Shahid Bashir_ H K CV update
- 1. 1 Curriculum Vitae Name: Shahid Bashir Office Address: Berenson-Allen Center for Noninvasive Brain Stimulation Harvard Medical School 330 Brookline Avenue, Kirstein Building, Room KS158 Boston, MA 02215 United States Office Address: Department of physiology, Faculty of Medicine King Saud University, P O Box 2925, Riyadh 11461 Saudi Arabia Work Email: sbashir@bidmc.harvard.edu sbashir10@gmail.com Work FAX: 617-975-5322 Place of Birth: Lahore, Pakistan Position 1. 2011-present: Department of physiology, Faculty of Medicine King Saud University, P O Box 2925, Riyadh 11461 Saudi Arabia. 2. 2010-present: Instructor of Harvard Medical 330 Brookline Avenue, Kirstein Building, Room KS158 Boston, MA 02215 United States. Education 1998 B.Sc. Chemistry and Biology Univ. of Punjab Lahore, Pakistan 2001 M.Sc. Biology Univ. of Punjab Lahore, Pakistan 2007 Ph.D. Physiology Univ. of Fribourg Fribourg, Switzerland Postdoctoral Training 2007 - 2008 Postdoctoral Fellow Neurophysiology Univ. of Fribourg Fribourg, Switzerland 2008 - 2010 Research Fellow Neurology Harvard University Boston, MA Other Professional Positions 2003 - 2006 Visiting Fellow CHUV Hospital, University of Lausanne, Switzerland 2006 Visiting Trainee University of Bern, Department of Medicine, Switzerland 2007 Visiting Trainee Universtiy of Zurich, Department of Neurobiology, Switzerland
- 2. 2 Professional Societies 2004-present Swiss Society of Neuroscience Member 2004-present Federation European Neuroscience Society Member Honors and Prizes 2000 Presidential fellowship for talent student Pakistan Higher education Fellowship 2007 Travel Grant Swiss Society of Neuroscience Grant Review Activities 2012-present International Grant Review Committee Human Frontier Science Program 2012- present International Grant Review Committee Italian Research Council 2013-present International Grant Review Committee Austrillain Science Commission 2013-present International Grant Review Committee Human brain project Europe 2014-present International Grant Review Committee KACST Editorial Activities Reviewer most major journals in the felds of neurology, neuroscience, psychiatry, neurophysiology, including for example: Behavioral and Brain Sciences; Clinical Neurophysiology; Journal of International Neuroscience; Basic and Clinical Neuroscience, Pakistan journal of Medical Science, Journals of Arts and Education, Neurology, Psychiatry and Brain Research, Science and Education Publishing, Saudi Neuroscience etc Course 2007 Introductory Course in Laboratory Animal Sciecne University of Zurich 2008 Intensive Course in Transcranial Magnetic Stimulation Harvard Medical school 2010 Postgraduate Education Program in Clinical & Translational Science Harvard Medical school 2012 Leadership Strategies for the Researcher Harvard Medical school 2012 Design and Implementation of Clinical Trials Harvard Medical school 2010 Principles and Practice of Clinical Research course Harvard Medical school 2011 Review of Neurology Harvard Medical school 2006 New techniques in Lab animal Sciecne University of Fribourg 2013 Dementia Harvard Medical school 2013 The Science of Placebo Harvard Medical school 2013 The Blackburn Course in Obesity Medicine: the Practical Clinical Approaches and Board BIDMC
- 3. 3 Review 2006 Basic Life Support BIDMC 2011-2013 CITI Collaborative Institutional Training Initiative BIDMC 2011 Open Workshop on Technology and Autism Research MIT Media Lab, 2011 Novel Statistical Methods for Investigating Aging and Cognitive Decline Harvard School of Public Health 2011 Molecules, Movement, and Motors Science Symposium Radcliffe Gymnasium 2011 Workshop on Gene-Environment Interactions, Broad Institute, 7 Cambridge Center 2010 Mayo Clinic CTSA Exercise Science Symposium Mayo Clinic 2015 Core Education Curriculum Harvard Medical school 2014 TREATING EATING DISORDERS Harvard Medical school 2014 Longwood Neurology Harvard Medical school 2014 Intensive Review of Neurology Harvard Medical school 2014 Child Neurology Course Harvard Medical school 2014 Eating Disorders Harvard Medical school 2015 CANTAB training and application KSU, College of Medicine, Saudi Arabia 2015 Reviving Learning Management System KSU, College of Medicine, Saudi Arabia Report of Funded and Unfunded Projects Present 2015-2017 King Abdulaziz City for Science and Technology (Apporaved) To develop a safe, inexpensive and noninvasive biomarker of epileptogenesis after Traumatic Brain Injury Principle Investigator 2015-2017 King Abdulaziz City for Science and Technology (Apporaved) Neurophysiological measures as end-point in multiple sclerosis clinical trials: the use of Transcranial Magnetic Stimulation. Co-Investigator 2015-2017 King Abdulaziz City for Science and Technology (Apporaved) Effects of navigated transcranial magnetic stimulation priming with transcranial DC stimulation coupled with constraint-induced movement therapy on the motor function of stroke patients in the Kingdom of Saudi Arabia. Co-Investigator 2014-2016 Deanship of King Saud University (Apporaved)
