This document discusses running GTID replication in production at Gawker Media. It provides an overview of GTID replication and how it works, describes Gawker's replication environment with two data centers, and discusses some common failures encountered with GTID replication including errant transactions, server UUID changes after rebuilds, and "GTID holes" where transactions are missing from slaves. It also covers practical aspects like skipping replication events and using pt-table-checksum for consistency checks.