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What Can You Do With
A Heart Rate Sensor?
© 2017 Valencell, Inc
Dr. Steven LeBoeuf
October 2017
©2017 Valencell. Incwww.valencell.com/patents
Highly accurate heart rate sensor data can be used to accurately
assess numerous biometrics
©2017 Valencell. Incwww.valencell.com/patents
Accurate biometric sensor data has been proven and validated for
fitness, health and medical assessments
Assessment Definition What is means for fitness What is means for health
VO2max Aerobic capacity – primary
measure of chronic change
to cardiovascular fitness
Higher VO2max is correlated
with better performance during
aerobic activities
Higher VO2max is correlated with lower
mortality & improved recovery from a cardiac
event [Anderson, Jetté, Kodama, Lee]
Resting Heart
Rate (HRrest)
HR during an awake period
of no exertion
Decreasing Resting HR is
correlated with increasing
fitness
Steadily increasing Resting HR is correlated
with the progression of cardiovascular
disease [Arnold, Fox, Nauman]
HR Recovery HR over 1-mintute after
intense exercise
Higher HR Recovery implies
better exercise endurance
Higher HR Recovery implies better
cardiovascular health[Ching, Cho, Lipinski, Nishime]
HR Response HR over 1-mintute at the
start of exercise
Higher HR Response can imply
low cardiac readiness for
exercise
Higher HR Response paired with
“chronotropic incompetence” can predict
carotid atherosclerosis [Falcone, Jaqoda, Jae,
Maddox, Myers]
Cardiac
Efficiency
Average cadence divided by
average heart rate (at
steady state): Cavg/HRavg
The higher cardiac efficiency,
the less heart beats are needed
for all physical activities
Steadily declining cardiac efficiency is
correlated with the onset of hypertension
[Laine, Sung]
HRV Heart rate variability --
statistical variability of RR-
intervals
HRV can diagnose
psychosocial stress &
overtraining in exercise
HRV can predict atrial fibrillation &
arrhythmia [Chon, Hohnloser, McManus, Park, Valkama]
©2017 Valencell. Incwww.valencell.com/patents
Atrial fibrillation identification has been demonstrated using
optical heart rate sensor systems
Valencell OHRM
ECG
Valencell OHRM
ECG
Normal Poincaré Plot Atrial Fibrillation Detected
©2017 Valencell. Incwww.valencell.com/patents
Accurate heart rate sensor data + scientifically validated use
cases =
PPG
Motion
Orientation
Sleep Stages
Blood Pressure
Oxygen Saturation
Core Body Temperature
Energy Expenditure
Hydration
Stress
Training Effect
Respiration Rate
©2017 Valencell. Incwww.valencell.com/patents
Core Body Temperature
• Indicator of overheating,
evidenced by changes in
heart rate
• Time oriented changes
during exercise
• Body’s ability to adapt to
heat increase during
exercise
(Link to paper)
©2017 Valencell. Incwww.valencell.com/patents
Another method to assess core body temp changes
employs activity context (user cadence)
©2017 Valencell. Incwww.valencell.com/patents
Energy Balance
• The importance of staying
in energy balance for
cardiovascular disease
preventuion is
well documented
• Sensor fusion is required
for sufficient monitoring
suitable for clinicial utility
Nobody’s there yet!
©2017 Valencell. Incwww.valencell.com/patents
Sleep Stages and Sleep Oriented Diseases
• Sleep oriented diseases
ex: sleep Apnea
• Detect disruptions in
breathing
• Differentiate between
sleep stages
• Sleep vs. wake stages
can be categorized via
HRV-based models
©2017 Valencell. Incwww.valencell.com/patents
Valencell’s internal research supports using
HR for sleep analsys
Good Sleep
Bad Sleep
©2017 Valencell. Incwww.valencell.com/patents
Physical/Mental Stress Assessments
• Worry-related stress can
be tracked using HR and
HRV analysis
• HRV analysis can by
used to assess one’s
ability to manage a
stressful event
• Stressors vs. stress can
be tracked with mobile
HRV implementations
• PPG amplitude also
correlates with stress
©2017 Valencell. Incwww.valencell.com/patents
Blood flow intensity (determined by PPG amplitude)
can be used to identify stressful events
Time (s)
Bloodflowintensity(a.u.)
