This document discusses defense-in-depth strategies for securing databases in cloud environments. It describes how databases continue to be attractive targets for attackers due to the sensitive data they store. It then discusses how the hybrid cloud model raises new security concerns around data access and control. The document proposes a strategy of always-on encryption, centralized key management with Oracle Key Vault, configuration compliance monitoring, and restricting access to sensitive data with Oracle Database Vault to provide consistent security across on-premises and cloud databases.