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1. Contrast the functions of B cells and T
cells.
2. What are memory cells?
3. How do vaccines work?
4. How does HIV affect the immune
system?
1. Draw and label the parts of a neuron.
2. Describe saltatory conduction.
3. Explain how a nerve impulse is transmitted
across a neuron.
1. What happens at the synapse?
2. Choose 1 neurotransmitter. Describe its
action.
3. What is the role of the following structures
in the human brain?
a) Brainstem
b) Cerebellum
c) Cerebrum
d) Corpus callosum
Chapters 48 & 49
Campbell Biology – 9th ed.
¡ The anatomy of a neuron.
¡ The mechanisms of impulse transmission in a
neuron.
¡ The process that leads to release of
neurotransmitters, and what happens at the
synapse.
¡ How the vertebrate brain integrates
information, which leads to an appropriate
response.
¡ Different regions of the brain have different
functions.
¡ Central nervous system (CNS) = brain + spinal cord
¡ Peripheral nervous system (PNS) = nerves
throughout body
§ Sensory receptors: collect info
§ Sensory neurons: body à CNS
§ Motor neurons: CNS à body (muscles, glands)
§ Interneurons: connect sensory & motor neurons
¡ Nerves = bundles of neurons
§ Contains motor neurons +/or sensory neurons
13-Nervous-System from stem strand, learn now
13-Nervous-System from stem strand, learn now
13-Nervous-System from stem strand, learn now
Peripheral
nervous system
Somatic
nervous
system
Autonomic
nervous
system
Sympathetic
division
Parasympathetic
division
Enteric
division
13-Nervous-System from stem strand, learn now
13-Nervous-System from stem strand, learn now
¡ cell body: contains nucleus & organelles
¡ dendrites: receive incoming messages
¡ axons: transmit messages away to other cells
¡ myelin sheath: fatty insulation covering axon,
speeds up nerve impulses
¡ synapse: junction between 2 neurons
¡ neurotransmitter: chemical messengers sent across
synapse
¡ Glia: cells that support neurons
§ Eg. Schwann cells (forms myelin sheath)
13-Nervous-System from stem strand, learn now
13-Nervous-System from stem strand, learn now
Microelectrode
Reference
electrode
Voltage
recorder
–70 mV
The Na+/K+ pump (using ATP) maintains a
negative potential inside the neuron.
¡ Resting potential: membrane potential at rest;
polarized
§ ­Na+ outside, ­K+ inside cell
§ Voltage-gated Na+ channel = CLOSED
¡ Nerve impulse: stimulus causes a change in
membrane potential
§ Action potential: neuron membrane depolarizes
§ All-or-nothing response
Na+ channels
open
Na+ enters cell
K+ channels
open
K+ leaves cell
13-Nervous-System from stem strand, learn now
Conduction
of an action
potential
13-Nervous-System from stem strand, learn now
Saltatory conduction speed: 120 m/sec
13-Nervous-System from stem strand, learn now
13-Nervous-System from stem strand, learn now
¡ Chemicals released from vesicles by exocytosis into
synaptic cleft
¡ Diffuse across synapse
¡ Bind to receptors on neurons, muscle cells, or gland cells
¡ Broken down by enzymes or taken back up into
surrounding cells
¡ Types of neurotransmitters:
§ Excitatory: speed up impulses by causing
depolarization of postsynaptic membrane
§ Inhibitory: slow impulses by causing hyperpolarization
of postsynaptic membrane
13-Nervous-System from stem strand, learn now
¡ Acetylcholine (ACh): stimulates muscles, memory
formation, learning
¡ Epinephrine: (adrenaline) fight-or-flight
¡ Norepinephrine: fight-or-flight
¡ Dopamine: reward, pleasure (“high”)
§ Loss of dopamine à Parkinson’s Disease
¡ Serotonin: well-being, happiness
§ Low levels à Depression
¡ GABA: inhibitory NT
§ Affected by alcohol
13-Nervous-System from stem strand, learn now
Poster Presentation:
¡ Drug:
¡ Neurotransmitter(s) Involved
¡ Action of Drug:
¡ Summary Illustration
¡ Simple, automatic response to a stimulus
¡ Conscious thought not required
¡ Reflex arc:
1. Stimulus detected by receptor
2. Sensory neuron
3. Interneuron (spinal cord or brain stem)
4. Motor neuron
5. Response by effector organ (muscles, glands)
