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PUPILLARY EVALUATION -DIRECT &
CONSENSUAL LIGHT REFLEX, NEAR
REFLEX TEST, ASSESSMENT OF RAPD
PRESENTER-RAMJI PANDEY
SENIOR CONSULTANT
OPTOMETRIST
1
Anatomy of pupil
Pupil is a aperture located in a center of the iris of the eye
that allows light to strike the retina.
Iris consists mainly of smooth muscle, a circular group
called the sphincter pupillae and a radial group called the
dilater pupillae.
When sphincter pupillae contract the pupil decreases or
constrict the size
The dilater pupillae innervated by sympathetic nerves
from the superior cervical ganglion, cause the pupil to
dilate when they contract of pupil.
2
Rapd
FUNCTION OF THE PUPIL
• Functions:
• Control in retinal Illumination
• Reduction in optical aberration
• Clinical Importance
• Objective indicator of Light Input
• Anisocoria
• Pharmacological Indicator
• Indicator of level of wakefulness
4
VISUAL PATHWAY
• Visual pathway or Optic Pathway is the nervous pathway that
transmits impulses from retina to visual center in cerebral
cortex
• Components
• • Optic Nerve
• • Optic Chiasma
• • Optic Tract
• • Lateral Geniculate Bodies
• • Optic Radiations
• • Visual Cortex
5
CONT….
6
Nasal Fibers decussate in
optic chiasma
Optic tract
Travels centrally along the
optic nerve
Ganglion cells
Rods and
cones
The Accessory motor nuclei
of EW nucleus
New relay fibers partially cross
over
Pretectal Nucleus
Midbrain from Lateral side of
Superior colliculus
Located inferiorly as it enters the
orbit
The axons of the EW nucleus
extend into the III nerve
Lie on the superficial dorsomedial
aspect as it leave the brain stem
Passes laterally to petroclinod
ligament and dorsum sellae
Inferior
division of
III nerve
Ciliary
Ganglion
Via short
Ciliary
nerves
Sphincter
Pupillae
THE LIGHT REFLEX
• The light reflex consist of simultaneous and equal constriction
of pupils in response to stimulation of one eye by light
• Constriction is elicited with extremely low intensities and
is proportional within limits to both intensities and duration of
stimulus.
11
LIGHT REFLEX
• When light is shone in one eye both the pupils constricts.
• Two Types:
• Direct Light Reflex
• Indirect (Consensual) Light Reflex
• Constriction of pupil to which light is shone :
• Direct Light Reflex and that of other : Indirect Light Reflex
12
EXAMINATION OF PUPILLARY
REFLEX
Direct Light Reflex
• Normal pupil reacts briskly & its constriction to light is well
maintained
Consensual Light Reflex
• Normally contralateral pupil should also constrict when light is
thrown on to one pupil
13
LIGHT REFLEX TEST
• What it assess-the integrity of the pupillary light reflex
pathway.
• How to perform it-dim the ambient light and the ask the patient
to fixate a distant target.
• Shine the right eye from right side and left eye from left
side.(Make sure you do not stand infront of the patient as their
pupils will accommodate to focus on you).
• Record whether there is a direct pupillary response (the pupil
constricts when the light is shone on it) and a consensual
response (the fellow pupil constricts too).
• Normal test-there should be a brisk, simultaneous ,equal
response of both pupils in response to light shone in one or the
other eye. 14
NEAR REFLEX
• Two components:
• 1. Convergence Reflex: Convergence of visual axis and
associated constriction of pupil
• 2. Accommodation Reflex: Increased accommodation
and associated constriction of pupil
• Near Reflex Traid consists of:
• - Increased Accommodation
• - Convergence of Visual Axis
• - Constriction of pupils
15
Fibers form Medial Rectus
m. via III n.
