This document discusses how to calculate the margin of error when estimating population parameters from a sample. It defines the margin of error as the range of values above and below the sample statistic in a confidence interval. The margin of error is calculated using the critical value (from the t or z distribution) multiplied by the standard error of the statistic. The critical value depends on whether the sampling distribution is normal based on the central limit theorem and sample size. Common critical values for z are provided for various confidence levels when the sample size is large.