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Drug-Coated Balloon Coronary Angioplasty
Versus Stenting for Treatment of Disease
Adjacent to a Chronic Total Occlusion.
Co-CTO Trial
NCT04881812
Alexander Nap
Amsterdam UMC
Netherlands
I, Alexander Nap DO NOT have a financial
interest/arrangement or affiliation with one or more
organizations that could be perceived as a real or
apparent conflict of interest in the context of
the subject of this presentation
Disclosure Statement of Financial Interest
SIZEDOES MATTER!
Claessen et al. JACC Interv 2011
MACE
length
diameter
DCB?
Courtesy B.BRAUN
WHY USE DCB?
BASKET-2-SMALL
DEBUT
Rissanen et al. Lancet 2019, Jeger et al. Lancet 2018
minimize DES burden (MACE, PHYSIOLOGY, CABG)
WHEN USE DCB?
Jeger et al. JACC Interv 2020
WHEN USE DCB?
Shin et al. JACC Interv 2023
WHEN USE DCB?
Shin et al. JACC Interv 2023
Session X: “Ongoing CTO Trials” DCB vs. DES in CTO A. Nap, Netherlands
DCB IN CTO?
Walsh et al. JACC Interv 2020
Co-CTO - NCT04881812
pPCI
DIAMETER STENOSIS
(GAIN)
1 Y
DIAMETER STENOSIS
LATE LUMINAL LOSS
RE-OCCLUSION
MACE
DCB CTO ONLY?
Terashita et al. Cath Cardiovasc Interv 2023

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Session X: “Ongoing CTO Trials” DCB vs. DES in CTO A. Nap, Netherlands