England and Spain had disagreements over trade and religion in the late 1500s. In 1588, King Philip II of Spain sent the Spanish Armada to invade England but it was defeated, weakening Spain. England then began establishing colonies in North America but they struggled at first. The earliest colony at Roanoke Island failed after supplies from England did not arrive. The Jamestown colony, founded in 1607, also faced great hardships and loss of life in its early years until tobacco was successfully grown, providing an important cash crop. The colony survived and grew as the relationship with local Native Americans improved and more settlers, including women, arrived.