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WHY CONTROVERSIES ARE OF
   CONTINUOUS RELEVANCE
PROF.A.V.SRINIVASAN, MD, DM, PhD, F.A.A.N,   F.I.A.N,


                       I



        Emeritus Professor, The
         Tamilnadu Dr.M.G.R.
          Medical University,
NOTHING NEW UNDER THE SUN



•   COCHRANE COLLOBORATION
•   MAVENS OF MCMASTER
•   JAMES LIND LIBRARY
•   www.jameslindlibrary .org
Evidence Based
   Medicine > Health Care > Practice
   Sackett et al (1996) defined Evidence Based Medicine as

    "the conscientious, explicit and
judicious use of current best evidence
 in making decisions about the care of
     the individual patient. It means
integrating individual clinical expertise
    with the best available external;
   clinical evidence from systematic
                research".
EBP at the micro level

The Processes of Evidence Based Practice
  – ASK (question formulation)
  – FIND (information seeking)
  – APPRAISE (critical awareness)
  – ACT (applicability)
  – EVALUATE (could I do it better?)
Finding & Appraising Evidence
 Evidence hierarchy
   – RCTs & Systematic Reviews
   – Case, cohort, pre-test/post test studies with controls
   – Expert opinion (extended anecdote)

 Cochrane Collaboration & its Library
  www.cochrane.org
 Campbell Collaboration
  www.campbellcollaboration.org
   – Social, Psychological, Educational, and Criminological
     Trials Register (C2-SPECTR)
   – Register of C2 Systematic Reviews of Interventions and
     Policy Evaluation (C2-RIPE)
HISTORY-
    EVIDENCE BASED MEDICINE


•   FIRST CONTROLLED TRIAL
•   BOOK OF DANIEL
•   (OLD TESTAMENT)
•   JAIN CHALMERS
•   2000BCE TO THE PRESENT TIME
HISTORY CONTD

      OLIVER WENDELL HOMES
               1861

• DANGERS OF CHANCE
• BIAS AND
• OF COURSE -LISTENING TO EXPERTS
INVETERATE LOGICAL ERRORS
1. COUNTING ONLY FAVOURABLE CASES
2. TABULATION OF FACTS –
3. ILL OBSERVED OR IMPROPERLY
   CLASSIFIED
4. FALSE INDUCTION FROM GENUINE FACTS
   (SCHOOL FO BROUSSAIS)
3. REASON OF THE GOLDEN TOOTH (SIR
   THOMAS BROWNE)
EVIDENCE BASED MEDICINE EXPERT MEDICINE-
             EXPERIENCE BASED

• Why is Evidence-Based Medicine
  Important in the Clinical Neurosciences

• Can Busy, Neurologists Practice
  Evidence-Based Medicine?
IDENTIFYING THE RESOURCES

• What EBCP Resources Are Available for
  the clinical Neurosciences?
• How Can EBCP Be introduced into
  Neurologic Training Programs?
• What Are Some Other Evidence –Based
  Neuroscience Initiatives
• Establishment of the Merit Center
Question + Resident +
                              MERIT Faculty +
                          Content Expert + Librarian




                      Publish (Intranet)                Formulate CAT
 Search
                      For Government                    Clinical Bottom
Articles(s)
                            Access                            Lines
 Appraise




   Presentation of
                                 1         2           Appraisal Summary
  Question / Search                                      and Discussion

        3 Sites
                                       3                    3 Sites



                                Individual Sites

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Why controversies are of continuous relevance

  • 1. WHY CONTROVERSIES ARE OF CONTINUOUS RELEVANCE PROF.A.V.SRINIVASAN, MD, DM, PhD, F.A.A.N, F.I.A.N, I Emeritus Professor, The Tamilnadu Dr.M.G.R. Medical University,
  • 2. NOTHING NEW UNDER THE SUN • COCHRANE COLLOBORATION • MAVENS OF MCMASTER • JAMES LIND LIBRARY • www.jameslindlibrary .org
  • 3. Evidence Based Medicine > Health Care > Practice Sackett et al (1996) defined Evidence Based Medicine as "the conscientious, explicit and judicious use of current best evidence in making decisions about the care of the individual patient. It means integrating individual clinical expertise with the best available external; clinical evidence from systematic research".
  • 4. EBP at the micro level The Processes of Evidence Based Practice – ASK (question formulation) – FIND (information seeking) – APPRAISE (critical awareness) – ACT (applicability) – EVALUATE (could I do it better?)
  • 5. Finding & Appraising Evidence Evidence hierarchy – RCTs & Systematic Reviews – Case, cohort, pre-test/post test studies with controls – Expert opinion (extended anecdote) Cochrane Collaboration & its Library www.cochrane.org Campbell Collaboration www.campbellcollaboration.org – Social, Psychological, Educational, and Criminological Trials Register (C2-SPECTR) – Register of C2 Systematic Reviews of Interventions and Policy Evaluation (C2-RIPE)
  • 6. HISTORY- EVIDENCE BASED MEDICINE • FIRST CONTROLLED TRIAL • BOOK OF DANIEL • (OLD TESTAMENT) • JAIN CHALMERS • 2000BCE TO THE PRESENT TIME
  • 7. HISTORY CONTD OLIVER WENDELL HOMES 1861 • DANGERS OF CHANCE • BIAS AND • OF COURSE -LISTENING TO EXPERTS
  • 8. INVETERATE LOGICAL ERRORS 1. COUNTING ONLY FAVOURABLE CASES 2. TABULATION OF FACTS – 3. ILL OBSERVED OR IMPROPERLY CLASSIFIED 4. FALSE INDUCTION FROM GENUINE FACTS (SCHOOL FO BROUSSAIS) 3. REASON OF THE GOLDEN TOOTH (SIR THOMAS BROWNE)
  • 9. EVIDENCE BASED MEDICINE EXPERT MEDICINE- EXPERIENCE BASED • Why is Evidence-Based Medicine Important in the Clinical Neurosciences • Can Busy, Neurologists Practice Evidence-Based Medicine?
  • 10. IDENTIFYING THE RESOURCES • What EBCP Resources Are Available for the clinical Neurosciences? • How Can EBCP Be introduced into Neurologic Training Programs? • What Are Some Other Evidence –Based Neuroscience Initiatives • Establishment of the Merit Center
  • 11. Question + Resident + MERIT Faculty + Content Expert + Librarian Publish (Intranet) Formulate CAT Search For Government Clinical Bottom Articles(s) Access Lines Appraise Presentation of 1 2 Appraisal Summary Question / Search and Discussion 3 Sites 3 3 Sites Individual Sites

Editor's Notes

  • #4: Sackett, D.L., Rosenberg, W.M.C., Muir Gray, J.A., Haynes, R.B., Richardson, W.S. (1996). Evidence-Based Medicine: what it is and what it isn't . British Medical Journal , 312:71-72) http:// cebm .jr2.ox.ac. uk / ebmisisnt .html
  • #5: Focusing the question Focusing the question is an important prerequisite of the search for evidence. A number of sites describe how this should be done: http://www.shef.ac.uk/~scharr/ir/focusing.html CASP Appraisal Tools http://www.phru.org.uk/~casp/appraisa.htm
  • #6: http://www.indigojazz.co.uk/cebm/levels_of_evidence.asp