This document summarizes New York City's experience implementing combination HIV prevention technologies. It discusses using the full range of available tools for HIV prevention, including structural interventions, clinical interventions, long-lasting protective interventions, and socioeconomic factors. It presents models for how various prevention strategies can reach different numbers of people and have varying levels of impact. It also highlights New York City's use of social media, rapid HIV testing technologies, treatment recommendations to offer treatment regardless of CD4 count, and nPEP programs as part of its combination prevention approach.