The document discusses how simulation-based engineering science using high-performance computing clusters, grids, and clouds has allowed Goodyear to reduce expenditures on physical prototype building and testing by 62% and cut product design times by 67%, leading to unprecedented success with new products. It also presents middleware, services, applications, and portals that can be used to access and manage resources on clusters, grids, and clouds to support engineering tasks. Finally, an example engineering portal called EnginFrame is described that aims to address issues around complex IT infrastructures, team collaboration, and business opportunities in the engineering domain.