A 49-year-old man presented to the emergency department with 1 hour of severe anterior chest pain. An ECG showed normal sinus rhythm at 84 beats per minute with no signs of right or left atrial enlargement and a normal QRS axis and duration. The ECG revealed marked ST elevation in leads V1-V4, consistent with an antero-septal injury pattern diagnostic of an acute antero-septal myocardial infarction.