This document is a master's thesis submitted by Pieterjan Tilleman to the University of Ghent in 2013-2014. The thesis examines the use of proactive versus reactive risk management practices for managing supply chains. It includes a literature review on risk management, supply chain management, and supply chain risk management. The thesis presents a conceptual framework analyzing the influence of proactive and reactive risk strategies, moderated by supply chain management practices, design complexity, and other factors. Primary data was collected through a survey of Belgian companies and analyzed using statistical techniques including factor analysis and hypothesis testing. The results provide insight into how different approaches to risk management impact supply chain performance.