Reabsorption in Loop of Henle
Download as PPTX, PDF1 like1,790 views
The document summarizes reabsorption processes in the proximal convoluted tubule (PCT), thick ascending limb (TAL), and early distal convoluted tubule (DCT). It outlines the objectives of reabsorption of electrolytes and water, the mechanisms involved including passive and active transport, and how medications can alter absorptive processes. Specific reabsorption topics discussed include bicarbonate, the concept of transport maximum, reabsorption in the TAL, calcium reabsorption, and reabsorption in the early DCT.
Reabsorption in Loop of Henle
- 1. REABSORPTION: PCT, THICK ASCENDING LIMB & EARLY DCT Prepared by: Anish Dhakal (Aryan) MBBS Student Patan Academy of Health Sciences
- 2. OBJECTIVES • Reabsorption of important electrolytes and water along the tubule • Mechanisms involved in those reabsorption processes • Mechanisms of alteration of the absorptive processes by some medications
- 3. TRANSPORT MECHANISMS • Passive transport Simple diffusion Facilitated diffusion • Active transport: Primary Active Secondary Active • Protein mediated transport: Symport Antiport
- 5. GENERATION OF THE DRIVING FORCE
- 11. LIMIT OF REABSORPTION: CONCEPT OF TRANSPORT MAXIMUM • Difference between Renal Threshold and Transport Maximum • Introduction of Splay • Classic example is reabsorption of Glucose
- 13. REABSORPTION IN THICK ASCENDING LIMB
- 15. REABSORPTION IN EARLY DCT
- 16. REFERENCES: • Guyton and Hall Textbook of Medical Physiology 13th Edition • BRS Physiology, Linda S Costanzo ,Wolters Kluwer Health • Ganong’s Review of Medical Physiology, 24th Edition