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                                                                                                                                                               Tuesday, April 27, 2010

  Home » News » BioInform
                                                                                                  In this issue of BioInform
  Shire Adds Hosted Version of IDBS' E-WorkBook to
                                                                                                      Biogen Idec Sees Promise in Network
  Support 'Virtual Model' for Drug Discovery                                                          Modeling to Identify New Autoimmune
                                                                                                      Disease Targets
  April 16, 2010
                                                                                                      At Network Bio Conference, Speakers
                                                                            Type size:                Highlight Role of Molecular Methods in
  By Vivien Marx                                                                                      Unraveling Cancer's Complexity
                                                                            Email
                                                                                                      VBI Study Indicates Prokaryotic Gene-
  IDBS said this week that biopharmaceutical firm Shire will use            Printer-friendly          Finding Algorithms Overlook Hundreds of
                                                                            version                   Gene Families
  its E-WorkBook Suite to support a "virtual model for
                                                                            RSS Feed                  EBI-Helsinki Team Integrates Array Data
  pharmaceutical research."
                                                                                                      from Thousands of Samples to Map Global
                                                                                                      'Expression Space'
  IDBS is implementing the electronic lab notebook suite as a hosted solution in
  collaboration with IT firm Quantix.

  Shire will use the hosted E-WorkBook solution in collaborations with contract research         Next Gen Sequencing
  organizations. Because the hosted approach will not require on-site data storage, it will
                                                                                                 Resource Center
  reduce the IT footprint for both Shire and its CRO partners, IDBS said. The deployment
  will give participants access to remote data and will also enable them to streamline               Targeting the Human Exome in Medical
  knowledge transfer between organizations.
                                                                                                     Re-sequencing
                                                                                                     Stacy Gabriel, Ph.D

  Shire is a new customer for IDBS, Chris Molloy, vice president of corporate                        Sequencing technologies—the next
  development for IDBS, told BioInform this week via e-mail.                                         generation
                                                                                                     Nature Reviews Genetics. 2010 Jan;11(1);31–46. Epub
                                                                                                     2009 Dec 8.
  E-WorkBook is a platform to capture, manage, and share research data. The hosted
                                                                                                     Download the Agilent NGS Application
  solution includes a security model that "addresses concerns around cloud computing"
                                                                                                     Guide
  so multiple CROs and other partners can share data, the company said.

  "Shire is pleased to take a leadership role in implementing this emerging business
  model of virtualized drug research, which uses new technologies to support novel
  working practices, improve collaboration, and speed the exploratory projects research,"          Young Investigator Profile
  Stephen Damment, senior vice president of biosciences at Shire, said in a statement.
                                                                                                   Blog

  Shire declined to provide further comment.                                                       Papers of Note

                                                                                                   People on the Move
  In this project, Shire and each of its CRO partners will be able to use E-WorkBook in a
  slightly different way for the capture, securing, and review of data, Molloy said. They will   Accelrys has appointed Todd Johnson to be executive
  "see only the data that they need to, while all the resultant IP remains fully protected       VP of sales and marketing services, and that Ilene Vogt
  and owned by Shire," he explained.                                                             has departed the company and left her post as senior
                                                                                                 VP of worldwide sales and services. Johnson joined
                                                                                                 Accelrys in 2009 as interim CEO, and after the firm
  IDBS said that it has previously implemented a multi-site hosted environment for E-
                                                                                                 tapped Max Carnecchia to take the helm, Johnson
  WorkBook with customers such as Australia's Cancer Therapeutics CRC, where it is               stepped into the role of senior VP.
  used by separate sites and groups to manage part of an overall research process.
                                                                                                 Harvard University Professor Raju Kucherlapati will
                                                                                                 serve as an Obama Administration adviser on genetic
  Other undisclosed pharma companies have also implemented E-Workbook this way,
                                                                                                 and genomic issues in his role as a member of the
  often in configurations with infrastructure-as-a-service suppliers behind the company
                                                                                                 Presidential Commission for the Study of Bioethical
  firewall, Molloy said.                                                                         Issues.


  The implementation is configured in order to "reassure companies that their electronic         OncoMethylome Sciences has named Jan Groen to
                                                                                                 take over as CEO. Groen formerly was president and
  collaboration systems will not leak IP to third parties and that their data-management
                                                                                                 COO of Agendia, and he was VP of R&D at Quest's
  infrastructure will be able to handle the size and complexity of the growing external          Focus Diagnostics subsidiary.
  research environment," Molloy said.

  Molloy said that since IDBS acquired InforSense last year (BI 7/6/2009), "we have                Upcoming Events

  taken the lead in demonstrating how to successfully integrate industry-leading
  [electronic lab notebook] and analytic technologies." For example, he said together the                                                                    Genetic Variation
  firms launched the "world's first biomarker ELN" in February and "already have made                                                                        Tech Guide Archives
  multiple sales."


