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BRAIN RESEARCH
                              METHODS




Monday, 22 February 2010
BRAIN RESEARCH METHODS

               BRAINS ARE HARD TO STUDY BECAUSE THEY ARE
               SURROUNDED BY A SCULL




               IN THE PAST RESEARCH’S USED THE BRAINS OF DEAD PEOPLE
               AND ANIMALS. BUT THIS HAD MAJOR LIMITATIONS!!

               RESEARCH’S ALSO USED LIVING ANIMALS BUT THIS WAS
               HIGHLY UNETHICAL.

               IT HAS ONLY BEEN IN THE LATER HALF OF THE 20TH CENTURY
               THAT RESEARCH’S HAVE HAD THE TECHNOLOGY TO STUDY
               THE BRAIN EFFECTIVELY AND ETHICALLY.

Monday, 22 February 2010
CASE STUDIES

               WE CAN’T GO BUSTING HEADS IN ORDER TO SEE WHAT
               HAPPENS TO THE BRAIN. THIS IS UNETHICAL!

               THE ETHICAL WAY TO GO ABOUT STUDYING A PERSON WITH
               SOME DAMAGE TO THEIR BRAIN IS TO WAIT FOR THEM TO HAVE
               AN ACCIDENT AND THEN HOPE THEY ARE PREPARED TO ALLOW
               YOU TO STUDY THEM.

               STUDYING MEANS DOING ALL SORTS OF MEASUREMENTS
               LIKE, DIAGNOSTIC TESTS, INTERVIEWS, OBSERVATIONS, AND
               LOOKING AT MEDICAL RECORDS




Monday, 22 February 2010
ADVANTAGES

         •     LOTS OF INDEPTH DETAIL

         •     RICH AMOUNT OF INFO

               LIMITATIONS

         •     TAKE A LONG TIME TO GET INFORMATION

         •     INDIVIDUAL DIFFERENCES ARE NOT MEASURED

         •     PLASTICITY - THE BRAIN CAN ADAPT TO

         •     AS THEY ARE QUITE UNIQUE TO THE INDIVIDUAL, THE RESULTS CAN’T
               BE GENERALISED FAIRLY




Monday, 22 February 2010
ELECTRICAL STIMULATION OF THE
                   BRAIN (ESB)
                ELECTRICAL STIMULATION OF THE BRAIN INVOLVES USING AN
                ELECTRODE TO DELIVER AN ELECTRIC CURRENT TO THE BRAIN,
                THEN THAT PART OF THE BRAIN THAT RECEIVES THE CURRENT
                RESPONDS ACCORDINGLY.

                EXAMPLE: STIMULATING THE HYPOTHALAMUS IN ANIMALS
                EVOKES FEEDING, DRINKING, SEXUAL AROUSAL AND
                AGGRESSION DEPENDING ON THE AREA STIMULATED




Monday, 22 February 2010
ADVANTAGES

         • CAN PINPOINT LOCATION AND FUNCTION OF CERTAIN BRAIN
         STRUCTURES.
         • CAN HELP IDENTIFY HEMISPHERIC SPECIALISATION
              LIMITATIONS

         •    EXTREMELY INVASIVE - MUST APPLY DIRECTLY TO THE BRAIN

         •    CRUDE - NOT EASY TO TELL HOW FAR THE STIMULATION HAS SPREAD

         •    CAN’T ALWAYS BE GENERALISED TO ALL PEOPLE, AS ESB IS USUALLY
              DONE ON NOT PROPERLY FUNCTIONING BRAINS

         •    CAN ONLY BE USED ON THOSE UNDERGOING BRAIN SURGERY




Monday, 22 February 2010
ELECTROENCEPHALOGRAPH (EEG)

               THE EEG MEASURES ELECTRICAL ACTIVITY IN LOCALISED
               AREAS OF THE BRAIN. ELECTRODES ARE ATTACHED TO THE
               SURFACE OF THE SCALP AND THE ACTIVITY OF THE NEURONS
               ARE MEASURED.




Monday, 22 February 2010
ADVANTAGES

         • NON-INVASIVE

         • INEXPENSIVE AND SAFE CAN BE USED ON EVERYONE

         • CAN BE USED TO MEASURE OVER A LONG PERIOD OF TIME EG.
               SLEEP

               DISADVANTAGES

         • GENERAL MEASURE OF ACTIVITY

         • NOT AN IMAGING TECHNIQUE

         • SKULL CAN INTERFERE WITH ELECTRODE READING


Monday, 22 February 2010
COMPUTERISED TOMOGRAPHY
                      (CT OR CAT )
               CAT SCANS WERE THE FIRST NEURO-IMAGING TECHNIQUES

               CAT SCANS TAKE A NUMBER OF X-RAYS FROM DIFFERENT
               ANGLES TO PRODUCE A COMPTUTER IMAGE OF SLICES OF THE
               BRAIN




Monday, 22 February 2010
ADVANTAGES

         • NON-INVASIVE

         • PROVIDE VERY DETAILED IMAGE OF LIVING BRAIN

         • CAN FORM 3D IMAGE
               DISADVANTAGES

         • WILL ONLY SHOW STRUCTURE AND NOT FUNCTION

         • EXPENSIVE AND NEEDS HIGHLY QUALIFIED STAFF

         • MUST REMAIN STILL IN AN ENCLOSED SPACE

Monday, 22 February 2010
POSITRON EMISSION
                             TOMOGRAPHY
               A PET CONSTRUCTS A COMPUTER IMAGE OF BRAIN FUNCTION AND
               ACTIVITY. IT IS USED TO VIEW COGNITIVE AND BEHAVIORAL
               ACTIVITY WHEN PATIENTS ARE GIVEN A RANGE OF TASKS. RED
               INDICATES AREAS OF HIGH ACTIVITY, WHERE AS PURPLE
               INDICATES AREAS OF LOW ACTIVITY. A HARMLESS RADIOACTIVE
               SUBSTANCE IS INJECTED INTO THE PATIENT WHICH EMITS
               SIGNALS WHEN PRESENT IN THE BRAIN. A COMPUTER THEN READS
               THIS INFORMATION TO HELP COLOUR CODE THE IMAGE.




Monday, 22 February 2010
ADVANTAGES

         • YOU CAN SEE HOW THE BRAIN FUNCTIONS

         • YOU CAN SEE WHICH WHICH AREAS OF THE BRAIN ARE ACTIVE
               FOR CERTAIN TYPES OF TASKS

         • COLOR CODE MAKES THINGS EASY TO UNDERSTAND
               LIMITATIONS

         • NEED TO INJECT RADIOACTIVE MATERIAL INTO THE PERSON, SO
               SESSIONS MUST BE KEPT SHORT

         • ONLY ABLE TO VIEW THE BRAIN FOR A SHORT PERIOD OF TIME,
               AS IT TAKES 30 SECONDS TO SCAN AND YOU MUST REST FOR
               40 SECONDS BETWEEN SCANS


Monday, 22 February 2010
MAGNETIC RESONANCE IMAGING

               MAGNETIC AND RADIO WAVES BOUNCE OFF NEURONS IN THE
               BRAIN AND THESE VIBRATIONS ARE DETECTED BY A HUGE MAGNET
               IN THE MACHINE AND FED INTO A COMPUTER. THE COMPUTER
               THEN PROCESSEs THIS INFO AND CREATES A COLOUR CODED 3D
               IMAGE.  IT IS MORE DETAILED THAN A CT SCAN.

