This document discusses developing applications with an offline-first approach using PouchDB and CouchDB/Cloudant. It begins with an introduction to NoSQL databases and outlines the benefits of offline-first development. It then provides details on using PouchDB to store and sync data locally on devices with CouchDB/Cloudant in the cloud. It covers creating, reading, updating and deleting documents, querying, and replicating data between PouchDB and CouchDB/Cloudant databases. It also discusses approaches for building offline web, hybrid mobile, and native iOS/Android apps with an offline-first design.