Herzberg's two-factor theory proposes that there are two sets of factors that influence job satisfaction and motivation: hygiene factors and motivators. Hygiene factors such as company policies, pay, and relationships can lead to dissatisfaction if absent but do not necessarily motivate. Motivators like achievement, recognition, responsibility, and advancement can positively motivate but will not de-motivate if absent. The document discusses applications of the theory in nursing research and concludes the theory provides practical solutions for organizations to improve job satisfaction.