This document summarizes an e-book on clinical simulation in Spanish aimed at Spanish-speaking communities. The e-book contains over 12 chapters on the history, principles, standards, tools, and methods of clinical simulation. It includes translations of evaluation checklists, simulator manuals, and a glossary of simulation terms. The e-book is being revised and adapted to Spanish and will be made freely available online in March 2013. It aims to improve clinical simulation training and participation in international events for Spanish-speaking audiences. Initial use with various health programs suggests it can help increase adherence to best practices in simulation based on evidence for Spanish communities.