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Lateralization, Language,& Split Brain
LATERALIZATION
Lateralization refers to the idea that each 
hemisphere of the brain is specialized for 
different functions. 
(Nobel-prize-winners Roger 
Sperry and Robert Ornstein )
Lateralization, Language,& Split Brain
 helps us to understand our behavior, our 
personality, our creativity, and our ability 
to use the proper mode of thinking when 
performing particular tasks
 "brain dominance" -- the tendency to 
act and think in the mode of either the left 
or right hemisphere. 
 The decision is affected by our 
genetics, childhood experiences, 
and family environment
Tests of Cerebral Lateralization 
 Nearly all (about 95%) right-handed subjects are 
left-hemisphere dominant for speech; 
most left-handed or ambidextrous subjects (about 
70%) are also left-hemisphere dominant for speech; 
Early left-hemisphere damage can cause the 
right hemisphere to become dominant for 
speech and the left hand to be preferred
Sex Differences and Lateralization 
 Some evidence suggests that the male brain is 
more lateralized than female brain. 
e.g., McGlone’s (1977, 1980) studies of 
unilateral stroke 
victims and WAIS subscore tests 
 Some fMRI studies show that females 
tend to use both hemispheres in 
language-related tasks more so than males
So, if a brain functions based on hemispheres or 
separate areas, what would happen if a person lost 
half their brain? Would they still be able to 
function? Would they be able to survive? 
-Myers and Sperry, 1953-
LANGUANGE
Broca’s Area 
• In 1861, Paul Broca described a patient who 
could say only one word..."tan." For this reason, 
Broca called this patient "Tan." When Tan died, 
Broca examined his brain and found that there 
was damage to part of the left frontal cortex. This 
part of the brain has come to be known as 
"Broca's Area.“ 
• Broca's area (inferior frontal gyrus) is involved 
mostly in the production of speech, given its 
proximity to the motor cortex.
Wernicke's Area 
• In 1876, Karl Wernicke found that damage to a 
different part of the brain also caused 
language problems. This area of the brain 
“Wernicke's Area", was further back and lower 
in the brain compared to Broca's area. 
• Wernicke's area (posterior section of the 
superior temporal gyrus) is located relatively 
between the auditory cortex and the visual 
cortex.
Lateralization, Language,& Split Brain
APHASIA
• The acquired language disorders that are 
associated to brain activity are called 
aphasias. Depending on the location of the 
damage, the aphasias can present several 
differences.
Expressive Aphasia 
• Broca's aphasia 
• Usually characterized as a nonfluent aphasia 
• Prevents a person from producing speech 
• Words are not properly formed 
• Speech is slow and slurred. 
• Frequently omit small words.
• Have a hard time reproducing speech 
• Although most of their cognitive functions 
remain intact, and are still able to understand 
language. 
• They are aware of their language disorder and 
may get frustrated.
Receptive Aphasia 
• Wernicke's aphasia 
• Person can speak clearly, but the words that 
are put together make no sense. This way of 
speaking has been called "word salad" 
because it appears that the words are all 
mixed up like the vegetables in a salad.
• Loss of the ability to understand language 
• Hard time understanding what others try to 
communicate. 
• Often unaware of their mistakes.
Conduction Aphasia 
• Broca's area and Wernicke's area are 
connected by a bundle of nerve fibers called 
the arcuate fasciculus. 
• Damage to the arcuate fasciculus causes a 
disorder called conduction aphasia. 
• Can understand language, but their speech 
does not make sense and they cannot repeat 
words.
Lateralization, Language,& Split Brain
Electrical Stimulation 
• Early 1950s: Neurosurgeon Wilder Penfield & Herbert 
Jasper, described how electrical stimulation of certain 
areas of the brain blocked language. 
• By asking their patients questions during the surgical 
procedure. 
• Late 1980s, Dr. George Ojemann has used electrical 
stimulation experiments to show that there can be a 
large difference in the brain area that is important for 
language from person to person. 
• The results of these studies agree with the earlier 
findings of Broca and Wernicke.
Wada Test 
• Uses a fast acting anesthetic called sodium amytal 
(amobarbital) 
• Put one hemisphere of the brain asleep. 
• The sodium amytal is injected into the right or left 
carotid artery. The right artery supplies the right 
cerebral hemisphere and the left artery supplies the 
left cerebral hemisphere. 
• If the left hemisphere is put to sleep in people who 
have language ability in the left hemisphere, then 
when asked to speak, they cannot. However, if the 
right hemisphere is put to sleep, then these people will 
be able to speak and answer questions
Brain Imaging Techniques 
• Positron Emission Tomography (PET) 
• A scanner detects radioactive material that is 
injected or inhaled to create an image. 
• Many of the expected areas of the brain have 
increased blood flow during language tasks, 
but there are also areas on both hemispheres 
that are activated.
Dichotic listening 
• Patients will listen to conflicting stimuli in both 
ears and participants have to say what they 
hear. If they say what they heard from the left 
ear, then the right brain is the language brain 
because dominant ear is contralateral.
SPLIT BRAIN
SPLIT BRAIN
o Severed or absence of corpus callosum 
eliminate the main connection between the 
two hemispheres of the brain. 
Agenesis : born without corpus callosum 
Commissurotomy : performed on patients with 
life-threathening cases of epilepsy to decrease 
severity
i) Tachistoscope 
SPL IT BRAIN EXPERIMENT
ii) Chrimeric fiqure
Two independence streams of 
consciousness 
• When an object was presented to the left 
hemisphere, either by touching something 
with the right hand or viewing something in 
the right visual field, the subject could : 
– Pick out the correct object with the right hand 
– Could not pick out the correct object with the left 
hand 
– Could name the correct object
• When an object was presented to the right 
hemisphere, either by touching something 
with the left hand or viewing something in the 
left visual field, the subject could: 
– Could pick out the correct object with the left 
hand 
– Could not pick out the correct object with the 
right hand 
– Claimed nothing had been presented
"The great pleasure and feeling in my 
right brain is more than my left brain 
can find the words to tell you." 