               IT IS USED TO DIAGNOSE STRUCTURAL ABNORMALITIES AND
               SMALL CHANGES OVER TIME. FOR EXAMPLE YOU CAN STUDY THE
               BRAIN OF A SCHIZOPHRENIA PATIENT  AND LOOK THE BRAIN
               CELLS CHANGE OVER TIME. IT IS MORE EXACT THAN A CT SCAN.




Monday, 22 February 2010
ADVANTAGES

         •     NON INVASIVE

         •     DETAILED AND CLEAR IMAGES OF THE BRAIN.

               LIMITATIONS

         •     THE INABILITY TO USE IT ON PEOPLE WITH METAL IN THEIR
               BODIES

         •     DOES NOT SHOW YOU THE FUNCTIONING ON THE BRAIN.

         •     CONFINED SPACE A PROBLEM




Monday, 22 February 2010
FUNCTIONAL MAGNETIC
                  RESONANCE IMAGING (FMRI)
               THE FMRI SHOWS HOW THE BRAIN IS FUNCTIONING BY
               MONITORING THE LEVELS OF OXYGEN IN THE BRAIN. THE HIGHER
               THE FUNCTIONING, THE HIGHER THE BLOOD FLOW.

               THE MAJOR DIFFERENCE BETWEEN AN FMRI AND A PET IS THAT IT
               CAN PICK UP CHANGES RAPIDLY, OVER SECONDS AS OPPOSED TO
               MINUTES. FMRI HAS ALSO BECOME 3D IN RECENT YEARS.




Monday, 22 February 2010
ADVANTAGES

         •     NO RADIATION

         •     SHOWS FUNCTIONING OF BRAIN

         •     COLOUR CODING MAKES IT EASY TO UNDERSTAND

         •     CAN TRACK BRAIN CHANGES MOMENT TO MOMENT

               LIMITATIONS

         •     ACTIVITY MAY BE A RESULT OF SOMETHING ELSE, OTHER THAN
               THE TASK GIVEN




Monday, 22 February 2010
CLARIFICATIONS

               INVASIVE: IN RELATION TO BRAIN RESEARCH, ANY TECHNIQUE
               THAT INVOLVES OPENING THE BRAIN UP.

               DIFFERENCE BETWEEN PET AND CT INJECTIONS.

         • CT - THE PARTICIPANT MUST BE INJECTED WITH A SUBSTANCE
               IN THE ARM OR HAND. THE SUBSTANCE IS BASED ON IODINE
               AND IS NOT RADIOACTIVE

         • PET - PRIOR TO THE PROCEDURE A RADIOACTIVE SUBSTANCE IS
               IS INJECTED INTO THE PATIENTS BLOOD VESSEL.




Monday, 22 February 2010
PRACTICE EXAM QUESTIONS




Monday, 22 February 2010
PRACTICE EXAM QUESTIONS

        Arthur has agreed to participate in a research study. In the study a small
        amount of radioactive substance will be injected into his blood vessels and
        transported to his brain. At the same time as the injection he will be asked to
        think of as many words as he can beginning with the letter L.




Monday, 22 February 2010
PRACTICE EXAM QUESTIONS

        Arthur has agreed to participate in a research study. In the study a small
        amount of radioactive substance will be injected into his blood vessels and
        transported to his brain. At the same time as the injection he will be asked to
        think of as many words as he can beginning with the letter L.
        What is this recording procedure known as?




Monday, 22 February 2010
PRACTICE EXAM QUESTIONS

        Arthur has agreed to participate in a research study. In the study a small
        amount of radioactive substance will be injected into his blood vessels and
        transported to his brain. At the same time as the injection he will be asked to
        think of as many words as he can beginning with the letter L.
        What is this recording procedure known as?
        A. EEG




Monday, 22 February 2010
PRACTICE EXAM QUESTIONS

        Arthur has agreed to participate in a research study. In the study a small
        amount of radioactive substance will be injected into his blood vessels and
        transported to his brain. At the same time as the injection he will be asked to
        think of as many words as he can beginning with the letter L.
        What is this recording procedure known as?
        A. EEG
        B. PET




Monday, 22 February 2010
PRACTICE EXAM QUESTIONS

        Arthur has agreed to participate in a research study. In the study a small
        amount of radioactive substance will be injected into his blood vessels and
        transported to his brain. At the same time as the injection he will be asked to
        think of as many words as he can beginning with the letter L.
        What is this recording procedure known as?
        A. EEG
        B. PET
        C. CT




Monday, 22 February 2010
PRACTICE EXAM QUESTIONS

        Arthur has agreed to participate in a research study. In the study a small
        amount of radioactive substance will be injected into his blood vessels and
        transported to his brain. At the same time as the injection he will be asked to
        think of as many words as he can beginning with the letter L.
        What is this recording procedure known as?
        A. EEG
        B. PET
        C. CT
        D. MRI




Monday, 22 February 2010
PRACTICE EXAM QUESTIONS

        Arthur has agreed to participate in a research study. In the study a small
        amount of radioactive substance will be injected into his blood vessels and
        transported to his brain. At the same time as the injection he will be asked to
        think of as many words as he can beginning with the letter L.
        What is this recording procedure known as?
        A. EEG
        B. PET
        C. CT
        D. MRI




Monday, 22 February 2010
PRACTICE EXAM QUESTIONS

        Arthur has agreed to participate in a research study. In the study a small
        amount of radioactive substance will be injected into his blood vessels and
        transported to his brain. At the same time as the injection he will be asked to
        think of as many words as he can beginning with the letter L.
        What is this recording procedure known as?
        A. EEG
        B. PET
        C. CT
        D. MRI




Monday, 22 February 2010
PRACTICE EXAM QUESTIONS

        Arthur has agreed to participate in a research study. In the study a small
        amount of radioactive substance will be injected into his blood vessels and
        transported to his brain. At the same time as the injection he will be asked to
        think of as many words as he can beginning with the letter L.
        What is this recording procedure known as?
        A. EEG
        B. PET
        C. CT
        D. MRI




Monday, 22 February 2010
PRACTICE EXAM QUESTIONS

        Arthur has agreed to participate in a research study. In the study a small
        amount of radioactive substance will be injected into his blood vessels and
        transported to his brain. At the same time as the injection he will be asked to
        think of as many words as he can beginning with the letter L.
        What is this recording procedure known as?
        A. EEG
        B. PET
        C. CT
        D. MRI




Monday, 22 February 2010
Arthur has agreed to participate in a research study. In the study a small amount of
         radioactive substance will be injected into his blood vessels and transported to his
         brain. At the same time as the injection he will be asked to think of as many words
         as he can beginning with the letter L.