13-Nervous-System from stem strand, learn now
13-Nervous-System from stem strand, learn now
Major Regions: forebrain, midbrain, hindbrain
• Forebrain à cerebrum
• Midbrain à brainstem
• Hindbrain à cerebellum
Structure Function
Cerebrum • Information processing (learning, emotion,
memory, perception, voluntary movement)
• Right & Left cerebral hemispheres
• Corpus callosum: connect hemispheres
Brainstem *Oldest evolutionary part*
•Basic, autonomic survival behaviors
•Medulla oblongata –breathing, heart & blood
vessel activity, digestion, swallowing, vomiting
•Transfer info between PNS & CNS
Cerebellum • Coordinate movement & balance
• Motor skill learning
Structure Function
Cerebrum • Information processing (learning, emotion,
memory, perception, voluntary movement)
• Right & Left cerebral hemispheres
• Corpus callosum: connect hemispheres
Brainstem *Oldest evolutionary part*
•Basic, autonomic survival behaviors
•Medulla oblongata –breathing, heart & blood
vessel activity, digestion, swallowing, vomiting
•Transfer info between PNS & CNS
Cerebellum • Coordinate movement & balance
• Motor skill learning
Human Brain
Structure Function
Cerebrum • Information processing (learning, emotion,
memory, perception, voluntary movement)
• Right & Left cerebral hemispheres
• Corpus callosum: connect hemispheres
Brainstem *Oldest evolutionary part*
•Basic, autonomic survival behaviors
•Medulla oblongata –breathing, heart & blood
vessel activity, digestion, swallowing, vomiting
•Transfer info between PNS & CNS
Cerebellum • Coordinate movement & balance
• Motor skill learning
Human Brain
Structure Function
Cerebrum • Information processing (learning, emotion,
memory, perception, voluntary movement)
• Right & Left cerebral hemispheres
• Corpus callosum: connect hemispheres
Brainstem *Oldest evolutionary part*
•Basic, autonomic survival behaviors
•Medulla oblongata –breathing, heart & blood
vessel activity, digestion, swallowing, vomiting
•Transfer info between PNS & CNS
Cerebellum • Coordinate movement & balance
• Motor skill learning
Human Brain
13-Nervous-System from stem strand, learn now
13-Nervous-System from stem strand, learn now

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13-Nervous-System from stem strand, learn now

  • 1. 1. Contrast the functions of B cells and T cells. 2. What are memory cells? 3. How do vaccines work? 4. How does HIV affect the immune system?
  • 2. 1. Draw and label the parts of a neuron. 2. Describe saltatory conduction. 3. Explain how a nerve impulse is transmitted across a neuron.
  • 3. 1. What happens at the synapse? 2. Choose 1 neurotransmitter. Describe its action. 3. What is the role of the following structures in the human brain? a) Brainstem b) Cerebellum c) Cerebrum d) Corpus callosum
  • 4. Chapters 48 & 49 Campbell Biology – 9th ed.
  • 5. ¡ The anatomy of a neuron. ¡ The mechanisms of impulse transmission in a neuron. ¡ The process that leads to release of neurotransmitters, and what happens at the synapse. ¡ How the vertebrate brain integrates information, which leads to an appropriate response. ¡ Different regions of the brain have different functions.
  • 6. ¡ Central nervous system (CNS) = brain + spinal cord ¡ Peripheral nervous system (PNS) = nerves throughout body § Sensory receptors: collect info § Sensory neurons: body à CNS § Motor neurons: CNS à body (muscles, glands) § Interneurons: connect sensory & motor neurons ¡ Nerves = bundles of neurons § Contains motor neurons +/or sensory neurons
  • 13. ¡ cell body: contains nucleus & organelles ¡ dendrites: receive incoming messages ¡ axons: transmit messages away to other cells ¡ myelin sheath: fatty insulation covering axon, speeds up nerve impulses ¡ synapse: junction between 2 neurons ¡ neurotransmitter: chemical messengers sent across synapse ¡ Glia: cells that support neurons § Eg. Schwann cells (forms myelin sheath)
  • 17. The Na+/K+ pump (using ATP) maintains a negative potential inside the neuron.
