This document discusses the radiological semiotics of diseases of the urinary and genital systems using different imaging modalities including radiography, computed tomography, magnetic resonance imaging, ultrasound, and radionuclide imaging. Key findings that can be seen include stones appearing as opaque densities, tumors appearing as atypical focal masses or densities, cysts appearing as round areas of lower density or signal, and obstructions appearing as filling defects or dilations of organs and ducts. Renal function can be assessed using radionuclide imaging by analyzing the vascular, secretory, and excretory phases of renograms.