         What is this recording procedure known as?
         A. EEG
         B. PET
         C. CT
         D. MRI

         Answer: B. PET




Monday, 22 February 2010
The brain scanning methods that provide the most comprehensive information
         on the functioning brain are _________ and __________.
         A. PET; fMRI
         B. CT; MRI
         C. MRI; fMRI
         D. CT; PET




Monday, 22 February 2010
The brain scanning methods that provide the most comprehensive information
         on the functioning brain are _________ and __________.
         A. PET; fMRI
         B. CT; MRI
         C. MRI; fMRI
         D. CT; PET

         Answer: A. PET; fMRI




Monday, 22 February 2010
Monday, 22 February 2010
Monday, 22 February 2010
Monday, 22 February 2010
Monday, 22 February 2010
One disadvantage of using an electroencephalograph (EEG) to investigate the
      brain is that




Monday, 22 February 2010
One disadvantage of using an electroencephalograph (EEG) to investigate the
      brain is that
      A. it cannot be used with a range of patients such as infants.




Monday, 22 February 2010
One disadvantage of using an electroencephalograph (EEG) to investigate the
      brain is that
      A. it cannot be used with a range of patients such as infants.
      B. it is invasive.




Monday, 22 February 2010
One disadvantage of using an electroencephalograph (EEG) to investigate the
      brain is that
      A. it cannot be used with a range of patients such as infants.
      B. it is invasive.
      C. it does not provide detailed information about brain function compared to
      positron emission tomography (PET).




Monday, 22 February 2010
One disadvantage of using an electroencephalograph (EEG) to investigate the
      brain is that
      A. it cannot be used with a range of patients such as infants.
      B. it is invasive.
      C. it does not provide detailed information about brain function compared to
      positron emission tomography (PET).
      D. it is expensive compared to functional magnetic resonance imaging
      (fMRI).




Monday, 22 February 2010
One disadvantage of using an electroencephalograph (EEG) to investigate the
      brain is that
      A. it cannot be used with a range of patients such as infants.
      B. it is invasive.
      C. it does not provide detailed information about brain function compared to
      positron emission tomography (PET).
      D. it is expensive compared to functional magnetic resonance imaging
      (fMRI).




Monday, 22 February 2010
One disadvantage of using an electroencephalograph (EEG) to investigate the
      brain is that
      A. it cannot be used with a range of patients such as infants.
      B. it is invasive.
      C. it does not provide detailed information about brain function compared to
      positron emission tomography (PET).
      D. it is expensive compared to functional magnetic resonance imaging
      (fMRI).




Monday, 22 February 2010
One disadvantage of using an electroencephalograph (EEG) to investigate the
      brain is that
      A. it cannot be used with a range of patients such as infants.
      B. it is invasive.
      C. it does not provide detailed information about brain function compared to
      positron emission tomography (PET).
      D. it is expensive compared to functional magnetic resonance imaging
      (fMRI).




Monday, 22 February 2010
One disadvantage of using an electroencephalograph (EEG) to investigate the
      brain is that
      A. it cannot be used with a range of patients such as infants.
      B. it is invasive.
      C. it does not provide detailed information about brain function compared to
      positron emission tomography (PET).
      D. it is expensive compared to functional magnetic resonance imaging
      (fMRI).




Monday, 22 February 2010
One disadvantage of using an electroencephalograph (EEG) to investigate the brain
       is that
       A. it cannot be used with a range of patients such as infants.
       B. it is invasive.
       C. it does not provide detailed information about brain function compared to
       positron emission tomography (PET).
       D. it is expensive compared to functional magnetic resonance imaging (fMRI).

       C. it does not provide detailed information about brain function compared to
       positron emission tomography (PET).




Monday, 22 February 2010
Which of the following is incorrect about computerised tomography (CT)
         scans?
         A. CT scans provide information about the function and extent of damage to
         the brain.
         B. The risks to the patient associated with CT scans are negligible.
         C. CT scans usually require an injection into the bloodstream.
         D. CT scans use X-rays taken at various angles to create an image of the brain.




Monday, 22 February 2010
Which of the following is incorrect about computerised tomography (CT)
         scans?
         A. CT scans provide information about the function and extent of damage to
         the brain.
         B. The risks to the patient associated with CT scans are negligible.
         C. CT scans usually require an injection into the bloodstream.
         D. CT scans use X-rays taken at various angles to create an image of the brain.

         A. CT scans provide information about the function and extent of damage
         to the brain.




Monday, 22 February 2010
A PET scan provides information

         A. in very high resolution pictures that show brain structure and function.
         B. in a colour-coded map that reveals areas of high activity in the brain.
         C. about abnormalities in the structure of the brain.
         D. about the number of cognitive tasks that were performed correctly.




Monday, 22 February 2010
A PET scan provides information

         A. in very high resolution pictures that show brain structure and function.
         B. in a colour-coded map that reveals areas of high activity in the brain.
         C. about abnormalities in the structure of the brain.
         D. about the number of cognitive tasks that were performed correctly.

         B. in a colour-coded map that reveals areas of high activity in the brain.




Monday, 22 February 2010
Monday, 22 February 2010
1. In terms of the potential risks to participants, describe one disadvantage of
         PET scanning in comparison with CT scanning. (1 mark)




Monday, 22 February 2010
1. In terms of the potential risks to participants, describe one disadvantage of
         PET scanning in comparison with CT scanning. (1 mark)




Monday, 22 February 2010
1. In terms of the potential risks to participants, describe one disadvantage of
         PET scanning in comparison with CT scanning. (1 mark)




Monday, 22 February 2010
1. In terms of the potential risks to participants, describe one disadvantage of
         PET scanning in comparison with CT scanning. (1 mark)




Monday, 22 February 2010
1. In terms of the potential risks to participants, describe one disadvantage of
         PET scanning in comparison with CT scanning. (1 mark)



         2. If a person has a metallic implant in their body, such as a heart pacemaker
         or a pin in a bone, they are advised not to undertake a certain brain scanning
         technique. What is the name of this technique? (1 mark)




Monday, 22 February 2010
1. In terms of the potential risks to participants, describe one disadvantage of
         PET scanning in comparison with CT scanning. (1 mark)



         2. If a person has a metallic implant in their body, such as a heart pacemaker
         or a pin in a bone, they are advised not to undertake a certain brain scanning
         technique. What is the name of this technique? (1 mark)




Monday, 22 February 2010
1. In terms of the potential risks to participants, describe one disadvantage of
         PET scanning in comparison with CT scanning. (1 mark)



         2. If a person has a metallic implant in their body, such as a heart pacemaker
         or a pin in a bone, they are advised not to undertake a certain brain scanning
         technique. What is the name of this technique? (1 mark)




Monday, 22 February 2010
1. In terms of the potential risks to participants, describe one disadvantage of PET
         scanning in comparison with CT scanning. (1 mark)

             The PET scan:
            • is more invasive
            • involves injecting a radioactive substance into the body.

         2. If a person has a metallic implant in their body, such as a heart pacemaker
         or a pin in a bone, they are advised not to undertake a certain brain scanning
         technique. What is the name of this technique? (1 mark)

         MRI or fMRI scanning




Monday, 22 February 2010
In positron emission tomography (PET) scans, a substance is tagged with a radioactive marker and then monitored. This substance is a form of
         A. iodine.
         B. kryptonite.
         C. uranium.
         D. glucose.

