This document discusses serial extraction, which is an interceptive orthodontic procedure used to correct hereditary tooth-size discrepancies. It describes when serial extraction should be considered, between ages 6-12, and the criteria for determining if a patient is a suitable candidate. Ideal candidates have a Class I malocclusion with a true tooth-size discrepancy of 10mm or more. Contraindications include Class III maloccusions. A thorough examination and diagnostic records including radiographs and models are required to properly diagnose if serial extraction is appropriate.