Mesencephalic n. of V
nerve
Convergence Center in Tectal
or Pre Tectal Region
EW Nucleus
Efferent fibers travel along
III nerve
Relay in Accessory Ganglion
Sphincter Pupillae
Retina
Via Optic nerve,
Chaisma Optic Tract
Lateral Geniculate
Body,optic radiation
Striate Cortex
From the Para
Striate Cortex
Via Occipitomesencephalic
Tract and Pontine center
EW Nucleus
Via III nerve to
Sphincter Pupillae
NEAR REFLEX TEST
• Instruct the patient to look at the distant target
• The examiner holds up a target containing fine detail
approximately 25cm from the patient
• Ask the patient to fixate the near target and look for pupil
constriction
• Note the speed of the constriction and the roundness of each
pupil
18
AFFERENT PUPILLARY DEFECTS
• Assessment of afferent input from the retina, optic nerve, and
chiasma, optic tract and midbrain till LGB
• Damage anywhere along this portion of the visual pathway
reduces the amplitude of pupil movement in response to a light
stimulus
TOTALAFFERENT PUPILLARY DEFECT
19
• Absence of Direct light reflex on affected side and absence of
consensual light reflex on normal side
•When the normal is stimulated both pupils react normally
• Diffuse illumination both pupils are equal in size
• Near reflex is normal in both eyes
RAPD (Relative Afferent Pupillary Defect)
• Paradoxical response
• Marcus Gunn pupil
• RAPD cause a reduction in pupil contraction when one eye is
stimulated by light compared with when the opposite eye is
stimulated by light.
20
21
GRADING SCALE: RAPD
• Grade 1+: A weak initial pupillary constriction followed by
greater redilation
• Grade 2+: An initial pupillary stall followed by greater
redilation
• Grade 3+: An immediate pupillary dilation
• Grade 4+: No reaction to light – Amaurotic pupil
22
Causes of RAPD
• Optic neuritis
• Anterior ischemic optic neuropathy
• Compressive optic neuropathy
• Glaucoma
• Optic Nerve Tumors
• Orbital Diseases
• Ischemic Retinal Diseases : CRAO CRVO BRAO BRVO
• Ocular Ischemic Syndrome
• CSCR or CME
• RD
• Chiasmal compression
• Optic tract lesion
23
24

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Rapd

  • 1. PUPILLARY EVALUATION -DIRECT & CONSENSUAL LIGHT REFLEX, NEAR REFLEX TEST, ASSESSMENT OF RAPD PRESENTER-RAMJI PANDEY SENIOR CONSULTANT OPTOMETRIST 1
  • 2. Anatomy of pupil Pupil is a aperture located in a center of the iris of the eye that allows light to strike the retina. Iris consists mainly of smooth muscle, a circular group called the sphincter pupillae and a radial group called the dilater pupillae. When sphincter pupillae contract the pupil decreases or constrict the size The dilater pupillae innervated by sympathetic nerves from the superior cervical ganglion, cause the pupil to dilate when they contract of pupil. 2
  • 4. FUNCTION OF THE PUPIL • Functions: • Control in retinal Illumination • Reduction in optical aberration • Clinical Importance • Objective indicator of Light Input • Anisocoria • Pharmacological Indicator • Indicator of level of wakefulness 4
  • 5. VISUAL PATHWAY • Visual pathway or Optic Pathway is the nervous pathway that transmits impulses from retina to visual center in cerebral cortex • Components • • Optic Nerve • • Optic Chiasma • • Optic Tract • • Lateral Geniculate Bodies • • Optic Radiations • • Visual Cortex 5
  • 7. Nasal Fibers decussate in optic chiasma Optic tract Travels centrally along the optic nerve Ganglion cells Rods and cones
  • 8. The Accessory motor nuclei of EW nucleus New relay fibers partially cross over Pretectal Nucleus Midbrain from Lateral side of Superior colliculus
  • 9. Located inferiorly as it enters the orbit The axons of the EW nucleus extend into the III nerve Lie on the superficial dorsomedial aspect as it leave the brain stem Passes laterally to petroclinod ligament and dorsum sellae
  • 10. Inferior division of III nerve Ciliary Ganglion Via short Ciliary nerves Sphincter Pupillae
