The document outlines the NAIS Challenge 20/20 program which pairs schools internationally to work on solving one of 20 global problems in the next 20 years. It provides examples of partnerships formed between schools to address issues like infectious diseases, water deficits, and global warming. Schools collaborate online and develop community service projects. The number of participating schools has grown from 75 in 2005 to over 400 in 2007 from around the world.