- 4. 4 Brain plasticity (International research group) award Principle Investigator 2014-2016 Deanship of King Saud University (Apporaved) Eraly neurophysiological marker for brain disability (international research group) award. Principle Investigator 2013-2016 King Abdulaziz City for Science and Technology (Apporaved) Study the neural controls of emotional resonance and develop a novel intervention approach to improve emotional resonance in Autism Spectrum Disorder Principle Investigator 2013-2016 National Plane for Sciecne and Technology (Apporaved) Testing causality in the association between exercise and neurocognitive gains: a pioneer translational research study in Kingdom of Saudi Arabia Principle Investigator 2013-2016 Deanship of King Saud University (Apporaved) Spritulity and fMRI Principle Investigator 2013-2016 King Abdulaziz City for Science and Technology (Apporaved) Prefrontal cortex modulation with transcranial direct current stimulation (tDCS) for nicotine craving reduction: A double blind, sham-controlled study. Principle Investigator Past 2003-2006 Fellowship from University of Fribourg. Rehabilitation of stroke and cerebellar patients Study design, recorded and analysis data on stroke and Cerbeller patients populations (part od thesies work) 2003-2008 Novartis Spontaneous functional recovery of manual dexterity resulting from a lesion of the motor cortex treated with neurite outgrowth inhibitor Nogo-A in primates Co-investigator Recorded and analyzed neurophysiologic activity from motor cortex treated with neurite outgrowth inhibitor Nogo-A in primates 2008-2011 National Institutes of Health, National Institute for Deafness and Communication Disorders, RO1-DC05672 Transcranial Magnetic Stimulation to Improve Speech Co-Investigator
- 5. 5 Examine the potential use of repetitive transcranial magnetic stimulation as therapy for non-fluent aphasia 2009-2011 International Brain Research Foundation Promoting Recovery from Traumatic Brain Injury Co-Investigator To test cortico-cortical connectivity, plasticity and network dynamics using the real-time combination of transcranial magnetic stimulation and electroencephalography (EEG) as a predictor of recovery from mild TBI 2010 – 2011 CIMIT Characterization of Cortical Plasticity after Mild Traumatic Brain Injury in Humans Co-Investigator To test cortico-cortical connectivity, plasticity and network dynamics using the real-time combination of transcranial magnetic stimulation and electroencephalography (EEG) Current Unfunded Projects 2016 - 2018 National Institutes of Health (R21 under review) Noninvasive, Physiologic Characterization of Cortical Plasticity after Mild Traumatic Brain Injury in Humans Co-Investigator To test cortico-cortical connectivity, plasticity and network dynamics using the real-time combination of transcranial magnetic stimulation and electroencephalography (EEG) in Mild Traumatic Brain Injury patients 2016 - 2018 National Plane for Sciecne and Technology (under review) Pioneer study about age related alteration in brain plasticity may predict the risk for dementia in Kingdom of Saudi Arabia Principle Investigator To test cortico-cortical connectivity, plasticity and network dynamics using the real-time combination of transcranial magnetic stimulation and electroencephalography (EEG) in AD patients 2016 - 2018 National Plane for Sciecne and Technology (under review) Effects of navigated transcranial magnetic stimulation prime with transcranial DC stimulation coupled with constraint induced movement therapy on motor function in stroke patients (pioneer rehabilition study in kingdom of Saudi Arabia Principle Investigator To test how TMS prime with tDCS and physical activity enhance brain plasticity and improved motor related problem in upper extermitity in stroke patients Report of Local Teaching and Training
- 6. 6 Teaching of Students in Courses 2003 - 2007 Practical course for Second year medical students (Neurophysiology), ~50 students Three hours per day for three weeks University of Fribourg 2008 – 2013 Intensive Course in Transcranial Magnetic Stimulation. ~10 to 15 students per course. 9 hours preparation and contact time per course (three courses a year). Harvard Medical school 2014 – 2014- 2014- 2015 CNS course, College of Medicine CNS course, College of Pharmacy CNS course, College of Dentistry Research Methdology (Post graduate) King Saud University King Saud University King Saud University King Saud University Local Invited Presentations 2008 Poststroke Rehabilitation, Invited Lecturer BIDMC, Neurology Report of Regional, National and International Invited Teaching and Presentations Invited Presentations and Courses International 2007 Poststroke Rehabilitation in Pakistan” Seminar, Invited Speaker University of health science, Department of Physiology, Lahore, Pakistan 2013 Appilacation of Brain stimulation in Basic and Clinical Neuroscience, Kign Fahad Speclist Hospital, Damma, Saudi Arbia 2012 Appilacation of Brain stimulation in Basic and Clinical Neuroscience, King Abudaziz University, Jedah, Saudi Arbia 2013 Appilacation of Brain stimulation in Autism, Beterji Medical School, Jedah, Saudi Arbia 2015 “CANTAB training and application, KSU, Saudi Arbia 2015 5th Annual Saudi Epilepsy & 1st GCC Epilepsy Congress in Dammam from 5thnd to 7th November 2015, KSU, Saudi Arbia 2016 Appilacation of tDCS in Clinical Neuroscience IBRO/APRC Neuroscience School, Nagarkot, Kathmandu, Nepal 2016 Appilacation of tDCS in Basic Neuroscience. Neuroscience Society of Nepal, Nagarkot, Kathmandu, Nepal 2016 Clinical applications of Transcranial direct current stimulation: Must they start or should they still watch in developed and Underdeveloped countries? Pakistan Society of Neurology, Islamabad , Pakistan Technical skills
