The document discusses nine basic human instincts that relate to how people respond to change: loss aversion, emotion before reason, first impressions, gossip, confidence before realism, empathy and mind reading, contest and display, community, and hierarchy and status. It explains that people are more motivated to avoid loss than gain opportunity, and change will be resisted if it involves loss. It also notes that impressions and emotions shape initial responses to change before logical reasoning. The document provides tips for change leaders to be aware of these instincts to better understand and address resistance to change.