  • 11. THE LIGHT REFLEX • The light reflex consist of simultaneous and equal constriction of pupils in response to stimulation of one eye by light • Constriction is elicited with extremely low intensities and is proportional within limits to both intensities and duration of stimulus. 11
  • 12. LIGHT REFLEX • When light is shone in one eye both the pupils constricts. • Two Types: • Direct Light Reflex • Indirect (Consensual) Light Reflex • Constriction of pupil to which light is shone : • Direct Light Reflex and that of other : Indirect Light Reflex 12
  • 13. EXAMINATION OF PUPILLARY REFLEX Direct Light Reflex • Normal pupil reacts briskly & its constriction to light is well maintained Consensual Light Reflex • Normally contralateral pupil should also constrict when light is thrown on to one pupil 13
  • 14. LIGHT REFLEX TEST • What it assess-the integrity of the pupillary light reflex pathway. • How to perform it-dim the ambient light and the ask the patient to fixate a distant target. • Shine the right eye from right side and left eye from left side.(Make sure you do not stand infront of the patient as their pupils will accommodate to focus on you). • Record whether there is a direct pupillary response (the pupil constricts when the light is shone on it) and a consensual response (the fellow pupil constricts too). • Normal test-there should be a brisk, simultaneous ,equal response of both pupils in response to light shone in one or the other eye. 14
  • 15. NEAR REFLEX • Two components: • 1. Convergence Reflex: Convergence of visual axis and associated constriction of pupil • 2. Accommodation Reflex: Increased accommodation and associated constriction of pupil • Near Reflex Traid consists of: • - Increased Accommodation • - Convergence of Visual Axis • - Constriction of pupils 15
  • 16. Fibers form Medial Rectus m. via III n. Mesencephalic n. of V nerve Convergence Center in Tectal or Pre Tectal Region EW Nucleus Efferent fibers travel along III nerve Relay in Accessory Ganglion Sphincter Pupillae
  • 17. Retina Via Optic nerve, Chaisma Optic Tract Lateral Geniculate Body,optic radiation Striate Cortex From the Para Striate Cortex Via Occipitomesencephalic Tract and Pontine center EW Nucleus Via III nerve to Sphincter Pupillae
  • 18. NEAR REFLEX TEST • Instruct the patient to look at the distant target • The examiner holds up a target containing fine detail approximately 25cm from the patient • Ask the patient to fixate the near target and look for pupil constriction • Note the speed of the constriction and the roundness of each pupil 18
  • 19. AFFERENT PUPILLARY DEFECTS • Assessment of afferent input from the retina, optic nerve, and chiasma, optic tract and midbrain till LGB • Damage anywhere along this portion of the visual pathway reduces the amplitude of pupil movement in response to a light stimulus TOTALAFFERENT PUPILLARY DEFECT 19 • Absence of Direct light reflex on affected side and absence of consensual light reflex on normal side •When the normal is stimulated both pupils react normally • Diffuse illumination both pupils are equal in size • Near reflex is normal in both eyes
  • 20. RAPD (Relative Afferent Pupillary Defect) • Paradoxical response • Marcus Gunn pupil • RAPD cause a reduction in pupil contraction when one eye is stimulated by light compared with when the opposite eye is stimulated by light. 20
  • 21. 21
  • 22. GRADING SCALE: RAPD • Grade 1+: A weak initial pupillary constriction followed by greater redilation • Grade 2+: An initial pupillary stall followed by greater redilation • Grade 3+: An immediate pupillary dilation • Grade 4+: No reaction to light – Amaurotic pupil 22
  • 23. Causes of RAPD • Optic neuritis • Anterior ischemic optic neuropathy • Compressive optic neuropathy • Glaucoma • Optic Nerve Tumors • Orbital Diseases • Ischemic Retinal Diseases : CRAO CRVO BRAO BRVO • Ocular Ischemic Syndrome • CSCR or CME • RD • Chiasmal compression • Optic tract lesion 23
  • 24. 24