This document analyzes the decline in IPO activity in the U.S. since 2000. It presents a new hypothesis that the advantages of selling out to a larger organization, which can realize economies of scope and speed products to market, have increased over time relative to operating as an independent firm. The document finds evidence supporting this hypothesis but little support for alternative explanations like regulatory overreach. Key findings include a decline in small firm profitability predating regulatory changes, and an increase in M&A activity and delistings by recent IPOs being acquired by other public firms rather than going private.