  He acknowledged that the merger of Accelrys and Symyx, announced earlier this
  month (BI 4/9/2010), will present some competition. Accelrys offers the Pipeline Pilot
  workflow software, which competes with the InforSense technology, and Symyx brings
                                                                                                                                                           At AACR this week, Bert
  its own ELN to the combined entity.                                                                                                                      Vogelstein said that
                                                                                                                                                           cancer is a known entity.
  The merged firms "will still be a strong competitor in some chemistry market sectors but                                                                 Do you agree?
  IDBS remains highly differentiated," he said. "Our breadth of domain understanding,                                                                        Yes. We have the
  robust technologies, and ability to be a strategic player in higher-growth markets such                                                                  basics down.




http://www.genomeweb.com/informatics/shire-adds-hosted-version-idbs-e-workbook-... 27/04/2010
Shire Adds Hosted Version of IDBS' E-WorkBook to Support 'Virtual Model' for Dru... Page 2 of 2



  as regulated studies, biomarker R&D, and research biology clearly illustrates our                                                                 Sort of. We know
  differences."                                                                                                                                   enough to be dangerous.
                                                                                                                                                      Not really. We know a
                                                                                                                                                  lot, but there's so much
                                                                                                                                                  that we don't know.
  Related Stories
                                                                                                                                                     No. We're not even
                                                                                                                                                  close.
  As Microsoft Refines its Life Science Strategy, Some Bioinformatics Vendors Feel the
  Heat
                                                                                                                                                            Vote
  April 23, 2010 / BioInform
                                                                                                                                                        View Results
  IDBS, Tibco Spotfire to Integrate Chemistry Software Platforms
  April 23, 2010 / BioInform

  IDBS to Acquire InforSense to Expand Integration Offering, Life Science Presence
  July 6, 2009 / BioInform

  DNAnexus Launches Web-Based Sequence Analysis Service amid Continuing Debate
  over Cloud Computing
  April 23, 2010 / BioInform

  NextBio Launches Sequence-Centric Module to Enable Integration of Internal, Public
  Data
  April 23, 2010 / BioInform



    Science                           Business                        Funding
                                                                                                       Genome Technology Magazine
    At the American Association       BioMérieux and Knome will       Genome Canada plans to use
    for Cancer Research annual        collaborate on developing       the C$75 million in funding it   In this month's Brute Force column,
    meeting, National Institutes of   next-generation sequencing-     will receive under Canada's      Matthew Dublin says that while many
    Health Director Francis           based molecular diagnostics.    2010 budget to support the       people are concerned about the amount
    Collins and National Cancer       BioMérieux intends to           purchase of new technologies     of data generated by next-gen
    Institute Director John           develop cancer and infectious   and a wide array of research     sequencers, a more pressing concern
    Niederhuber highlighted           disease diagnostics using       efforts, which will emphasize    might be how to deal with analyzing that
    opportunities for researchers     Knome's sequence analysis       forestry, the environment,       data — especially when considering the
    to translate cancer research      technology and bioinformatic    human health, and                error rates associated with it.
    into clinical advances.           tools.                          agriculture.




Copyright © 2010 Genomeweb LLC. All rights reserved. About | FAQ | Subscriptions | Contact us




http://www.genomeweb.com/informatics/shire-adds-hosted-version-idbs-e-workbook-... 27/04/2010