Roger Sperry
Lateralization, Language,& Split Brain

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Lateralization, Language,& Split Brain

  • 3. Lateralization refers to the idea that each hemisphere of the brain is specialized for different functions. (Nobel-prize-winners Roger Sperry and Robert Ornstein )
  • 5.  helps us to understand our behavior, our personality, our creativity, and our ability to use the proper mode of thinking when performing particular tasks
  • 6.  "brain dominance" -- the tendency to act and think in the mode of either the left or right hemisphere.  The decision is affected by our genetics, childhood experiences, and family environment
  • 7. Tests of Cerebral Lateralization  Nearly all (about 95%) right-handed subjects are left-hemisphere dominant for speech; most left-handed or ambidextrous subjects (about 70%) are also left-hemisphere dominant for speech; Early left-hemisphere damage can cause the right hemisphere to become dominant for speech and the left hand to be preferred
  • 8. Sex Differences and Lateralization  Some evidence suggests that the male brain is more lateralized than female brain. e.g., McGlone’s (1977, 1980) studies of unilateral stroke victims and WAIS subscore tests  Some fMRI studies show that females tend to use both hemispheres in language-related tasks more so than males
  • 9. So, if a brain functions based on hemispheres or separate areas, what would happen if a person lost half their brain? Would they still be able to function? Would they be able to survive? -Myers and Sperry, 1953-
  • 11. Broca’s Area • In 1861, Paul Broca described a patient who could say only one word..."tan." For this reason, Broca called this patient "Tan." When Tan died, Broca examined his brain and found that there was damage to part of the left frontal cortex. This part of the brain has come to be known as "Broca's Area.“ • Broca's area (inferior frontal gyrus) is involved mostly in the production of speech, given its proximity to the motor cortex.
  • 12. Wernicke's Area • In 1876, Karl Wernicke found that damage to a different part of the brain also caused language problems. This area of the brain “Wernicke's Area", was further back and lower in the brain compared to Broca's area. • Wernicke's area (posterior section of the superior temporal gyrus) is located relatively between the auditory cortex and the visual cortex.
  • 15. • The acquired language disorders that are associated to brain activity are called aphasias. Depending on the location of the damage, the aphasias can present several differences.
  • 16. Expressive Aphasia • Broca's aphasia • Usually characterized as a nonfluent aphasia • Prevents a person from producing speech • Words are not properly formed • Speech is slow and slurred. • Frequently omit small words.
  • 17. • Have a hard time reproducing speech • Although most of their cognitive functions remain intact, and are still able to understand language. • They are aware of their language disorder and may get frustrated.
  • 18. Receptive Aphasia • Wernicke's aphasia • Person can speak clearly, but the words that are put together make no sense. This way of speaking has been called "word salad" because it appears that the words are all mixed up like the vegetables in a salad.
  • 19. • Loss of the ability to understand language • Hard time understanding what others try to communicate. • Often unaware of their mistakes.
  • 20. Conduction Aphasia • Broca's area and Wernicke's area are connected by a bundle of nerve fibers called the arcuate fasciculus. • Damage to the arcuate fasciculus causes a disorder called conduction aphasia. • Can understand language, but their speech does not make sense and they cannot repeat words.
  • 22. Electrical Stimulation • Early 1950s: Neurosurgeon Wilder Penfield & Herbert Jasper, described how electrical stimulation of certain areas of the brain blocked language. • By asking their patients questions during the surgical procedure. • Late 1980s, Dr. George Ojemann has used electrical stimulation experiments to show that there can be a large difference in the brain area that is important for language from person to person. • The results of these studies agree with the earlier findings of Broca and Wernicke.
  • 23. Wada Test • Uses a fast acting anesthetic called sodium amytal (amobarbital) • Put one hemisphere of the brain asleep. • The sodium amytal is injected into the right or left carotid artery. The right artery supplies the right cerebral hemisphere and the left artery supplies the left cerebral hemisphere. • If the left hemisphere is put to sleep in people who have language ability in the left hemisphere, then when asked to speak, they cannot. However, if the right hemisphere is put to sleep, then these people will be able to speak and answer questions
  • 24. Brain Imaging Techniques • Positron Emission Tomography (PET) • A scanner detects radioactive material that is injected or inhaled to create an image. • Many of the expected areas of the brain have increased blood flow during language tasks, but there are also areas on both hemispheres that are activated.
  • 25. Dichotic listening • Patients will listen to conflicting stimuli in both ears and participants have to say what they hear. If they say what they heard from the left ear, then the right brain is the language brain because dominant ear is contralateral.
  • 28. o Severed or absence of corpus callosum eliminate the main connection between the two hemispheres of the brain. Agenesis : born without corpus callosum Commissurotomy : performed on patients with life-threathening cases of epilepsy to decrease severity
  • 29. i) Tachistoscope SPL IT BRAIN EXPERIMENT
  • 31. Two independence streams of consciousness • When an object was presented to the left hemisphere, either by touching something with the right hand or viewing something in the right visual field, the subject could : – Pick out the correct object with the right hand – Could not pick out the correct object with the left hand – Could name the correct object
  • 32. • When an object was presented to the right hemisphere, either by touching something with the left hand or viewing something in the left visual field, the subject could: – Could pick out the correct object with the left hand – Could not pick out the correct object with the right hand – Claimed nothing had been presented
  • 33. "The great pleasure and feeling in my right brain is more than my left brain can find the words to tell you." Roger Sperry