This document summarizes input from an open call on issues regarding the adoption, economic value, standards/governance, privacy/trust, and safety/security of IoT. Some of the key challenges mentioned include the need for transparency to drive adoption, understanding security to properly value it, fragmented standards, balancing privacy and clinical benefits, and restricting technical security approaches due to limited IoT device resources. Providing demonstrators, reducing development costs, and sharing best practices were suggested to help address some of these issues.