- 7. 7 Noninvasive brain stimulation technique: single pulse, high and low frequency repetitive Transcranial Magnetic Stimulation, frameless stereotactic neuronavigation to locate brain areas, electromyography, EEG and behavioural tasks. Current Pre-doctoral Students/Coop Students/Research Assistants 2010-2011 Frederick Ifert-Miller / Research Assistant 2010-2011 Ilan Mizrahi-Arnaud / Medical Student, Boston University 2010-2011 Syed Faaiz Enam / Medical Student, Agh Khan Medical University, Pakistan 2009-2011 Anuhya Capia / Medical Student, Boston University 2013-2014 Mohammed ALARABI/ Medical Student, King Saud University 2013-2015 Rana Zein/ Medical Student, King Saud University 2014-2015 Faisal AlGhamdi / Medical Student, King Saud University 2014-2015 Sara/ Medical Student, King Saud University 2015-present Abdullah Ahmed Alatawi / Medical Student, King Saud University 2015-present Tariq Sami Almusned / Medical Student, King Saud University 2015-present Ahmed Hussien Alhussien / Medical Student, King Saud University 2015-present Meshal Abdulhameed Alohali / Medical Student, King Saud University 2015-present Mohammed ALQuwayee / Medical Student, King Saud University 2015-present Abdullah bin Jurays / Medical Student, King Saud University 2015-present Muhannad ALWabel / Medical Student, King Saud University 2015-present Fars ALManie / Medical Student, King Saud University 2015-present Tariq ALMatrodi / Medical Student, King Saud University 2015-present Abdulrahman Al-Thaqib / Medical Student, King Saud University 2015-present Fahad Al-Qahtani / Medical Student, King Saud University 2015-present Abdullah Al-Zahrani / Medical Student, King Saud University 2015-present Fahad Al-Sultan / Medical Student, King Saud University 2015-present Mish'al Alfallaj/ Medical Student, King Saud University 2015-present Abdulaziz Alahmari/ Medical Student, King Saud University 2015-present Abdullah Almazyad/ Medical Student, King Saud University 2015-present Abdulmajeed Abdulrahman / Medical Student, King Saud University 2015-present Talal alsaeed/ Medical Student, King Saud University 2015-present Ghadah Maher Abdulaziz / Medical Student, King Saud University 2015-present Rawan Abdulaalah Alyahya / Medical Student, King Saud University 2015-present Dahna Sultan Alkahtani / Medical Student, King Saud University 2015-present Noura Abdulmunim Alrayes / Medical Student, King Saud University
- 8. 8 2015-present Sarah Saad Alangari / Medical Student, King Saud University 2015-present Ghadeer Khaled Alzahrani / Medical Student, King Saud University 2015-present Majid Abdullah/ Medical Student, King Saud University Publications Peer reviewed publications in print or other media 1. Shahid Bashir, Marine Varnet, Umer Najib, Jennifer Perez, Miguel Alonso-Alonso, Mark Knobel, Woo-Kyoung Yoo, Dylan Edwards, Alvaro Pascual-Leone. 2016. Enhanced motor function and its neurophysiological correlates after navigated low-frequency repetitive transcranial magnetic stimulation over the contralesional motor cortex in stroke. Restorative neurology and neuroscience. 2. Shahid Bashir, and Woo-Kyoung Yoo. 2016. Neuromodulation for addiction by transcranial direct current stimulation: opportunities and challenges. Annals of neuroscience. 3. Túnez I. Escribano BM, Santamaría A, De Lima ME, Bashir S. 2016. Brain magnetic stimulation in animal models: a valuable lesson for clinical applications. CNS Neurol Disord Drug Targets. 4. Abdulrahman M Alsharidah, Ghulam Murtaza, Muhannad M Alsharidah, Shahid Bashir. 2016. Fasting in Ramadan Affects Cognitive and Physiological Function in Normal Subjects (Pilot Study). Neuroscience & Medicine 5. BM Escribano, A Santamaría, ME De Lima, M De Lima, S Bashir, I Túnez, SK Tayebati, D Tomassoni, F Amenta. 2016. Neuroinflammatory markers in spontaneously hypertensive rat brain: an immunohistochemical study. CNS & neurological disorders drug targets. 6. Mohammed Alarabi, Abdullah Al-Turki, Mohammed Mahasin, Abdulrahman Al-Sehly, Faisal Al-Dawood, Saleh Al-Kurini, Shahid Bashir. 2016. Cognitive function and its association with level of education and work status in adults in Saudi Arabia: a cross-sectional study. International Journal of Research in Medical Sciences. 7. Bilaal Ahmed, Syed Faaiz Enam, Shahid Bashir. (2016): Depression and Anxiety: A Snapshot of the Situation in Pakistan. Journal of research in Medical science. 8. Dost Muhammad Halepoto, Shahid Bashir, Rana Zeina, Laila Y Al-Ayadhi. 2016. Correlation Between Hedgehog (Hh) Protein Family and Brain-Derived Neurotrophic Factor (BDNF) in Autism Spectrum Disorder (ASD). Journal of the College of Physicians and Surgeons--Pakistan: JCPSP 24. 9. Dost Muhammad Halepoto, Shahid Bashir, Rana Zeina, Laila Y Al-Ayadhi. 2016. Correlation Between Hedgehog (Hh) Protein Family and Brain-Derived Neurotrophic Factor (BDNF) in Autism Spectrum Disorder (ASD). Journal of the College of Physicians and Surgeons--Pakistan: JCPSP 24. 10. Lindsay M Oberman, Fritz Ifert-Miller, Umer Najib, Shahid Bashir, Joseph Gonzalez Heydrich, Jonathan Picker, Alexander Rotenberg, Alvaro Pascual-Leone. 2016. Abnormal Mechanisms of Plasticity and Metaplasticity in Autism Spectrum Disorders and Fragile X Syndrome. Journal of child and adolescent psychopharmacology 11. Abdulrahman M. Alsharidah, Ghulam Murtaza, Muhannad M. Alsharidah, Shahid Bashir. Fasting in Ramadan Affects Cognitive and Physiological Function in Normal Subjects (Pilot Study). Neuroscience & Medicine, 2016, 7, 12. Shahid Bashir, Marine Vernet, Umer Najib, Jennifer Perez, Miguel Alonso-Alonso, Mark Knobel, Woo-Kyoung Yoo, Dylan Edwards, Alvaro Pascual-Leone (2015). Enhanced motor