Stress event 1
Stress event 2
Stress event 3
Q&A
Open Discussion
©2017 Valencell. Incwww.valencell.com/patents
Dr. Steven LeBoeuf

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What Can You Do With A Heart Rate Sensor?

  • 1. What Can You Do With A Heart Rate Sensor? © 2017 Valencell, Inc Dr. Steven LeBoeuf October 2017
  • 2. ©2017 Valencell. Incwww.valencell.com/patents Highly accurate heart rate sensor data can be used to accurately assess numerous biometrics
  • 3. ©2017 Valencell. Incwww.valencell.com/patents Accurate biometric sensor data has been proven and validated for fitness, health and medical assessments Assessment Definition What is means for fitness What is means for health VO2max Aerobic capacity – primary measure of chronic change to cardiovascular fitness Higher VO2max is correlated with better performance during aerobic activities Higher VO2max is correlated with lower mortality & improved recovery from a cardiac event [Anderson, Jetté, Kodama, Lee] Resting Heart Rate (HRrest) HR during an awake period of no exertion Decreasing Resting HR is correlated with increasing fitness Steadily increasing Resting HR is correlated with the progression of cardiovascular disease [Arnold, Fox, Nauman] HR Recovery HR over 1-mintute after intense exercise Higher HR Recovery implies better exercise endurance Higher HR Recovery implies better cardiovascular health[Ching, Cho, Lipinski, Nishime] HR Response HR over 1-mintute at the start of exercise Higher HR Response can imply low cardiac readiness for exercise Higher HR Response paired with “chronotropic incompetence” can predict carotid atherosclerosis [Falcone, Jaqoda, Jae, Maddox, Myers] Cardiac Efficiency Average cadence divided by average heart rate (at steady state): Cavg/HRavg The higher cardiac efficiency, the less heart beats are needed for all physical activities Steadily declining cardiac efficiency is correlated with the onset of hypertension [Laine, Sung] HRV Heart rate variability -- statistical variability of RR- intervals HRV can diagnose psychosocial stress & overtraining in exercise HRV can predict atrial fibrillation & arrhythmia [Chon, Hohnloser, McManus, Park, Valkama]
  • 4. ©2017 Valencell. Incwww.valencell.com/patents Atrial fibrillation identification has been demonstrated using optical heart rate sensor systems Valencell OHRM ECG Valencell OHRM ECG Normal Poincaré Plot Atrial Fibrillation Detected
  • 5. ©2017 Valencell. Incwww.valencell.com/patents Accurate heart rate sensor data + scientifically validated use cases = PPG Motion Orientation Sleep Stages Blood Pressure Oxygen Saturation Core Body Temperature Energy Expenditure Hydration Stress Training Effect Respiration Rate
  • 6. ©2017 Valencell. Incwww.valencell.com/patents Core Body Temperature • Indicator of overheating, evidenced by changes in heart rate • Time oriented changes during exercise • Body’s ability to adapt to heat increase during exercise (Link to paper)
  • 7. ©2017 Valencell. Incwww.valencell.com/patents Another method to assess core body temp changes employs activity context (user cadence)
  • 8. ©2017 Valencell. Incwww.valencell.com/patents Energy Balance • The importance of staying in energy balance for cardiovascular disease preventuion is well documented • Sensor fusion is required for sufficient monitoring suitable for clinicial utility Nobody’s there yet!
  • 9. ©2017 Valencell. Incwww.valencell.com/patents Sleep Stages and Sleep Oriented Diseases • Sleep oriented diseases ex: sleep Apnea • Detect disruptions in breathing • Differentiate between sleep stages • Sleep vs. wake stages can be categorized via HRV-based models
  • 10. ©2017 Valencell. Incwww.valencell.com/patents Valencell’s internal research supports using HR for sleep analsys Good Sleep Bad Sleep
  • 11. ©2017 Valencell. Incwww.valencell.com/patents Physical/Mental Stress Assessments • Worry-related stress can be tracked using HR and HRV analysis • HRV analysis can by used to assess one’s ability to manage a stressful event • Stressors vs. stress can be tracked with mobile HRV implementations • PPG amplitude also correlates with stress
  • 12. ©2017 Valencell. Incwww.valencell.com/patents Blood flow intensity (determined by PPG amplitude) can be used to identify stressful events Time (s) Bloodflowintensity(a.u.) Stress event 1 Stress event 2 Stress event 3