DNA is made up of nucleotides that contain a sugar, phosphate group, and one of four nitrogenous bases: adenine, guanine, cytosine, or thymine. The nucleotides bond together to form two polynucleotide chains that wind around each other in a double helix formation. Hydrogen bonds connect the bases of one chain to the other. DNA contains the genetic code for making proteins and replicates itself for cell division.