Sustainable development requires multiple transitions across many domains including energy, mobility, food systems, resource use, corporate behavior, governance, knowledge production, lifestyles, and individual mindsets. Achieving sustainability involves balancing economic, social and environmental concerns through complex tradeoffs. Transformative innovation is needed to develop alternative systems, but this faces resistance from incumbent actors and requires changes in both technologies and human values over long periods. Governance must support experimentation while controlling unsustainable practices.