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CONTRAINDICATIONS TO
BREASTFEEDING &
ISSUES RELATING TO MATERNAL
MEDICATION
MATERNAL CONTRAINDICATIONS ARE
RARE
 HIV:
 Women known to be HIV infected should be counseled
not to breastfeed. Breastfeeding increases the risk of
transmission of HIV from mother to infant.
 Women at high risk for HIV infection should be counseled
individually regarding the appropriateness of
breastfeeding.
 Women who are not aware of their HIV status should be
informed of the potential benefits for herself and her
infant of knowing her HIV status.
 Women taking antiretroviral medications should not
breastfeed.
MATERNAL
CONTRAINDICATIONS:
INFECTIOUS DISEASE II
2. HTLV-1 (Human T-cell Leukemia Virus Type 1)
 At the current time it is recommended that
women who are HTLV-1 infected should not
breastfeed.
 Studies from Japan indicate that the primary
route of vertical transmission of HTLV-1 is
through breastfeeding.
INFECTIOUS DISEASES
COMPATIBLE WITH
BREASTFEEDING
Breastfeeding may occur in all these cases, although
its initiation may need to be delayed until
mother has undergone treatment.
 Tuberculosis:
 Breastfeeding may be initiated after 2 weeks of maternal therapy.
 Group B Beta-streptococcus and Group A streptococcus
 Mothers infected with these organisms may initiate breastfeeding
after treatment has begun.
INFECTIOUS DISEASES
COMPATIBLE WITH
BREASTFEEDING II
 Hepatitis:
 Hepatitis A: Mother may breastfeed after she
receives gamma globulin
 Hepatitis B: Breastfeeding may begin
immediately after Hepatitis B immunoglobulin
is administered to infant at birth.
 Hepatitis C: Breastfeeding should not be
discouraged unless there is co-infection with
HIV.
INFANT
CONTRAINDICATIONS TO
BREASTFEEDING
 Galactosemia is the only infant condition in which
breastfeeding is contraindicated.
 Galactosemia is an extremely rare enzyme deficiency
(1:50,000 births)
 Use of special formula is required
INFANT
CONTRAINDICATIONS TO
BREASTFEEDING II
 Amino acidurias: combination feeding
is possible, breastfeeding with
supplements of special formula .
 Phenylketonuria (PKU) is the most
common of the amino acid metabolic
disorders.
OTHER INFANT
CONDITIONS
 Breastfeeding is not contraindicated for any
other infant condition.
 Breastfeeding may mask or decrease symptoms
of metabolic disorders.
 Breastfeeding may be medically indicated in
many infant conditions, although it may need to
be supplemented.
RESOURCES FOR
INFECTIOUS DISEASE
INFORMATION
Knowledge about infectious diseases is
constantly evolving. For updates,
contact:
 The Centers for Disease Control
 The American Academy of Pediatrics’
Red Book Committee
GUIDANCE FOR COMMON
POSTPARTUM
EXPERIENCES
 Proactive interventions
providing support at
critical times increase
breastfeeding duration
and exclusivity
MANAGING BREASTFEEDING DURING
CRISES OF CONFIDENCE
 When milk supply concerns arise, always
consider possibility of inadequate milk.
Ask questions and assess for this
problem.
 Assess the milk supply
 Encourage frequent nursing
 Dealing with distractibility: nurse in quiet, dark locations
 nurse at sleepy transition times
 offer feeding before hunger cues are seen
 Assure medical supervision of mother and
baby
FOOD & NUTRITION FOR
BREASTFEEDING MOTHERS
 The Recommended Daily Allowance for
lactating women is 500 additional calories
over pre-pregnant requirement.
 Women consuming less than 1800 kcal/day
may be at risk of low nutrient intake. This
will not change milk composition, but may
deplete mother’s nutrient stores over time.
 Encourage women to follow dietary
guidelines and consume a wide variety of
foods.
FOOD & NUTRITION,
CONT.
 Seek help of a dietitian or nutritionist to provide
dietary guidance to women with special dietary
concerns
 Contrary to myth, there are no foods that should
routinely be forbidden in the diet of nursing
mothers.
FOOD & NUTRITION,
CONT.
 Rarely, breastfed infants may be
sensitive to foreign proteins (such as
cow milk, peanut, etc.) in mother’s
milk. It is not necessary to avoid these
foods unless reaction is suspected.
