The Stack Exchange infrastructure supports 560 million page views and 34TB of data transferred per month across multiple technology stacks and datacenters. Performance is the top priority, and tools like Mini Profiler, OpServer, and Client Timings are used to monitor and improve performance. The infrastructure is designed with redundancy across networks, load balancers, web and database servers, caching, and search to ensure high availability and fast response times below 60ms for core pages.