This document provides information on dental pit and fissure sealants, including their definition, history, properties, rationale for use, indications, contraindications, and application technique. Pit and fissure sealants are protective materials applied to the pits and grooves of teeth to prevent decay by isolating them from bacteria. They were first developed in the 1960s using bis-GMA resin and are now most commonly applied to posterior primary and permanent teeth judged to be at high risk of decay. Proper technique involves cleaning, etching, application of sealant, and curing either chemically or with visible light. Sealants are effective at preventing decay when applied correctly.