This document is the teacher's guide for the Grade 10 Science curriculum published by the Department of Education of the Philippines. It provides an overview of the conceptual framework for science education in the K-12 Basic Education Curriculum. The goal is to develop scientific literacy to prepare learners to be informed and engaged citizens. The curriculum covers key concepts in life sciences, physics, chemistry, and earth sciences from Kindergarten through Grade 12. It emphasizes hands-on, inquiry-based learning using various approaches like contextual learning and problem-based learning. The curriculum also aims to develop values like environmental stewardship and innovation. The teacher's guide provides learning modules, activities, and assessments to help teachers implement the Grade 10 science curriculum.