         D. glucose.



         Which procedure results in a high-quality three-dimensional picture of the brain?
         A. functional magnetic resonance imaging (fMRI) scan
         B. electrical stimulation of the brain (ESB) scan
         C. positron emission topography (PET) scan
         D. electroencephalograph (EEG) scan


         Which two procedures allow researchers to view changes in brain activity over time?
         A. positron emission topography (PET) scan and computerised tomography (CT) scan
         B. positron emission topography (PET) scan and functional magnetic resonance imaging (fMRI) scan
         C. magnetic resonance imaging (MRI) scan and functional magnetic resonance imaging (fMRI) scan
         D. computerised tomography (CT) scan and magnetic resonance imaging (MRI) scan




Monday, 22 February 2010
Monday, 22 February 2010
a. What information about the brain does positron emission tomography (PET) provide? (1 mark)




Monday, 22 February 2010
a. What information about the brain does positron emission tomography (PET) provide? (1 mark)




Monday, 22 February 2010
a. What information about the brain does positron emission tomography (PET) provide? (1 mark)

            the PET scan shows which areas of the brain are active while certain tasks are performed




Monday, 22 February 2010
a. What information about the brain does positron emission tomography (PET) provide? (1 mark)

            the PET scan shows which areas of the brain are active while certain tasks are performed




Monday, 22 February 2010
a. What information about the brain does positron emission tomography (PET) provide? (1 mark)

            the PET scan shows which areas of the brain are active while certain tasks are performed


            • the PET scan gives information about brain functioning.




Monday, 22 February 2010
a. What information about the brain does positron emission tomography (PET) provide? (1 mark)

            the PET scan shows which areas of the brain are active while certain tasks are performed


            • the PET scan gives information about brain functioning.




Monday, 22 February 2010
a. What information about the brain does positron emission tomography (PET) provide? (1 mark)

            the PET scan shows which areas of the brain are active while certain tasks are performed


            • the PET scan gives information about brain functioning.




Monday, 22 February 2010
a. What information about the brain does positron emission tomography (PET) provide? (1 mark)

            the PET scan shows which areas of the brain are active while certain tasks are performed


            • the PET scan gives information about brain functioning.



         b. When compared to computerised tomography (CT), outline one advantage of using positron emission tomography
         (PET). (1 mark)




Monday, 22 February 2010
a. What information about the brain does positron emission tomography (PET) provide? (1 mark)

            the PET scan shows which areas of the brain are active while certain tasks are performed


            • the PET scan gives information about brain functioning.



         b. When compared to computerised tomography (CT), outline one advantage of using positron emission tomography
         (PET). (1 mark)
         Advantages of PET include:




Monday, 22 February 2010
a. What information about the brain does positron emission tomography (PET) provide? (1 mark)

            the PET scan shows which areas of the brain are active while certain tasks are performed


            • the PET scan gives information about brain functioning.



         b. When compared to computerised tomography (CT), outline one advantage of using positron emission tomography
         (PET). (1 mark)
         Advantages of PET include:
            • CT is static while PET shows the brain in action




Monday, 22 February 2010
a. What information about the brain does positron emission tomography (PET) provide? (1 mark)

            the PET scan shows which areas of the brain are active while certain tasks are performed


            • the PET scan gives information about brain functioning.



         b. When compared to computerised tomography (CT), outline one advantage of using positron emission tomography
         (PET). (1 mark)
         Advantages of PET include:
            • CT is static while PET shows the brain in action

            • CT shows structural features and location of damage while PET shows functional areas




Monday, 22 February 2010
a. What information about the brain does positron emission tomography (PET) provide? (1 mark)

            the PET scan shows which areas of the brain are active while certain tasks are performed


            • the PET scan gives information about brain functioning.



         b. When compared to computerised tomography (CT), outline one advantage of using positron emission tomography
         (PET). (1 mark)
         Advantages of PET include:
            • CT is static while PET shows the brain in action

            • CT shows structural features and location of damage while PET shows functional areas

            • PET is more sensitive than CT in detecting areas of brain damage




Monday, 22 February 2010
a. What information about the brain does positron emission tomography (PET) provide? (1 mark)

            the PET scan shows which areas of the brain are active while certain tasks are performed


            • the PET scan gives information about brain functioning.



         b. When compared to computerised tomography (CT), outline one advantage of using positron emission tomography
         (PET). (1 mark)
         Advantages of PET include:
            • CT is static while PET shows the brain in action

            • CT shows structural features and location of damage while PET shows functional areas

            • PET is more sensitive than CT in detecting areas of brain damage

            • unlike CT scans, PET scans are colour-coded, which aids interpretation.




Monday, 22 February 2010
a. What information about the brain does positron emission tomography (PET) provide? (1 mark)

            the PET scan shows which areas of the brain are active while certain tasks are performed


            • the PET scan gives information about brain functioning.



         b. When compared to computerised tomography (CT), outline one advantage of using positron emission tomography
         (PET). (1 mark)
         Advantages of PET include:
            • CT is static while PET shows the brain in action

            • CT shows structural features and location of damage while PET shows functional areas

            • PET is more sensitive than CT in detecting areas of brain damage

            • unlike CT scans, PET scans are colour-coded, which aids interpretation.




Monday, 22 February 2010
a. What information about the brain does positron emission tomography (PET) provide? (1 mark)

            the PET scan shows which areas of the brain are active while certain tasks are performed


            • the PET scan gives information about brain functioning.



         b. When compared to computerised tomography (CT), outline one advantage of using positron emission tomography
         (PET). (1 mark)
         Advantages of PET include:
            • CT is static while PET shows the brain in action

            • CT shows structural features and location of damage while PET shows functional areas

            • PET is more sensitive than CT in detecting areas of brain damage

            • unlike CT scans, PET scans are colour-coded, which aids interpretation.


         This question demanded a speci7ic comparison; however, many students mistakenly compared PET scans with 
         other forms of brain‐imaging.




Monday, 22 February 2010
a. What information about the brain does positron emission tomography (PET) provide? (1 mark)

            the PET scan shows which areas of the brain are active while certain tasks are performed


            • the PET scan gives information about brain functioning.



         b. When compared to computerised tomography (CT), outline one advantage of using positron emission tomography
         (PET). (1 mark)
         Advantages of PET include:
            • CT is static while PET shows the brain in action

            • CT shows structural features and location of damage while PET shows functional areas

            • PET is more sensitive than CT in detecting areas of brain damage

            • unlike CT scans, PET scans are colour-coded, which aids interpretation.


         This question demanded a speci7ic comparison; however, many students mistakenly compared PET scans with 
         other forms of brain‐imaging.




Monday, 22 February 2010
Monday, 22 February 2010
c. What is the difference in the information provided by magnetic resonance imaging (MRI) and functional
               magnetic resonance imaging (fMRI)? (1 mark)




Monday, 22 February 2010
c. What is the difference in the information provided by magnetic resonance imaging (MRI) and functional
               magnetic resonance imaging (fMRI)? (1 mark)


               DIFFERENCES INCLUDE:




Monday, 22 February 2010
c. What is the difference in the information provided by magnetic resonance imaging (MRI) and functional
               magnetic resonance imaging (fMRI)? (1 mark)


               DIFFERENCES INCLUDE:


            • fMRI uses a magnetic field to create a three dimensional image of the brain where any two dimensional slice can be
                selected, and also displays brain activity on the screen




Monday, 22 February 2010
c. What is the difference in the information provided by magnetic resonance imaging (MRI) and functional
               magnetic resonance imaging (fMRI)? (1 mark)


               DIFFERENCES INCLUDE:


            • fMRI uses a magnetic field to create a three dimensional image of the brain where any two dimensional slice can be
                selected, and also displays brain activity on the screen

            • MRI shows only the structure of the brain.




