Tryggve support for-research
- 1. Support for Nordic research projects in managing sensitive data The Nordic Tryggve project https://wiki.neic.no/Tryggve
- 2. Tryggve – supporting biomedical research in Nordics 2 • Tryggve is a Nordic project that develops services for cross-border use of sensitive biomedical data for research – Partners and funders are NeIC and ELIXIR Nodes in Denmark, Finland, Norway and Sweden • The project supports genuine research projects through a continuous call for use cases • Use cases will receive e.g. support on legal and ethical questions, access to secure e-infrastructure, and expert assistance
- 3. Use cases 3
- 4. What is a Tryggve use case • Tryggve team wants to support researchers in taking the secure data services into use, and thereby to achieve results faster and safer – Tryggve use case is the concrete means of doing this! • Use case aims to solve real-life issues in data management and/or to provide state-of-the-art research environment for sensitive research data • Use cases can be proposed at any time via Tryggve’s web site: https://wiki.neic.no/wiki/Tryggve_Getting_Started 4
- 5. Suitability for Tryggve use case 5 Tryggve use case Research involves personal data Collaboration within Nordics
- 6. 6 Tryggve helps research projects to achieve their goals Collecting research data Storage and processing Publication and archival • Support in meeting legal and ethical requirements • Secure data transfer • Secure storage and computing environment • Share data with your colleagues • Software installations • Access to data archives • Secure data transfer
- 7. Collecting and moving research data • Support in the process of accessing and moving the data • Secure data transfer, based on secure FTP • Data can be moved between Nordic countries or from elsewhere, for example external repositories • Support in meeting legal and ethical requirements • Looking into specific questions, such as moving data across countries • Questions around merging research data from different sources • Professional evaluation of ethical and legal aspects 7
- 8. Storage and processing • Secure data analysis platforms • Project-based secure storage capacity • Efficient and secure processing environments • Tryggve offers environment, researcher brings the data • Variety of platforms offering flexibility to handle different use cases • Offering includes the following systems: TSD, Mosler, ePouta, Computerome • Share data with your colleagues • Control over the data stays with the user • Access to the data can be easily given to colleagues • Software installations • Support in moving computation where the data is • Guidance in installing the needed software 8
- 9. Publication and archival • Access to data archives • Support in moving data to international repositories when the analysis is done and data sets have been prepared for publication • Contacts to national archival services • Secure data transfer • Secure transfer to external repositories 9
- 10. In a nutshell • The proposers of accepted use cases will receive • Expert assistance from Tryggve • Access to secure data processing environments during the use case • Support in legal and ethical questions • Opportunity to influence future developments as an early adopter • All this will be provided free of charge for the use cases • The amount of computing or storage resources is subject to service owner’s decision • What we expect from researchers involved in a use case • Discussion with Tryggve team to specify the needs and to give input • Public abstract of the case 10
- 11. Selection process • Proposals can be submitted at any time • Main requirements for a use case proposal: – Involves use of sensitive data – Includes collaboration from more than one Nordic country • The proposal is analysed by the Tryggve project staff – This step is done interactively with the proposers – The project Reference Group may be consulted for recommendations • The project Steering Group makes final decisions • Key criteria for acceptance are the availability of expertise and resources at the project – Decisions can be done within a few weeks • More details at: https://wiki.neic.no/wiki/Tryggve_Getting_Started 11
- 12. Success story: Processing sensitive data for schizophrenia research • Research on the gene-environmental interaction and causes for schizophrenia, led by professor Patrick Sullivan, Karolinska Institutet. • Large samples are needed in order to understand the interactions between environment and genes. These are available in the Nordic countries because of long tradition for national registers. • Legal and ethical issues, ensuring the privacy of subjects, have to be taken into consideration when merging data. – Tryggve project has provided legal expertise and professional evaluation of the legal aspects of transferring the data sets between Nordic countries. • Secure place to conduct harmonized analyses of gene-environment interactions and risk of schizophrenia is crucial. – Professor Sullivan, with the assistance of Tryggve security experts, is now combining data sets from Denmark, Norway, Sweden and Estonia to create a joint data set with a total of 6000 cases and 8750 controls. • Read more: http://www.inthefieldstories.net/processing-sensitive-data-for- schizophrenia-research/ 12
- 13. Contact 13 Project Manager: Antti Pursula antti.pursula@csc.fi Website: wiki.neic.no/Tryggve Local contact points: Denmark: Ali Syed (DTU) alisyed@cbs.dtu.dk Finland: Antti Pursula (CSC) antti.pursula@csc.fi Norway: Francesca Iozzi (UiO) m.f.iozzi@usit.uio.no Sweden: Niclas Jareborg (NBIS) niclas.jareborg@bils.se