- 9. 9 function and neurophysiological correlates with navigated low-frequency repetitive transcranial magnetic stimulation over the contralesional motor cortex in stroke. Brain Stimulation, 2015. 13. K Jung, A Jun, Y Kim, S Bashir, SH Ohn (2015). DTI Findings Correlated with Neurocognitive Impairments in Basal Ganglia Stroke: A Preliminary Study. J Neurol Neurophysiol (299-2). 14. Rana Zeina, AL-Ayadhi Laila, Shahid Bashir (2015). The Impact of IQ on Using High-tech Augmentative Alternative Communication AAC in Children with Autism Spectrum Disorder ASD. Procedia-Social and Behavioral Sciences (366-373). 15. Sara Tremblay, Marine Vernet, Shahid Bashir, Alvaro Pascual-Leone, Hugo Théoret (2015). Theta burst stimulation to characterize changes in brain plasticity following mild traumatic brain injury: A proof-of-principle study. Restorative neurology and neuroscience. 16. Muhammad Iqbal, Shahid Bashir, Laila Al-Ayadhi (2015). Prevalence of antimitochondrial antibodies in autism spectrum subjects. Future Neurology (203-209). 17. Shahid Bashir, Laila AL-Ayadhi (2015). Endothelial antibody levels in the sera of children with autism spectrum disorders. Journal of the Chinese Medical Association (414-417). 18. Shahid Bashir, Rana Zeina, Dost Muhammad, Laila Al-Ayadhi (2014). Role of hedgehog protein family members in autistic children. Neurology, Psychiatry and Brain Research (63-67). 19. Shahid Bashir (2014). Novel Approaches of Non-Invasive Stimulation Techniques to Motor Rehabilitation Following Stroke: A Review. Brain & Neurorehabilitation (71-75). 20. Shahid Bashir, Laila AL-Ayadhi (2014). Alterations in plasma dipeptidyl peptidase IV in autism: A pilot study. Neurology, Psychiatry and Brain Research 20 (2), 41-44. 21. DM Halepoto, S Bashir, L Al-Ayadhi (2014). Possible role of brain-derived neurotrophic factor (BDNF) in autism spectrum disorder: current status. Journal of the College of Physicians and Surgeons--Pakistan: JCPSP 24. 22. S Bashir, LY Al-Ayadhi. (2013). Effect of camel milk on thymus and activation-regulated chemokine in autistic children: double-blind study. Pediatric research 75 (4), 559-563. 23. Shahid Bashir, and Laila AL-Ayadhi. (2013): Role of serum levels of neurotensin in children with autism spectrum disorder. Neurology, Psychiatry and Brain Research. Volume 19, Issue 2, June 2013, Pages 59–63. 24. Bashir S, Perez J, Jared, H and Pascual-Leone A. (2012): Differentiation of motor cortical representation of hand muscles by navigated mapping of optimal TMS current directions in healthy subjects. ID no. JCNP-D-12-00002. Journal of Clinical Neurophysiology, 2013. 25. S Bashir, WK Yoo. Cheap Technology Like Transcrinal Direct Current Stimulation (tDCS) Could Help in Stroke Rehabilitation in South Asia. - Basic and Clinical Neuroscience, 2013. 26. Marine Vernet, Shahid Bashir, Woo-Kyoung Yoo, Lindsay Oberman, Ilan Mizrahi, Frederick Ifert-Miller, Charles J Beck, Alvaro Pascual-Leone. Reproducibility of the effects of theta burst stimulation on motor cortical plasticity in healthy participants. Clinical Neurophysiology, 2013. 27. Marine VERNET, Shahid BASHIR, Woo-Kyoung YOO, Jennifer M. PEREZ, Umer NAJIB, Alvaro PASCUAL-LEONE. Motor plasticity induced by theta burst stimulation: correlated measures of MEPs and EEG in young versus old health individuals. Eur J Neurosci. 2012 Nov 28. PMID: 23190020 28. Shahid Bashir. Hope and great opportunity for young neuroscientist. Pakistan Journal of Medical Sciences. 2013. 29. Shahid Bashir, Fawaz Abdulaziz Al-Hussain and Woo-Kyoung Yoo, Neural Plasticity and Hemispatial Neglect in Stroke. Journal of Pakistan Medical Associattion, 2013. 30. S Bashir, DM Halepoto, L Al-A. Serum Level of Desert Hedgehog Protein in Autism Spectrum Disorder: Preliminary Results. S Bashir, DM Halepoto, L Al-Ayadhi - Medical Principles and Practice, 2013.
- 10. 10 31. Shahid Bashir, and Laila AL-Ayadhi. (2012): Indian Hedgehog Protein Levels In Autistic Children: Preliminary results. J Mol Biomark Diagn, 2012. http://dx.doi.org/10.4172/2155- 9929.1000134 32. Vanessa Krause, Shahid Bashir, Bettina Pollok, Anuhya Capia, Alfons Schnitzler & Alvaro Pascual-Leone. (2012): 1 Hz rTMS of the left posterior parietal cortex (PPC) improves sensorimotor timing. J. Neuropsychologia. PMID: 23103789 33. Shahid BASHIR, Marine VARNET, Woo-Kyoung YOO, Ilan MIZRAHI, Hugo THEORET and Alvaro PASCUAL-LEONE. (2012): Changes in Cortical Plasticity After Mild Traumatic Brain Injury. J. Restorative Neurology and Neuroscience. PMID: 22596356 34. Marianne Anke S, Sylvie K, Jérôme P, Shahid B, Thomas F, Dieter Georg R, Karin D. Effect of long-term climbing training on cerebellar ataxia: a case series. Rehabil Res Pract. 2011;2011:525879. PMID: 22191034 35. Freitas C, Perez J, Knobel M, Tormos JM, Oberman L, Eldaief M, Bashir S, Vernet M, Peña- Gómez C, Pascual-Leone A. Changes in cortical plasticity across the lifespan. Front Aging Neurosci. 2011; 3:5. PMID: 21519394 36. Bashir S, Kaeser M, Wyss A, Hamadjida A, Liu Y, Bloch J, Brunet JF, Belhaj-Saif A, Rouiller EM. Short-term effects of unilateral lesion of the primary motor cortex (M1) on ipsilesional hand dexterity in adult macaque monkeys. Brain Struct Funct. 2011 May 20. PMID: 21597965 37. Stamoulis S, Oberman L, Praeg E, Bashir S, Pascual-Leone A (2011): Single Pulse TMS- Induced Modulations of Resting Brain Neurodynamics Encoded in EEG Phase. Brain Topogr. PMID: 21203817 38. Bashir S, Edwards D, and Pascual-Leone A (2010): Neuro-navigation increases the effectiveness of low-frequency rTMS on primary motor cortex in healthy subjects. Brain Topogr. PMID: 21076861 39. Oberman L, Ifert-Miller F, Najib U, Bashir S, Woollacott I, Gonzalez-Heydrich J, Picker J, Rotenberg A and Pascual-Leone A (2010): Transcranial magnetic stimulation provides means to assess cortical plasticity and excitability in humans with fragile X syndrome and autism spectrum disorder. Front. Syn. Neurosci. 