The document compiles frequently asked questions related to gram-negative bloodstream infections (GNBIs) and sepsis, highlighting data capture, epidemiology, community healthcare challenges, and NHS improvement initiatives. It emphasizes the importance of local understanding and cross-system collaboration in addressing GNBIs, alongside targets for reducing infections and improving reporting and leadership in healthcare settings. Additional resources for managing urinary tract infections and sepsis training are also provided, aiming to enhance prevention and control strategies across health systems.