This document discusses the concept of total strong split domination in graphs, defining the total strong split domination number γtss(g) as the minimum size of a total strong split dominating set of a graph. The authors characterize total strong split dominating sets and establish inequalities and exact values for γtss(g) in various graph types. The work includes several theorems and propositions that provide insights into the properties and calculations of the total strong split domination number in different classes of graphs.