2:26. PMID: 21423512 40. Kaeser M, Wyss A, Bashir S, Hamadjida A, Liu Y, Bloch J, Brunet JF, Saif AB and Rouiller EM (2010): Long-Term effects of Unilateral Lesion of the Primary Motor Cortex (M1) on Ipsilesional Hand Dexterity in Adult Macaque Monkeys: relationship with functional recovery of the contralesional hand. J Neurophysiol. 103(3):1630-45. PMID: 20071636 41. Stamoulis C, Praeg E, Bashir S, Chang BS, Pascual-Leone A (2009): Estimation of Brain State Changes Associated with Behavior, Stimulation and Epilepsy. Conf Proc IEEE Eng Med Biol Soc. 4719-22. PMID: 19964837 42. Diserens K , Herrmann F , Perret N , Chatelain S , Filipovic N , Bashir S , Ruegg D , Vuadens, P , Bogousslavsky J , Vingerhoets F (2007): The effect of repetitive arm cycling on post stroke spasticity and motor control. J Neurol Sci. 15; 253(1-2):18-24. PMID: 17241642 43. Zaheer A, Akhtar T and Bashir S (1999): Echinoucus granulosus, histopathology of naturally infected sheep liver. Punjab univ.j.zool. Vol. No. 14. 105-111. Record number: PK2001001205 44. Naeser MA, Martin P, Ho M, Treglia E, Kaplan E, Bhashir S, Pascual-Leone A (2011): Transcranial Magnetic Stimulation and Aphasia Rehabilitation. Article for Summer Supplement, on Language-based Disorders in Rehabilitation For Archives of Physical Medicine and Rehabilitation. PMID: 22202188 45. Pascual-Leone A, Freitas C, Oberman L, Horvath JC, Halko M, Eldaief M, Bashir S, Vernet M, Shafi M, Westover B, Vahabzadeh-Hagh AM, Rotenberg A. Characterizing Brain Cortical Plasticity and Network Dynamics Across the Age-Span in Health and Disease with TMS-EEG and TMS-fMRI. Brain Topogr. 2011 Aug 14. PMID: 21842407
- 11. 11 46. Najib U, Bashir S, Edwards D, Rotenberg A, Pascual-Leone A (2011): Transcranial Brain Stimulation: Clinical Applications and Future Directions. Neurosurgery Clinics of North America. PMID: 21435574 47. Bashir S , Mizrahi I , Weaver K , Fregni F, Pascual-Leone A (2010): Assessment and modulation of neuroplasticity in rehabilitation with transcranial magnetic stimulation. Physical Medicine and Rehabilitation. 2 (12) Supplement: S253-S268. PMID: 21172687. 48. Naeser MA, Martin PI, Treglia E, Ho M, Kaplan E, Bashir S, Hamilton R, Coslett HB, Pascual- Leone A (2010): Research with rTMS in the treatment of aphasia. Restor Neurol Neurosci. 28 (4):511-29. PMID: 20714075. 49. Ekhtiari H and Bashir S (2010): Brain Stimulation Technology in Addiction Medicine; Main Problems Waiting for Solutions. Basic And Clinical Neuroscience. 1(4): 3-4. BCN 1389 http://bcn.iums.ac.ir/browse.php?a_code=A-10-1-37&slc_lang=en&sid=1 50. Bashir S, Sikaroudi H, Kazemi R and Ekhtiari H (2010): Integrated technologies like noninvasive brain stimulation (NIBS) for evaluation in rehabilitation in stroke; New hopes for patients, neuroscientists, and clinicians in Iran. Basic And Clinical Neuroscience. 1(4): 6-14; BCN 1389. http://bcn.iums.ac.ir/browse.php?a_code=A-10-1-38&slc_lang=en&sid=1 Thesis Bashir S (2007): Rehabilitation of stroke and cerebellar patients. Fribourg, Switzerland: University of Fribourg, Department physiology. http://ethesis.unifr.ch/theses/downloads.php?file=BashirS.pdf Abstracts, Poster Presentations and Exhibits Presented at Professional Meetings 1. Bashir S and Dieter R. Estimation of the input-force relation of a muscle by superposition of contraction. The Annual Meeting of the Swiss Society for Neuroscience (2003), Fribourg, Switzerland. 2. Bashir S and Dieter R. The effect of gravity and negative pressure in the lower body on cycling. USGEB meeting (2004) Fribourg, Switzerland. 3. Bashir S, Kaeser M, Beaud ML, Freund P, Wyss A, Belhaj-Saif A, Bloch J, Debatisse D, Mir A, Pralong E, Rouiller E and Wannier T. Characterization of early somatosensory evoked potentials (SEPs) to electrical stimulation of the median nerve in adult macaque monkeys: intact and spinal lesioned animals. Society of Neuroscience (2007), 37th annual meeting, San Diego, CA 4. Bashir S, Kaeser M, Beaud ML, Freund P, Wyss A, Belhaj-Saif A, Bloch J, Debatisse D, Mir A, Pralong E, Rouiller E and Wannier T. Effects of a combination of ketamine and medetomidine hydrochloride (KM) anaesthesia on somatosensory evoked potentials (SEPs) obtained by electrical stimulation of the median nerve in macaque monkeys. The Annual Meeting of the Swiss Society for Neuroscience (2007) Bern, Switzerland. 5. Naeser MA, Martin P, Treglia E, Ho M, Baker E, Kaplan E, Bashir S, Pascual-Leone A. Improved Action Naming in a Severe, Nonfluent Aphasia Patient following Transcranial Magnetic Stimulation plus Constraint-Induced Language Therapy. Academy of Aphasia 47th Annual Meeting. (2009), Boston, MA. 6. Eric S, Adjia H, Joël B, Bashir S, Belhaj-Saïf A, Rouiller E and Henri-Marcel H. Effect of Anti Nogo-A antibody treatment on cortical lesion of the motor cortex of macaque monkeys assessed on