CONTRACEPTION DURING
LACTATION
 The Lactational Amenorrhea Method (LAM)
 Is a natural, physiological mechanism
 Studies suggest >98% efficacy for LAM as a contraceptive
method when practiced according to protocol
 LAM is reliable as long as the following criteria are met:
 Mother is amenorrheic
 Breastfeeding is exclusive or
nearly exclusive (allows for
vitamins and token foods)
 The infant is less than 6 months
old
CONTRACEPTION, CONT.
 Barrier Methods may be used at any time during
lactation.
 Hormonal Methods
 Use of progestin oral contraceptives, implants and
injectibles is compatible with breastfeeding when
started after 6 weeks postpartum
 Use of combined estrogen-progestin pills is
controversial. Progestin only are the preferred
method.
MATERNAL ILLNESS AND
MEDICATIONS
 If mother has a common illness like a cold, flu or mastitis she
should continue to breastfeed.
 These illnesses are not passed through her milk and
breastfeeding continues to provide protective immunities to
infant.
 Very few maternal medications are contraindicated during
breastfeeding.
MINIMIZING THE IMPACT OF
MATERNAL MEDICATION ON THE
INFANT
 Is drug therapy necessary?
 Consultation between mother’s
prescriber and pediatrician is
advised
 Use the safest drug when a
choice is available
GUIDELINES FOR PRESCRIBING
(HALE)
 Drugs not absorbed through GI tract are
probably safe.
 Choose drugs with lower Milk:Plasma ratios.
High M/P ratios are >1.
 Choose drugs with shorter half-life
 Be cautious of drugs with long pediatric half-lives
 Avoid extended-release formulations
 Choose drugs with higher protein binding
HALE GUIDELINES FOR PRESCRIBING,
CONT.
 Drugs that affect the brain frequently penetrate the
milk in higher levels
 With radioactive compounds, wait 4-5 half-lives
before resuming breastfeeding
 Substances applied to nipple are likely to be ingested
and absorbed by the infant. Do not assume that
topicals are safe.
 Herbal preparations have pharmacological
properties. Do not assume they are safe until
researched fully.
DRUG INFORMATION
RESOURCES
 Hale: Medications and Mother’s Milk
 AAP Drug List
 Briggs, Freeman & Yaffee: Drugs in
Pregnancy & Lactation. Williams & Wilkins
 Drug Information Services:
 The Ruth A Lawrence Poison and Drug
Information Center, Rochester NY
 Rocky Mountain Poison Control
 Dr. Thomas Hale, Texas Tech

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Breastfeeding Module 5: Session 13

  • 1. CONTRAINDICATIONS TO BREASTFEEDING & ISSUES RELATING TO MATERNAL MEDICATION
  • 2. MATERNAL CONTRAINDICATIONS ARE RARE  HIV:  Women known to be HIV infected should be counseled not to breastfeed. Breastfeeding increases the risk of transmission of HIV from mother to infant.  Women at high risk for HIV infection should be counseled individually regarding the appropriateness of breastfeeding.  Women who are not aware of their HIV status should be informed of the potential benefits for herself and her infant of knowing her HIV status.  Women taking antiretroviral medications should not breastfeed.
  • 3. MATERNAL CONTRAINDICATIONS: INFECTIOUS DISEASE II 2. HTLV-1 (Human T-cell Leukemia Virus Type 1)  At the current time it is recommended that women who are HTLV-1 infected should not breastfeed.  Studies from Japan indicate that the primary route of vertical transmission of HTLV-1 is through breastfeeding.
  • 4. INFECTIOUS DISEASES COMPATIBLE WITH BREASTFEEDING Breastfeeding may occur in all these cases, although its initiation may need to be delayed until mother has undergone treatment.  Tuberculosis:  Breastfeeding may be initiated after 2 weeks of maternal therapy.  Group B Beta-streptococcus and Group A streptococcus  Mothers infected with these organisms may initiate breastfeeding after treatment has begun.
  • 5. INFECTIOUS DISEASES COMPATIBLE WITH BREASTFEEDING II  Hepatitis:  Hepatitis A: Mother may breastfeed after she receives gamma globulin  Hepatitis B: Breastfeeding may begin immediately after Hepatitis B immunoglobulin is administered to infant at birth.  Hepatitis C: Breastfeeding should not be discouraged unless there is co-infection with HIV.
  • 6. INFANT CONTRAINDICATIONS TO BREASTFEEDING  Galactosemia is the only infant condition in which breastfeeding is contraindicated.  Galactosemia is an extremely rare enzyme deficiency (1:50,000 births)  Use of special formula is required
  • 7. INFANT CONTRAINDICATIONS TO BREASTFEEDING II  Amino acidurias: combination feeding is possible, breastfeeding with supplements of special formula .  Phenylketonuria (PKU) is the most common of the amino acid metabolic disorders.
