vital capacity (FVC)
• Forced vital capacity(FVC) is the volume of
air that can forcibly be blown out after full
inspiration.
41. FEV1/FVC ratio (FEV1%)
• FEV1/FVC (FEV1%) is the ratio of FEV1 to
FVC. In healthy adults this should be
approximately 75–80%.
42. Forced expiratory flow (FEF)
• Forced expiratory flow (FEF) is the flow (or
speed)
of air coming out of the lung during the middle
portion of a forced expiration.
• generally defined by fraction, The usual intervals
are 25%, 50% and 75% (FEF25, FEF50 and
FEF75)
43. Identify an obstructive problem
• Obst: disorders (asthma, copd) air flow reduces
because of narrowing of air ways
• FEV1 is reduced
• Spirogram is continued to 6 sec to empty lung,
FVC also reduced because gas is trapped
behind the obstructed bronchi
• Cardinal feature of obstructive defect is reduction
in the FEV1/FVC ratio
44. Contd…
• In obstructive diseases (asthma, COPD, chronic
bronchitis, emphysema) FEV1 is diminished because
of increased airway resistance to expiratory flow.
• The FVC may be decreased due to the premature
closure of airway in expiration
• This generates a reduced value (<80%, often 45%).
60-80% -mild
40-60% -moderate
<40% -severe obstructions
47. Restrictive problem
• Restrictive disorders can be cause by disease of the lung
parenchyma (lung fibrosis) and chest wall
disease(kyphoscoliosis)
• This prevent the full expansion of the lungs therefore FVC
may be reduced
• FEV1 will increased because of the stiffness of the fibrotic
lungs increases the expiratory pressure
• Hence expired air comes out very quickly resulting with a
high FEV1/FVC ratio