- 12. 12 Magnetic Resonance Imagery (MRI). The Annual Meeting of the Swiss Society for Neuroscience (2009), Fribourg, Switzerland. 7. Rouiller E , Kaeser M, Wyss A, Hamadjida A, Bashir S, Liu Y, Bloch J, Brunet Jean-F and Belhaj- Saïf A. Role of the primary motor cortex (M1) in the control of fine manual dexterity of the homolateral hand as assessed in a model of unilateral lesion of M1 in macaque monkeys. The Annual Meeting of the Swiss Society for Neuroscience (2009), Fribourg, Switzerland. 8. Alonso-Alonso M, Praeg E, Huang XL, Sidhu AS, Bashir S, Pascual-Leone A. Brain responses associated with the caloric content of food with and without awareness: relevance for uncontrolled eating. Society of Neuroscience (2009), 39th annual meeting, Oct. 17-21 in Chicago. 9. Schmidlin E, Hamadjida A, Baechler J, Bashir S, Belhaj-Saïf A, Rouiller E and Henri-Marcel H. Effect of anti Nogo-A antibody treatment on cortical lesion of the primary motor cortex (M1) of macaque monkeys assessed with Magnetic Resonance Imaging (MRI) correlated with manual dexterity recovery. Federation of European Neuroscience (2010) Amsterdam, Netherlands. 10. Pascual-Leone A, Oberman L, Freitas C, Stamoulis C, & Bashir S. Assessing cortical plasticity in health and disease across the human lifespan. Society of Neuroscience (2010), 40th annual meeting, San Diego, CA. 11. Luna Serrano M, Bashir S , Cáceres Taladriz C, Tormos Muñoz JM, Gómez Aguilera EJ, Pascual- Leone A. Aportaciones del guiado estereotáctico sin marco a la Estimulación Magnética Transcraneal con finalidades terapéuticas.CASEIB (2010) XXVIII Congreso Anual de la Sociedad Española de Ingeniería Biomédica, Madrid, Spain. 12. Marine VERNET, Shahid BASHIR, Edwin ROBERTSON, Alvaro PASCUAL-LEONE. Motor cortical and distributed network modulation during visuo-motor learning: a TMS-EEG study. Spain. Vision Science Society Meeting, May 2011, United State of America 13. Marine VERNET, Shahid BASHIR, Jennifer M. PEREZ, Umer NAJIB, Alvaro PASCUAL- LEONE. Motor plasticity induced by theta burst stimulation: correlated measures of MEPs and EEG. Organization for Human Brain Mapping, June 2011. Canada 14. Bashir S, Marine V, Woo-Kyoung Y, Ilan M, Hugo T and Pascual-Leone A. Noninvasive, Physiologic Characterization of Cortical Plasticity After Mild Traumatic Brain Injury in Humans. Organization for Human Brain Mapping, June 2011. Canada 15. Shahid Bashir, Marine Vernet, Umer Najib, Jennifer Perez, Miguel Alonso-Alonso, Mark Knobel, Woo-Kyoung Yoo, Dylan Edwards, Alvaro Pascual-Leone. Enhanced motor function and neurophysiological correlates with navigated low-frequency repetitive transcranial magnetic stimulation over the contralesional motor cortex in stroke. Brain Stimulation, 2015. Singpore 16. Shahid Bashir, Muhammad Iqbal , Abdullah Abu Jamea. Use of navigated transcranial magnetic brain stimulation in presurgical clinical applications. Saudi neurological society, 2016. Riyadh. 17. Shahid Bashir. A new medical device for non-invasive neuro-modulation and therapy with very low-intensity electrical currents. 5th Annual Saudi Epilepsy & 1st GCC Epilepsy Congress in Dammam from 5thnd to 7th November 2015, KSU, Saudi Arbia 18. Shahid Bashir. Clinical applications of Transcranial direct current stimulation: Must they start or should they still watch in developed and underdeveloped countries? PSNS 2016, Pakistan. 19. Abdullah Abu Jamea, Muhammed Alblowi, Fahad Alosaimi, Fahad Bader, Shahid Bashir. Altered default mode network activity as vulnerability indicators for schizophrenia: a preliminary resting state MRI study. Organization for Human Brain Mapping, June 2016, Geneva. 20. Abdullah Abu Jamea, Muhammed Alblowi, Fahad Alosaimi, Fahad Bader, Shahid Bashir. Altered
- 13. 13 default mode network activity as vulnerability indicators for schizophrenia: a preliminary resting state MRI study. Organization for Human Brain Mapping, June 2016, Geneva. 21. Abdullah Abu Jamea, Muhammed Alblowi, Fahad Alosaimi, Fahad Bader, Shahid Bashir. Volumetric and Shape Analysis of the subcortical in Patients With Schizophrenia. Pilot study. Organization for Human Brain Mapping, June 2016, Geneva. 22. Faisal AlGhamdi, Ahmed Alhussien, Meshal Alohali, Abdullah Alatawi, Tariq Almusned, Shahid Habib, Shahid Bashir. Effect of transcranial direct current stimulation on smoking craving among adult male population. FENS, July 2016, Copenhangen. Submitted manscripts under review: 1. Bashir S, Stephan M, Perret N, Paquier J, Fournier T, Vingerhoets F, Ruegg D, Diserens K. Climbing as therapy for the patients with cerebellar disorder part 1(pilot study). The Cerebellum, (under review). 2. Abdulrahman Al-Thaqib, Fahad Al-Sultan, Abdullah Al-Zahrani, Fahad Al-Qahtani, Khalid Al- Regaiey, Mohammed Iqbal , Shahid Bashir. 2016. Usage of brain training application among healthy subjects. Frointer Psychiatry (under revision). 3. Shahid Bashir, Woo-Kyoung Yoo, Hyoung Seop Kim, Alexander Rotenberg, Abdullah Abu Jamea. 2016. Differential Effects of the Eyes Open and Close Condition on the Motor Cortex Excitability in the Transcranial Magnetic Stimulation Protocol. Frointer Human neuroscience (under revision). 4. Nouf AlBacker , Shahid Bashir. 2016. Assessment of Parent Report and Actigraphy For Sleep in Children With Autism Spectrum Disorders. Pilot study. Neurology, Psychiatry and Brain Research 5. Shahid Bashir, Faisal Alghamdi, Ahmed Alhussien, Meshal Alohali, Abdullah Alatawi, Tariq Almusned. 2016. Effect of Smoking on Cognitive Functioning in Young Adults. Medical Principles and Practice 6. Ahmed Alhussien, Faisal Alghamdi, Meshal Alohali, Abdullah Alatawi, Tariq Almusned, Shahid Bashir. 2016. Prefrontal cortex modulation with transcranial direct current stimulation (tDCS) for nicotine craving reduction among Saudi population. Brain Stimulation (under revision). 7. Shahid Bashir. 