Monday, 22 February 2010
c. What is the difference in the information provided by magnetic resonance imaging (MRI) and functional
               magnetic resonance imaging (fMRI)? (1 mark)


               DIFFERENCES INCLUDE:


            • fMRI uses a magnetic field to create a three dimensional image of the brain where any two dimensional slice can be
                selected, and also displays brain activity on the screen

            • MRI shows only the structure of the brain.




Monday, 22 February 2010

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Brain Research Methods Copy

  • 1. BRAIN RESEARCH METHODS Monday, 22 February 2010
  • 2. BRAIN RESEARCH METHODS BRAINS ARE HARD TO STUDY BECAUSE THEY ARE SURROUNDED BY A SCULL IN THE PAST RESEARCH’S USED THE BRAINS OF DEAD PEOPLE AND ANIMALS. BUT THIS HAD MAJOR LIMITATIONS!! RESEARCH’S ALSO USED LIVING ANIMALS BUT THIS WAS HIGHLY UNETHICAL. IT HAS ONLY BEEN IN THE LATER HALF OF THE 20TH CENTURY THAT RESEARCH’S HAVE HAD THE TECHNOLOGY TO STUDY THE BRAIN EFFECTIVELY AND ETHICALLY. Monday, 22 February 2010
  • 3. CASE STUDIES WE CAN’T GO BUSTING HEADS IN ORDER TO SEE WHAT HAPPENS TO THE BRAIN. THIS IS UNETHICAL! THE ETHICAL WAY TO GO ABOUT STUDYING A PERSON WITH SOME DAMAGE TO THEIR BRAIN IS TO WAIT FOR THEM TO HAVE AN ACCIDENT AND THEN HOPE THEY ARE PREPARED TO ALLOW YOU TO STUDY THEM. STUDYING MEANS DOING ALL SORTS OF MEASUREMENTS LIKE, DIAGNOSTIC TESTS, INTERVIEWS, OBSERVATIONS, AND LOOKING AT MEDICAL RECORDS Monday, 22 February 2010
  • 4. ADVANTAGES • LOTS OF INDEPTH DETAIL • RICH AMOUNT OF INFO LIMITATIONS • TAKE A LONG TIME TO GET INFORMATION • INDIVIDUAL DIFFERENCES ARE NOT MEASURED • PLASTICITY - THE BRAIN CAN ADAPT TO • AS THEY ARE QUITE UNIQUE TO THE INDIVIDUAL, THE RESULTS CAN’T BE GENERALISED FAIRLY Monday, 22 February 2010
  • 5. ELECTRICAL STIMULATION OF THE BRAIN (ESB) ELECTRICAL STIMULATION OF THE BRAIN INVOLVES USING AN ELECTRODE TO DELIVER AN ELECTRIC CURRENT TO THE BRAIN, THEN THAT PART OF THE BRAIN THAT RECEIVES THE CURRENT RESPONDS ACCORDINGLY. EXAMPLE: STIMULATING THE HYPOTHALAMUS IN ANIMALS EVOKES FEEDING, DRINKING, SEXUAL AROUSAL AND AGGRESSION DEPENDING ON THE AREA STIMULATED Monday, 22 February 2010
  • 6. ADVANTAGES • CAN PINPOINT LOCATION AND FUNCTION OF CERTAIN BRAIN STRUCTURES. • CAN HELP IDENTIFY HEMISPHERIC SPECIALISATION LIMITATIONS • EXTREMELY INVASIVE - MUST APPLY DIRECTLY TO THE BRAIN • CRUDE - NOT EASY TO TELL HOW FAR THE STIMULATION HAS SPREAD • CAN’T ALWAYS BE GENERALISED TO ALL PEOPLE, AS ESB IS USUALLY DONE ON NOT PROPERLY FUNCTIONING BRAINS • CAN ONLY BE USED ON THOSE UNDERGOING BRAIN SURGERY Monday, 22 February 2010
  • 7. ELECTROENCEPHALOGRAPH (EEG) THE EEG MEASURES ELECTRICAL ACTIVITY IN LOCALISED AREAS OF THE BRAIN. ELECTRODES ARE ATTACHED TO THE SURFACE OF THE SCALP AND THE ACTIVITY OF THE NEURONS ARE MEASURED. Monday, 22 February 2010
  • 8. ADVANTAGES • NON-INVASIVE • INEXPENSIVE AND SAFE CAN BE USED ON EVERYONE • CAN BE USED TO MEASURE OVER A LONG PERIOD OF TIME EG. SLEEP DISADVANTAGES • GENERAL MEASURE OF ACTIVITY • NOT AN IMAGING TECHNIQUE • SKULL CAN INTERFERE WITH ELECTRODE READING Monday, 22 February 2010
  • 9. COMPUTERISED TOMOGRAPHY (CT OR CAT ) CAT SCANS WERE THE FIRST NEURO-IMAGING TECHNIQUES CAT SCANS TAKE A NUMBER OF X-RAYS FROM DIFFERENT ANGLES TO PRODUCE A COMPTUTER IMAGE OF SLICES OF THE BRAIN Monday, 22 February 2010
  • 10. ADVANTAGES • NON-INVASIVE • PROVIDE VERY DETAILED IMAGE OF LIVING BRAIN • CAN FORM 3D IMAGE DISADVANTAGES • WILL ONLY SHOW STRUCTURE AND NOT FUNCTION • EXPENSIVE AND NEEDS HIGHLY QUALIFIED STAFF • MUST REMAIN STILL IN AN ENCLOSED SPACE Monday, 22 February 2010
  • 11. POSITRON EMISSION TOMOGRAPHY A PET CONSTRUCTS A COMPUTER IMAGE OF BRAIN FUNCTION AND ACTIVITY. IT IS USED TO VIEW COGNITIVE AND BEHAVIORAL ACTIVITY WHEN PATIENTS ARE GIVEN A RANGE OF TASKS. RED INDICATES AREAS OF HIGH ACTIVITY, WHERE AS PURPLE INDICATES AREAS OF LOW ACTIVITY. A HARMLESS RADIOACTIVE SUBSTANCE IS INJECTED INTO THE PATIENT WHICH EMITS SIGNALS WHEN PRESENT IN THE BRAIN. A COMPUTER THEN READS THIS INFORMATION TO HELP COLOUR CODE THE IMAGE. Monday, 22 February 2010
  • 12. ADVANTAGES • YOU CAN SEE HOW THE BRAIN FUNCTIONS • YOU CAN SEE WHICH WHICH AREAS OF THE BRAIN ARE ACTIVE FOR CERTAIN TYPES OF TASKS • COLOR CODE MAKES THINGS EASY TO UNDERSTAND LIMITATIONS • NEED TO INJECT RADIOACTIVE MATERIAL INTO THE PERSON, SO SESSIONS MUST BE KEPT SHORT • ONLY ABLE TO VIEW THE BRAIN FOR A SHORT PERIOD OF TIME, AS IT TAKES 30 SECONDS TO SCAN AND YOU MUST REST FOR 40 SECONDS BETWEEN SCANS Monday, 22 February 2010
  • 13. MAGNETIC RESONANCE IMAGING MAGNETIC AND RADIO WAVES BOUNCE OFF NEURONS IN THE BRAIN AND THESE VIBRATIONS ARE DETECTED BY A HUGE MAGNET IN THE MACHINE AND FED INTO A COMPUTER. THE COMPUTER THEN PROCESSEs THIS INFO AND CREATES A COLOUR CODED 3D IMAGE.  IT IS MORE DETAILED THAN A CT SCAN. IT IS USED TO DIAGNOSE STRUCTURAL ABNORMALITIES AND SMALL CHANGES OVER TIME. FOR EXAMPLE YOU CAN STUDY THE BRAIN OF A SCHIZOPHRENIA PATIENT  AND LOOK THE BRAIN CELLS CHANGE OVER TIME. IT IS MORE EXACT THAN A CT SCAN. Monday, 22 February 2010
  • 14. ADVANTAGES • NON INVASIVE • DETAILED AND CLEAR IMAGES OF THE BRAIN. LIMITATIONS • THE INABILITY TO USE IT ON PEOPLE WITH METAL IN THEIR BODIES • DOES NOT SHOW YOU THE FUNCTIONING ON THE BRAIN. • CONFINED SPACE A PROBLEM Monday, 22 February 2010
  • 15. FUNCTIONAL MAGNETIC RESONANCE IMAGING (FMRI) THE FMRI SHOWS HOW THE BRAIN IS FUNCTIONING BY MONITORING THE LEVELS OF OXYGEN IN THE BRAIN. THE HIGHER THE FUNCTIONING, THE HIGHER THE BLOOD FLOW. THE MAJOR DIFFERENCE BETWEEN AN FMRI AND A PET IS THAT IT CAN PICK UP CHANGES RAPIDLY, OVER SECONDS AS OPPOSED TO MINUTES. FMRI HAS ALSO BECOME 3D IN RECENT YEARS. Monday, 22 February 2010
  • 16. ADVANTAGES • NO RADIATION • SHOWS FUNCTIONING OF BRAIN • COLOUR CODING MAKES IT EASY TO UNDERSTAND • CAN TRACK BRAIN CHANGES MOMENT TO MOMENT LIMITATIONS • ACTIVITY MAY BE A RESULT OF SOMETHING ELSE, OTHER THAN THE TASK GIVEN Monday, 22 February 2010
  • 17. CLARIFICATIONS INVASIVE: IN RELATION TO BRAIN RESEARCH, ANY TECHNIQUE THAT INVOLVES OPENING THE BRAIN UP. DIFFERENCE BETWEEN PET AND CT INJECTIONS. • CT - THE PARTICIPANT MUST BE INJECTED WITH A SUBSTANCE IN THE ARM OR HAND. THE SUBSTANCE IS BASED ON IODINE AND IS NOT RADIOACTIVE • PET - PRIOR TO THE PROCEDURE A RADIOACTIVE SUBSTANCE IS IS INJECTED INTO THE PATIENTS BLOOD VESSEL. Monday, 22 February 2010
  • 19. PRACTICE EXAM QUESTIONS Arthur has agreed to participate in a research study. In the study a small amount of radioactive substance will be injected into his blood vessels and transported to his brain. At the same time as the injection he will be asked to think of as many words as he can beginning with the letter L. Monday, 22 February 2010
  • 20. PRACTICE EXAM QUESTIONS Arthur has agreed to participate in a research study. In the study a small amount of radioactive substance will be injected into his blood vessels and transported to his brain. At the same time as the injection he will be asked to think of as many words as he can beginning with the letter L. What is this recording procedure known as? Monday, 22 February 2010