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Quantix cloud case study

  • 1. Shire Adds Hosted Version of IDBS' E-WorkBook to Support 'Virtual Model' for Dru... Page 1 of 2 Log in or Register SEARCH Tuesday, April 27, 2010 Home » News » BioInform In this issue of BioInform Shire Adds Hosted Version of IDBS' E-WorkBook to Biogen Idec Sees Promise in Network Support 'Virtual Model' for Drug Discovery Modeling to Identify New Autoimmune Disease Targets April 16, 2010 At Network Bio Conference, Speakers Type size: Highlight Role of Molecular Methods in By Vivien Marx Unraveling Cancer's Complexity Email VBI Study Indicates Prokaryotic Gene- IDBS said this week that biopharmaceutical firm Shire will use Printer-friendly Finding Algorithms Overlook Hundreds of version Gene Families its E-WorkBook Suite to support a "virtual model for RSS Feed EBI-Helsinki Team Integrates Array Data pharmaceutical research." from Thousands of Samples to Map Global 'Expression Space' IDBS is implementing the electronic lab notebook suite as a hosted solution in collaboration with IT firm Quantix. Shire will use the hosted E-WorkBook solution in collaborations with contract research Next Gen Sequencing organizations. Because the hosted approach will not require on-site data storage, it will Resource Center reduce the IT footprint for both Shire and its CRO partners, IDBS said. The deployment will give participants access to remote data and will also enable them to streamline Targeting the Human Exome in Medical knowledge transfer between organizations. Re-sequencing Stacy Gabriel, Ph.D Shire is a new customer for IDBS, Chris Molloy, vice president of corporate Sequencing technologies—the next development for IDBS, told BioInform this week via e-mail. generation Nature Reviews Genetics. 2010 Jan;11(1);31–46. Epub 2009 Dec 8. E-WorkBook is a platform to capture, manage, and share research data. The hosted Download the Agilent NGS Application solution includes a security model that "addresses concerns around cloud computing" Guide so multiple CROs and other partners can share data, the company said. "Shire is pleased to take a leadership role in implementing this emerging business model of virtualized drug research, which uses new technologies to support novel working practices, improve collaboration, and speed the exploratory projects research," Young Investigator Profile Stephen Damment, senior vice president of biosciences at Shire, said in a statement. Blog Shire declined to provide further comment. Papers of Note People on the Move In this project, Shire and each of its CRO partners will be able to use E-WorkBook in a slightly different way for the capture, securing, and review of data, Molloy said. They will Accelrys has appointed Todd Johnson to be executive "see only the data that they need to, while all the resultant IP remains fully protected VP of sales and marketing services, and that Ilene Vogt and owned by Shire," he explained. has departed the company and left her post as senior VP of worldwide sales and services. Johnson joined Accelrys in 2009 as interim CEO, and after the firm IDBS said that it has previously implemented a multi-site hosted environment for E- tapped Max Carnecchia to take the helm, Johnson WorkBook with customers such as Australia's Cancer Therapeutics CRC, where it is stepped into the role of senior VP. used by separate sites and groups to manage part of an overall research process. Harvard University Professor Raju Kucherlapati will serve as an Obama Administration adviser on genetic Other undisclosed pharma companies have also implemented E-Workbook this way, and genomic issues in his role as a member of the often in configurations with infrastructure-as-a-service suppliers behind the company Presidential Commission for the Study of Bioethical firewall, Molloy said. Issues. The implementation is configured in order to "reassure companies that their electronic OncoMethylome Sciences has named Jan Groen to take over as CEO. Groen formerly was president and collaboration systems will not leak IP to third parties and that their data-management COO of Agendia, and he was VP of R&D at Quest's infrastructure will be able to handle the size and complexity of the growing external Focus Diagnostics subsidiary. research environment," Molloy said. Molloy said that since IDBS acquired InforSense last year (BI 7/6/2009), "we have Upcoming Events taken the lead in demonstrating how to successfully integrate industry-leading [electronic lab notebook] and analytic technologies." For example, he said together the Genetic Variation firms launched the "world's first biomarker ELN" in February and "already have made Tech Guide Archives multiple sales." He acknowledged that the merger of Accelrys and Symyx, announced earlier this month (BI 4/9/2010), will present some competition. Accelrys offers the Pipeline Pilot workflow software, which competes with the InforSense technology, and Symyx brings At AACR this week, Bert its own ELN to the combined entity. Vogelstein said that cancer is a known entity. The merged firms "will still be a strong competitor in some chemistry market sectors but Do you agree? IDBS remains highly differentiated," he said. "Our breadth of domain understanding, Yes. We have the robust technologies, and ability to be a strategic player in higher-growth markets such basics down. http://www.genomeweb.com/informatics/shire-adds-hosted-version-idbs-e-workbook-... 27/04/2010
  • 2. Shire Adds Hosted Version of IDBS' E-WorkBook to Support 'Virtual Model' for Dru... Page 2 of 2 as regulated studies, biomarker R&D, and research biology clearly illustrates our Sort of. We know differences." enough to be dangerous. Not really. We know a lot, but there's so much that we don't know. Related Stories No. We're not even close. As Microsoft Refines its Life Science Strategy, Some Bioinformatics Vendors Feel the Heat Vote April 23, 2010 / BioInform View Results IDBS, Tibco Spotfire to Integrate Chemistry Software Platforms April 23, 2010 / BioInform IDBS to Acquire InforSense to Expand Integration Offering, Life Science Presence July 6, 2009 / BioInform DNAnexus Launches Web-Based Sequence Analysis Service amid Continuing Debate over Cloud Computing April 23, 2010 / BioInform NextBio Launches Sequence-Centric Module to Enable Integration of Internal, Public Data April 23, 2010 / BioInform Science Business Funding Genome Technology Magazine At the American Association BioMérieux and Knome will Genome Canada plans to use for Cancer Research annual collaborate on developing the C$75 million in funding it In this month's Brute Force column, meeting, National Institutes of next-generation sequencing- will receive under Canada's Matthew Dublin says that while many Health Director Francis based molecular diagnostics. 2010 budget to support the people are concerned about the amount Collins and National Cancer BioMérieux intends to purchase of new technologies of data generated by next-gen Institute Director John develop cancer and infectious and a wide array of research sequencers, a more pressing concern Niederhuber highlighted disease diagnostics using efforts, which will emphasize might be how to deal with analyzing that opportunities for researchers Knome's sequence analysis forestry, the environment, data — especially when considering the to translate cancer research technology and bioinformatic human health, and error rates associated with it. into clinical advances. tools. agriculture. Copyright © 2010 Genomeweb LLC. All rights reserved. About | FAQ | Subscriptions | Contact us http://www.genomeweb.com/informatics/shire-adds-hosted-version-idbs-e-workbook-... 27/04/2010