This document discusses significant figures and how they are used in chemistry measurements and calculations. It explains that nonzero digits and trailing zeros between nonzero digits are significant, while leading zeros and trailing zeros to the left of a decimal point are not. Numbers counted or from measurement systems have an unlimited number of significant figures. When adding or subtracting measurements, the answer should be rounded to the place value of the least precise measurement. For multiplication and division, the answer should be rounded to the same number of significant figures as the least precise factor or dividend.