  • 21. PRACTICE EXAM QUESTIONS Arthur has agreed to participate in a research study. In the study a small amount of radioactive substance will be injected into his blood vessels and transported to his brain. At the same time as the injection he will be asked to think of as many words as he can beginning with the letter L. What is this recording procedure known as? A. EEG Monday, 22 February 2010
  • 22. PRACTICE EXAM QUESTIONS Arthur has agreed to participate in a research study. In the study a small amount of radioactive substance will be injected into his blood vessels and transported to his brain. At the same time as the injection he will be asked to think of as many words as he can beginning with the letter L. What is this recording procedure known as? A. EEG B. PET Monday, 22 February 2010
  • 23. PRACTICE EXAM QUESTIONS Arthur has agreed to participate in a research study. In the study a small amount of radioactive substance will be injected into his blood vessels and transported to his brain. At the same time as the injection he will be asked to think of as many words as he can beginning with the letter L. What is this recording procedure known as? A. EEG B. PET C. CT Monday, 22 February 2010
  • 24. PRACTICE EXAM QUESTIONS Arthur has agreed to participate in a research study. In the study a small amount of radioactive substance will be injected into his blood vessels and transported to his brain. At the same time as the injection he will be asked to think of as many words as he can beginning with the letter L. What is this recording procedure known as? A. EEG B. PET C. CT D. MRI Monday, 22 February 2010
  • 25. PRACTICE EXAM QUESTIONS Arthur has agreed to participate in a research study. In the study a small amount of radioactive substance will be injected into his blood vessels and transported to his brain. At the same time as the injection he will be asked to think of as many words as he can beginning with the letter L. What is this recording procedure known as? A. EEG B. PET C. CT D. MRI Monday, 22 February 2010
  • 26. PRACTICE EXAM QUESTIONS Arthur has agreed to participate in a research study. In the study a small amount of radioactive substance will be injected into his blood vessels and transported to his brain. At the same time as the injection he will be asked to think of as many words as he can beginning with the letter L. What is this recording procedure known as? A. EEG B. PET C. CT D. MRI Monday, 22 February 2010
  • 27. PRACTICE EXAM QUESTIONS Arthur has agreed to participate in a research study. In the study a small amount of radioactive substance will be injected into his blood vessels and transported to his brain. At the same time as the injection he will be asked to think of as many words as he can beginning with the letter L. What is this recording procedure known as? A. EEG B. PET C. CT D. MRI Monday, 22 February 2010
  • 28. PRACTICE EXAM QUESTIONS Arthur has agreed to participate in a research study. In the study a small amount of radioactive substance will be injected into his blood vessels and transported to his brain. At the same time as the injection he will be asked to think of as many words as he can beginning with the letter L. What is this recording procedure known as? A. EEG B. PET C. CT D. MRI Monday, 22 February 2010
  • 29. Arthur has agreed to participate in a research study. In the study a small amount of radioactive substance will be injected into his blood vessels and transported to his brain. At the same time as the injection he will be asked to think of as many words as he can beginning with the letter L. What is this recording procedure known as? A. EEG B. PET C. CT D. MRI Answer: B. PET Monday, 22 February 2010
  • 30. The brain scanning methods that provide the most comprehensive information on the functioning brain are _________ and __________. A. PET; fMRI B. CT; MRI C. MRI; fMRI D. CT; PET Monday, 22 February 2010
  • 31. The brain scanning methods that provide the most comprehensive information on the functioning brain are _________ and __________. A. PET; fMRI B. CT; MRI C. MRI; fMRI D. CT; PET Answer: A. PET; fMRI Monday, 22 February 2010
  • 36. One disadvantage of using an electroencephalograph (EEG) to investigate the brain is that Monday, 22 February 2010
  • 37. One disadvantage of using an electroencephalograph (EEG) to investigate the brain is that A. it cannot be used with a range of patients such as infants. Monday, 22 February 2010
  • 38. One disadvantage of using an electroencephalograph (EEG) to investigate the brain is that A. it cannot be used with a range of patients such as infants. B. it is invasive. Monday, 22 February 2010
  • 39. One disadvantage of using an electroencephalograph (EEG) to investigate the brain is that A. it cannot be used with a range of patients such as infants. B. it is invasive. C. it does not provide detailed information about brain function compared to positron emission tomography (PET). Monday, 22 February 2010
  • 40. One disadvantage of using an electroencephalograph (EEG) to investigate the brain is that A. it cannot be used with a range of patients such as infants. B. it is invasive. C. it does not provide detailed information about brain function compared to positron emission tomography (PET). D. it is expensive compared to functional magnetic resonance imaging (fMRI). Monday, 22 February 2010
  • 41. One disadvantage of using an electroencephalograph (EEG) to investigate the brain is that A. it cannot be used with a range of patients such as infants. B. it is invasive. C. it does not provide detailed information about brain function compared to positron emission tomography (PET). D. it is expensive compared to functional magnetic resonance imaging (fMRI). Monday, 22 February 2010
  • 42. One disadvantage of using an electroencephalograph (EEG) to investigate the brain is that A. it cannot be used with a range of patients such as infants. B. it is invasive. C. it does not provide detailed information about brain function compared to positron emission tomography (PET). D. it is expensive compared to functional magnetic resonance imaging (fMRI). Monday, 22 February 2010
  • 43. One disadvantage of using an electroencephalograph (EEG) to investigate the brain is that A. it cannot be used with a range of patients such as infants. B. it is invasive. C. it does not provide detailed information about brain function compared to positron emission tomography (PET). D. it is expensive compared to functional magnetic resonance imaging (fMRI). Monday, 22 February 2010
  • 44. One disadvantage of using an electroencephalograph (EEG) to investigate the brain is that A. it cannot be used with a range of patients such as infants. B. it is invasive. C. it does not provide detailed information about brain function compared to positron emission tomography (PET). D. it is expensive compared to functional magnetic resonance imaging (fMRI). Monday, 22 February 2010