  • 8. OTHER INFANT CONDITIONS  Breastfeeding is not contraindicated for any other infant condition.  Breastfeeding may mask or decrease symptoms of metabolic disorders.  Breastfeeding may be medically indicated in many infant conditions, although it may need to be supplemented.
  • 9. RESOURCES FOR INFECTIOUS DISEASE INFORMATION Knowledge about infectious diseases is constantly evolving. For updates, contact:  The Centers for Disease Control  The American Academy of Pediatrics’ Red Book Committee
  • 10. GUIDANCE FOR COMMON POSTPARTUM EXPERIENCES  Proactive interventions providing support at critical times increase breastfeeding duration and exclusivity
  • 11. MANAGING BREASTFEEDING DURING CRISES OF CONFIDENCE  When milk supply concerns arise, always consider possibility of inadequate milk. Ask questions and assess for this problem.  Assess the milk supply  Encourage frequent nursing  Dealing with distractibility: nurse in quiet, dark locations  nurse at sleepy transition times  offer feeding before hunger cues are seen  Assure medical supervision of mother and baby
  • 12. FOOD & NUTRITION FOR BREASTFEEDING MOTHERS  The Recommended Daily Allowance for lactating women is 500 additional calories over pre-pregnant requirement.  Women consuming less than 1800 kcal/day may be at risk of low nutrient intake. This will not change milk composition, but may deplete mother’s nutrient stores over time.  Encourage women to follow dietary guidelines and consume a wide variety of foods.
  • 13. FOOD & NUTRITION, CONT.  Seek help of a dietitian or nutritionist to provide dietary guidance to women with special dietary concerns  Contrary to myth, there are no foods that should routinely be forbidden in the diet of nursing mothers.
  • 14. FOOD & NUTRITION, CONT.  Rarely, breastfed infants may be sensitive to foreign proteins (such as cow milk, peanut, etc.) in mother’s milk. It is not necessary to avoid these foods unless reaction is suspected.
  • 15. CONTRACEPTION DURING LACTATION  The Lactational Amenorrhea Method (LAM)  Is a natural, physiological mechanism  Studies suggest >98% efficacy for LAM as a contraceptive method when practiced according to protocol  LAM is reliable as long as the following criteria are met:  Mother is amenorrheic  Breastfeeding is exclusive or nearly exclusive (allows for vitamins and token foods)  The infant is less than 6 months old
  • 16. CONTRACEPTION, CONT.  Barrier Methods may be used at any time during lactation.  Hormonal Methods  Use of progestin oral contraceptives, implants and injectibles is compatible with breastfeeding when started after 6 weeks postpartum  Use of combined estrogen-progestin pills is controversial. Progestin only are the preferred method.
  • 17. MATERNAL ILLNESS AND MEDICATIONS  If mother has a common illness like a cold, flu or mastitis she should continue to breastfeed.  These illnesses are not passed through her milk and breastfeeding continues to provide protective immunities to infant.  Very few maternal medications are contraindicated during breastfeeding.
  • 18. MINIMIZING THE IMPACT OF MATERNAL MEDICATION ON THE INFANT  Is drug therapy necessary?  Consultation between mother’s prescriber and pediatrician is advised  Use the safest drug when a choice is available
  • 19. GUIDELINES FOR PRESCRIBING (HALE)  Drugs not absorbed through GI tract are probably safe.  Choose drugs with lower Milk:Plasma ratios. High M/P ratios are >1.  Choose drugs with shorter half-life  Be cautious of drugs with long pediatric half-lives  Avoid extended-release formulations  Choose drugs with higher protein binding
  • 20. HALE GUIDELINES FOR PRESCRIBING, CONT.  Drugs that affect the brain frequently penetrate the milk in higher levels  With radioactive compounds, wait 4-5 half-lives before resuming breastfeeding  Substances applied to nipple are likely to be ingested and absorbed by the infant. Do not assume that topicals are safe.  Herbal preparations have pharmacological properties. Do not assume they are safe until researched fully.
  • 21. DRUG INFORMATION RESOURCES  Hale: Medications and Mother’s Milk  AAP Drug List  Briggs, Freeman & Yaffee: Drugs in Pregnancy & Lactation. Williams & Wilkins  Drug Information Services:  The Ruth A Lawrence Poison and Drug Information Center, Rochester NY  Rocky Mountain Poison Control  Dr. Thomas Hale, Texas Tech