  • 18. ¡ Resting potential: membrane potential at rest; polarized § ­Na+ outside, ­K+ inside cell § Voltage-gated Na+ channel = CLOSED ¡ Nerve impulse: stimulus causes a change in membrane potential § Action potential: neuron membrane depolarizes § All-or-nothing response Na+ channels open Na+ enters cell K+ channels open K+ leaves cell
  • 25. ¡ Chemicals released from vesicles by exocytosis into synaptic cleft ¡ Diffuse across synapse ¡ Bind to receptors on neurons, muscle cells, or gland cells ¡ Broken down by enzymes or taken back up into surrounding cells ¡ Types of neurotransmitters: § Excitatory: speed up impulses by causing depolarization of postsynaptic membrane § Inhibitory: slow impulses by causing hyperpolarization of postsynaptic membrane
  • 27. ¡ Acetylcholine (ACh): stimulates muscles, memory formation, learning ¡ Epinephrine: (adrenaline) fight-or-flight ¡ Norepinephrine: fight-or-flight ¡ Dopamine: reward, pleasure (“high”) § Loss of dopamine à Parkinson’s Disease ¡ Serotonin: well-being, happiness § Low levels à Depression ¡ GABA: inhibitory NT § Affected by alcohol
  • 29. Poster Presentation: ¡ Drug: ¡ Neurotransmitter(s) Involved ¡ Action of Drug: ¡ Summary Illustration
  • 30. ¡ Simple, automatic response to a stimulus ¡ Conscious thought not required ¡ Reflex arc: 1. Stimulus detected by receptor 2. Sensory neuron 3. Interneuron (spinal cord or brain stem) 4. Motor neuron 5. Response by effector organ (muscles, glands)
  • 33. Major Regions: forebrain, midbrain, hindbrain
  • 34. • Forebrain à cerebrum • Midbrain à brainstem • Hindbrain à cerebellum
  • 35. Structure Function Cerebrum • Information processing (learning, emotion, memory, perception, voluntary movement) • Right & Left cerebral hemispheres • Corpus callosum: connect hemispheres Brainstem *Oldest evolutionary part* •Basic, autonomic survival behaviors •Medulla oblongata –breathing, heart & blood vessel activity, digestion, swallowing, vomiting •Transfer info between PNS & CNS Cerebellum • Coordinate movement & balance • Motor skill learning
  • 36. Structure Function Cerebrum • Information processing (learning, emotion, memory, perception, voluntary movement) • Right & Left cerebral hemispheres • Corpus callosum: connect hemispheres Brainstem *Oldest evolutionary part* •Basic, autonomic survival behaviors •Medulla oblongata –breathing, heart & blood vessel activity, digestion, swallowing, vomiting •Transfer info between PNS & CNS Cerebellum • Coordinate movement & balance • Motor skill learning Human Brain
  • 37. Structure Function Cerebrum • Information processing (learning, emotion, memory, perception, voluntary movement) • Right & Left cerebral hemispheres • Corpus callosum: connect hemispheres Brainstem *Oldest evolutionary part* •Basic, autonomic survival behaviors •Medulla oblongata –breathing, heart & blood vessel activity, digestion, swallowing, vomiting •Transfer info between PNS & CNS Cerebellum • Coordinate movement & balance • Motor skill learning Human Brain
  • 38. Structure Function Cerebrum • Information processing (learning, emotion, memory, perception, voluntary movement) • Right & Left cerebral hemispheres • Corpus callosum: connect hemispheres Brainstem *Oldest evolutionary part* •Basic, autonomic survival behaviors •Medulla oblongata –breathing, heart & blood vessel activity, digestion, swallowing, vomiting •Transfer info between PNS & CNS Cerebellum • Coordinate movement & balance • Motor skill learning Human Brain