  • 45. One disadvantage of using an electroencephalograph (EEG) to investigate the brain is that A. it cannot be used with a range of patients such as infants. B. it is invasive. C. it does not provide detailed information about brain function compared to positron emission tomography (PET). D. it is expensive compared to functional magnetic resonance imaging (fMRI). C. it does not provide detailed information about brain function compared to positron emission tomography (PET). Monday, 22 February 2010
  • 46. Which of the following is incorrect about computerised tomography (CT) scans? A. CT scans provide information about the function and extent of damage to the brain. B. The risks to the patient associated with CT scans are negligible. C. CT scans usually require an injection into the bloodstream. D. CT scans use X-rays taken at various angles to create an image of the brain. Monday, 22 February 2010
  • 47. Which of the following is incorrect about computerised tomography (CT) scans? A. CT scans provide information about the function and extent of damage to the brain. B. The risks to the patient associated with CT scans are negligible. C. CT scans usually require an injection into the bloodstream. D. CT scans use X-rays taken at various angles to create an image of the brain. A. CT scans provide information about the function and extent of damage to the brain. Monday, 22 February 2010
  • 48. A PET scan provides information A. in very high resolution pictures that show brain structure and function. B. in a colour-coded map that reveals areas of high activity in the brain. C. about abnormalities in the structure of the brain. D. about the number of cognitive tasks that were performed correctly. Monday, 22 February 2010
  • 49. A PET scan provides information A. in very high resolution pictures that show brain structure and function. B. in a colour-coded map that reveals areas of high activity in the brain. C. about abnormalities in the structure of the brain. D. about the number of cognitive tasks that were performed correctly. B. in a colour-coded map that reveals areas of high activity in the brain. Monday, 22 February 2010
  • 51. 1. In terms of the potential risks to participants, describe one disadvantage of PET scanning in comparison with CT scanning. (1 mark) Monday, 22 February 2010
  • 52. 1. In terms of the potential risks to participants, describe one disadvantage of PET scanning in comparison with CT scanning. (1 mark) Monday, 22 February 2010
  • 53. 1. In terms of the potential risks to participants, describe one disadvantage of PET scanning in comparison with CT scanning. (1 mark) Monday, 22 February 2010
  • 54. 1. In terms of the potential risks to participants, describe one disadvantage of PET scanning in comparison with CT scanning. (1 mark) Monday, 22 February 2010
  • 55. 1. In terms of the potential risks to participants, describe one disadvantage of PET scanning in comparison with CT scanning. (1 mark) 2. If a person has a metallic implant in their body, such as a heart pacemaker or a pin in a bone, they are advised not to undertake a certain brain scanning technique. What is the name of this technique? (1 mark) Monday, 22 February 2010
  • 56. 1. In terms of the potential risks to participants, describe one disadvantage of PET scanning in comparison with CT scanning. (1 mark) 2. If a person has a metallic implant in their body, such as a heart pacemaker or a pin in a bone, they are advised not to undertake a certain brain scanning technique. What is the name of this technique? (1 mark) Monday, 22 February 2010
  • 57. 1. In terms of the potential risks to participants, describe one disadvantage of PET scanning in comparison with CT scanning. (1 mark) 2. If a person has a metallic implant in their body, such as a heart pacemaker or a pin in a bone, they are advised not to undertake a certain brain scanning technique. What is the name of this technique? (1 mark) Monday, 22 February 2010
  • 58. 1. In terms of the potential risks to participants, describe one disadvantage of PET scanning in comparison with CT scanning. (1 mark) The PET scan: • is more invasive • involves injecting a radioactive substance into the body. 2. If a person has a metallic implant in their body, such as a heart pacemaker or a pin in a bone, they are advised not to undertake a certain brain scanning technique. What is the name of this technique? (1 mark) MRI or fMRI scanning Monday, 22 February 2010
  • 59. In positron emission tomography (PET) scans, a substance is tagged with a radioactive marker and then monitored. This substance is a form of A. iodine. B. kryptonite. C. uranium. D. glucose. D. glucose. Which procedure results in a high-quality three-dimensional picture of the brain? A. functional magnetic resonance imaging (fMRI) scan B. electrical stimulation of the brain (ESB) scan C. positron emission topography (PET) scan D. electroencephalograph (EEG) scan Which two procedures allow researchers to view changes in brain activity over time? A. positron emission topography (PET) scan and computerised tomography (CT) scan B. positron emission topography (PET) scan and functional magnetic resonance imaging (fMRI) scan C. magnetic resonance imaging (MRI) scan and functional magnetic resonance imaging (fMRI) scan D. computerised tomography (CT) scan and magnetic resonance imaging (MRI) scan Monday, 22 February 2010
  • 61. a. What information about the brain does positron emission tomography (PET) provide? (1 mark) Monday, 22 February 2010
  • 62. a. What information about the brain does positron emission tomography (PET) provide? (1 mark) Monday, 22 February 2010
  • 63. a. What information about the brain does positron emission tomography (PET) provide? (1 mark) the PET scan shows which areas of the brain are active while certain tasks are performed Monday, 22 February 2010
  • 64. a. What information about the brain does positron emission tomography (PET) provide? (1 mark) the PET scan shows which areas of the brain are active while certain tasks are performed Monday, 22 February 2010
  • 65. a. What information about the brain does positron emission tomography (PET) provide? (1 mark) the PET scan shows which areas of the brain are active while certain tasks are performed • the PET scan gives information about brain functioning. Monday, 22 February 2010
  • 66. a. What information about the brain does positron emission tomography (PET) provide? (1 mark) the PET scan shows which areas of the brain are active while certain tasks are performed • the PET scan gives information about brain functioning. Monday, 22 February 2010
  • 67. a. What information about the brain does positron emission tomography (PET) provide? (1 mark) the PET scan shows which areas of the brain are active while certain tasks are performed • the PET scan gives information about brain functioning. Monday, 22 February 2010