2016. Effect of Transcranial Direct Current Stimulation on Autism: Pilot study. Brain Stimulation (under revision). 8. Shahid Bashir, Woo Kyoung Yoo, Shafiq Ahmad, Moath Alatefi, Abdullah Abu Juma. 2016. Inter- individual Variability In Motor Cortex Excitability Assessment Induced By Transcranial Direct Current Stimulation In Humans. Brain Stimulation (under revision). 9. Meshal Alohali, Ahmed Alhussien, Faisal Alghamdi, Abdullah Alatawi, Tariq Almusned, Shahid Bashir. 2016. Safety and Tolerability of Transcranial Direct Current Stimulation in Saudi Adult Population. Brain Stimulation (under revision). 10. Shahid, Bashir . 2016. The effect of transcranial direct current stimulation combined with functional task training on motor recovery in stroke patients. Pakistan journal of neurological science (under revision). 11. Shahid, Bashir, and Woo-Kyoung Yoo. 2016. . Transcrinal Direct current stimulation Technologies in Under-developed Countries (DUCs); Must they start or should they still watch?. Pakistan journal of neurological science. (under revision) 12. Shahid Bashir, Marine Vernet, Majed Alomar, Gulum Murtaza, Alexander Rotenberg and Woo- Kyoung Yoo. 2016. Human Brain Connectivity in Response to Paired Pulse TMS. Eur J Neurosci 13. Majed Alomar , Fawaz Al-Alhussien, Shahid Bashir. 2016. Cognitive impairment in Multiple Sclerosis study: Pilot study. Medical Principles and Practice 14. Fawaz Al-Hussain, Ghulam Murtaza, Mish'al Mohammed Alfallaj, Abdulaziz Nasser Alahmari, Abdullah Nasser Almazyad, Talal Khalid Alsaeed, Abdulmjeed Abdulaziz Abdurrahman, Shahid
- 14. 14 Bashir. 2016. The Relationship between Neutrophil-to-Lymphocyte Ratio and Stress in Multiple Sclerosis Patients. 15. Sultan Ayoub Meo, Shahid Bashir, Zaid Almubarak, Hisham Almutawa. 2016. Effect of Shisha Smoking on Cognitive Functions. 16. Muhammad Iqbal, Abu Jumna, Miguel Alonso-Alonso, Khalid Al Regaiey, Shahid Bashir. 2016. A Pilot study of the Neuroimaging, Neurocognitive and Body Composition Effects of Fasting in Ramadan. Eur J Neurosci 17. Bashir S, Alonso-Alonso M, Silvanto J and Pascual-Leone A. TMS and neuromoodulation assessment for racism. Cognitive neuroscience, (under review). 18. Catarina Freitas, Anna-Katharine Brem, Jennifer Perez, Mark Knobel, Jose M Tormos, Lindsay Oberman, Mark Eldaief, Shahid Bashir, Marine Vernet, Lukas Schilberg, Alvaro Pascual-Leone. (2012): Altered cortical plasticity in mild Alzheimer’s disease: Preliminary results. Annals of Neurology, (under review). 19. Shahid, Bashir, and Woo-Kyoung Yoo. Neuromodulation for addiction by transcranial direct current stimulation: opportunities and challenges. AANS 20. Abdullah Abu Jamea, Muhammed Alblowi, Fahad Alosaimi, Fahad Bader, Shahid Bashir. Altered default mode network activity as vulnerability indicators for schizophrenia: a preliminary resting state MRI study. 21. Abdullah Abu Jamea, Muhammed Alblowi, Fahad Alosaimi, Fahad Bader, Shahid Bashir. Volumetric and Shape Analysis of the subcortical in Patients With Schizophrenia. Pilot study. 22. Mohammed ALARABI, Abdullah AlTurki, Mohammed Mahasin, Abdulrahman AlSehly, Faisal AlDawood, Saleh AlKurini, Shahid Bashir. Cognitive Function and its Association with Level of Education and Work Status in Adults in Saudi Arabia: A Cross-Sectional Study. 23. Syed Shahid Habib, Shahid Bashir, Muhammad Iqbal, Ghadah Maher, Rawan Alyahya, Ghadeer Alzahrani, Sarah Alangari, Nourah Alrayesand Dahna Alkahtani. Cardiovascular Risk and Neurocognitive Assessment in Young Saudi Adults and their Relationship to Body Adiposity Studies completed manuscripts in preparation: 1. Praeg E, Bashir S, & Pascual-Leone A. Time specific activation increase in frontal and parietal areas after classical conditioning using TMS as unconditioned stimulus. Workshop and courses attented 2010 Instant Gratification, Multiple Selves, and Self- Control: How to Control Your Selves MBB 2010-2011 Distinguished Harvard Lecture. 2010 Building the Parallel Distributed Brain, How Do We Know? MBB 2010-2011 Distinguished Harvard Lecture. 2010 Automatic Brains, Interpretive Minds MBB 2010-2011 Distinguished Harvard Lecture. 2010 Feeling Free in a Mechanistic World: Where the Brain Meets the Law MBB 2010-2011 Distinguished Harvard Lecture. 2010 How a Cultural Innovation Changed Our Biology and Cognition MBB 2010-2011 Distinguished Harvard Lecture. 2009 The Translational Implications of Cognitive Neuroscience MBB 2009 Distinguished Harvard Lecture 2009 Battles in the Brain MBB 2009 Distinguished Harvard Lecture
- 15. 15 2009 My Body Has A Mind Of Its Own: So What Does It Need Me For? MBB 2009 Distinguished Harvard Lecture 2009 How Brains Become Minds: The Role Of Cultural Software MBB 2009 Distinguished Harvard Lecture 2008 Memory and Reality in Memory Disorders MBB 2008 Distinguished Harvard Lecture 2008 Dreaming and Waking: Whither Way Reality? MBB 2008 Distinguished Harvard Lecture 2008 The State of Cognitive Neuroscience: Accomplishments and Prospects MBB 2008 Distinguished Harvard Lecture 2008 The Linguistic Genius of Infants: Early Learning and Brain Plasticity MBB 2008 Distinguished Harvard Lecture 2008 The Infant Brain: Using Neuroscience Tools to Measure Neurolearning MBB 2008 Distinguished Harvard Lecture 2008 Genetic Frontiers of Neurologic Disease Symposium 2010 2008 Progress in Molecular Neurology: A Parkinson's Disease Perspective Symposium 2009 2008 Protein Folding and Neurodegeneration Symposium 2008 2008 Implementing and Managing Successful Clinical Studies Trustman Board