This document is a transcript of a Twitter discussion using the hashtag #hpm. Various healthcare professionals and patients join to discuss the role of marijuana in palliative care. Participants discuss how marijuana can help with nausea, spasms and appetite for patients with life-threatening illnesses. However, some note it is difficult to balance legitimate medical use versus diversion of other controlled substances. The discussion considers research on marijuana and differences from synthetic THC. State laws around medical marijuana are also discussed.