  • 68. a. What information about the brain does positron emission tomography (PET) provide? (1 mark) the PET scan shows which areas of the brain are active while certain tasks are performed • the PET scan gives information about brain functioning. b. When compared to computerised tomography (CT), outline one advantage of using positron emission tomography (PET). (1 mark) Monday, 22 February 2010
  • 69. a. What information about the brain does positron emission tomography (PET) provide? (1 mark) the PET scan shows which areas of the brain are active while certain tasks are performed • the PET scan gives information about brain functioning. b. When compared to computerised tomography (CT), outline one advantage of using positron emission tomography (PET). (1 mark) Advantages of PET include: Monday, 22 February 2010
  • 70. a. What information about the brain does positron emission tomography (PET) provide? (1 mark) the PET scan shows which areas of the brain are active while certain tasks are performed • the PET scan gives information about brain functioning. b. When compared to computerised tomography (CT), outline one advantage of using positron emission tomography (PET). (1 mark) Advantages of PET include: • CT is static while PET shows the brain in action Monday, 22 February 2010
  • 71. a. What information about the brain does positron emission tomography (PET) provide? (1 mark) the PET scan shows which areas of the brain are active while certain tasks are performed • the PET scan gives information about brain functioning. b. When compared to computerised tomography (CT), outline one advantage of using positron emission tomography (PET). (1 mark) Advantages of PET include: • CT is static while PET shows the brain in action • CT shows structural features and location of damage while PET shows functional areas Monday, 22 February 2010
  • 72. a. What information about the brain does positron emission tomography (PET) provide? (1 mark) the PET scan shows which areas of the brain are active while certain tasks are performed • the PET scan gives information about brain functioning. b. When compared to computerised tomography (CT), outline one advantage of using positron emission tomography (PET). (1 mark) Advantages of PET include: • CT is static while PET shows the brain in action • CT shows structural features and location of damage while PET shows functional areas • PET is more sensitive than CT in detecting areas of brain damage Monday, 22 February 2010
  • 73. a. What information about the brain does positron emission tomography (PET) provide? (1 mark) the PET scan shows which areas of the brain are active while certain tasks are performed • the PET scan gives information about brain functioning. b. When compared to computerised tomography (CT), outline one advantage of using positron emission tomography (PET). (1 mark) Advantages of PET include: • CT is static while PET shows the brain in action • CT shows structural features and location of damage while PET shows functional areas • PET is more sensitive than CT in detecting areas of brain damage • unlike CT scans, PET scans are colour-coded, which aids interpretation. Monday, 22 February 2010
  • 74. a. What information about the brain does positron emission tomography (PET) provide? (1 mark) the PET scan shows which areas of the brain are active while certain tasks are performed • the PET scan gives information about brain functioning. b. When compared to computerised tomography (CT), outline one advantage of using positron emission tomography (PET). (1 mark) Advantages of PET include: • CT is static while PET shows the brain in action • CT shows structural features and location of damage while PET shows functional areas • PET is more sensitive than CT in detecting areas of brain damage • unlike CT scans, PET scans are colour-coded, which aids interpretation. Monday, 22 February 2010
  • 75. a. What information about the brain does positron emission tomography (PET) provide? (1 mark) the PET scan shows which areas of the brain are active while certain tasks are performed • the PET scan gives information about brain functioning. b. When compared to computerised tomography (CT), outline one advantage of using positron emission tomography (PET). (1 mark) Advantages of PET include: • CT is static while PET shows the brain in action • CT shows structural features and location of damage while PET shows functional areas • PET is more sensitive than CT in detecting areas of brain damage • unlike CT scans, PET scans are colour-coded, which aids interpretation. This question demanded a speci7ic comparison; however, many students mistakenly compared PET scans with  other forms of brain‐imaging. Monday, 22 February 2010
  • 76. a. What information about the brain does positron emission tomography (PET) provide? (1 mark) the PET scan shows which areas of the brain are active while certain tasks are performed • the PET scan gives information about brain functioning. b. When compared to computerised tomography (CT), outline one advantage of using positron emission tomography (PET). (1 mark) Advantages of PET include: • CT is static while PET shows the brain in action • CT shows structural features and location of damage while PET shows functional areas • PET is more sensitive than CT in detecting areas of brain damage • unlike CT scans, PET scans are colour-coded, which aids interpretation. This question demanded a speci7ic comparison; however, many students mistakenly compared PET scans with  other forms of brain‐imaging. Monday, 22 February 2010
  • 78. c. What is the difference in the information provided by magnetic resonance imaging (MRI) and functional magnetic resonance imaging (fMRI)? (1 mark) Monday, 22 February 2010
  • 79. c. What is the difference in the information provided by magnetic resonance imaging (MRI) and functional magnetic resonance imaging (fMRI)? (1 mark) DIFFERENCES INCLUDE: Monday, 22 February 2010
  • 80. c. What is the difference in the information provided by magnetic resonance imaging (MRI) and functional magnetic resonance imaging (fMRI)? (1 mark) DIFFERENCES INCLUDE: • fMRI uses a magnetic field to create a three dimensional image of the brain where any two dimensional slice can be selected, and also displays brain activity on the screen Monday, 22 February 2010
  • 81. c. What is the difference in the information provided by magnetic resonance imaging (MRI) and functional magnetic resonance imaging (fMRI)? (1 mark) DIFFERENCES INCLUDE: • fMRI uses a magnetic field to create a three dimensional image of the brain where any two dimensional slice can be selected, and also displays brain activity on the screen • MRI shows only the structure of the brain. Monday, 22 February 2010
  • 82. c. What is the difference in the information provided by magnetic resonance imaging (MRI) and functional magnetic resonance imaging (fMRI)? (1 mark) DIFFERENCES INCLUDE: • fMRI uses a magnetic field to create a three dimensional image of the brain where any two dimensional slice can be selected, and also displays brain activity on the screen • MRI shows only the structure of the brain. Monday, 22 February 2010