Room 2011 “Learning from Experience: Successful Innovation at MIT” 65 Landsdowne Street, Cambridge 2011 The Cultural Competence in Research Symposium BIDMC 2011 Lifecycle of an imaging biomarker: From validation to dissemination Harvard 2010 Biomedical Imaging Resources: An Introduction MIT 2010 Comprehensive Clinical Management Workshop for the interdisciplinary management of patients with Spasticity or Movement Disorders Cambridge, Massachusetts 2012 Medial prefrontal contributions to social cognition NIBS 2012 Autism Genetics: A model for integrative study of common neurodevelopmental disorders BIDMC 2012 Breaching the Borders (IMMUNOLOGY SYMPOSIUM) Joseph B. Martin Conference Center Amphitheate 2012 The neural basis of reading: a contemporary synthesis BIDMC 2012 Network Science in Biology and Medicine Symposium MIT 2012 “Learning from Experience: Successful Innovation at MIT” 65 Landsdowne Street, Cambridge 2012 The Cultural Competence in Research Symposium MIT 2012 Instant Gratification, Multiple Selves, and Self- Control: How to Control Your Selves MBB 2010-2011 Distinguished Harvard Lecture. Narrative Report Research My graduate work at the University of Fribourg and Rehabilitation Center, CHUV Hospital, University of Lausanne, Switzerland engendered my interest in the field of neurological rehabilitation. My graduate work helped me develop clinical skills to work with neurological patients as well as technical skills related to programming and analysis of data. In my graduate work, I developed a keen interest in approaches to alleviate movement dysfunction following stroke and cerebellar disorders. The underlying neural mechanisms of movement recovery, however, were still not clear. I gained an opportunity to
- 16. 16 investigate this question in animal models of stroke under the supervision of Dr. Eric Rouiller. The main topic of my research was to study the anatomical neuronal regeneration in association with functional recovery after cortical lesions in adult primates. The mechanistic studies in primates intrigued me and encouraged me to explore neural mechanisms of recovery in adult humans using noninvasive techniques. To this effect, I am currently utilizing electrophysiological approaches, such as Electroencephalography (EEG) and Electromyography (EMG), along with neurophysiological stimulation methods including transcranial magnetic stimulation (TMS) and transcranial direct current stimulation (tDCS), as well as neuroimaging with functional magnetic resonance imaging, (fMRI). This ongoing research is being conducted under the mentorship and supervision of Dr. Alvaro Pascual-Leone at the Berenson-Allen Center for Noninvasive Brain Stimulation at Harvard Medical School. The preliminary results of our projects suggest that individuals with neurological disorders exhibit plasticity of surviving networks and that the degree of plasticity is highly correlated with behavioral measures and functional recovery. These findings provide an understanding of the potential mechanisms involving neuronal systems as well as other long-range cortical circuits. The graduate and post-doctoral experience in my research career has helped me progress towards my overall goal of becoming an independent and successful researcher in the area of clinical neuroscience and interventional neurophysiology involving patients with neurological disorders. Innovation in my research involves the combination of research tools and techniques (e.g. simultaneous electrophysiological recording and TMS) to provide data that any one technique cannot provide on its own. Furtheremore, I am to bridge levels of analyses by collaborating with molecular and genetic neuroscientists to further understand how more fundamental processes control the system’s level mechanisms. Teaching Over the course of my career in academic research I have taught formally and informally. While completing my PhD work at the University of Fribourg, Switzerland, I taught in the Neurophysiology practical course to second year medical students. More recently, since 2008, when I joined the Berenson- Allen Center for Noninvasive Brain Stimulation, I have been involved as faculty of the Intensive Course in Transcranial Magnetic Stimulation. This is a continuing medical education course through Harvard Medical School that is offered through the Center for Noninvasive Brain Stimulation. This course focuses on the theory and practical applications of TMS and is offered to a wide international audience of clinical
- 17. 17 and basic researchers. My involvement has been focused on the discussion of the safety aspects of the application of TMS, as well as the practical demonstration of the use of navigated TMS based on principles of MRI-guided frameless stereotaxy to deliver TMS over desired locations with great spatial precision. In King Saud University, I am involved in following teaching course at level of undergradue and postgradute for Sensory and Motor Systems, Behavioral and Cognitive Neuroscience, Introduction to Research in neuroscience , Disorders of the Nervous system. These course cover key neurological and psychiatric diseases. Part of each class session include an overview by a clinical expert, who will provide a clinical understanding of the disease, including signs and symptoms. A second part will be given by a scientist who does basic research in the field, who discuss experimental strategies and current hypotheses about pathophysiological mechanisms at the cellular and genetic level.