This document discusses responsive web design and compares several frameworks that can be used to implement responsive design. It defines responsive web design and explains its benefits. It then describes four frameworks - Twitter Bootstrap, Foundation, Skeleton, and HTML5 Boilerplate. For each framework, it outlines key features and limitations. It concludes by comparing various aspects of the frameworks, such as grids, plugins, licensing, and recommending Twitter Bootstrap for most use cases due to its balance of features and lightweight code.