3D VISUALIZATION OF HUMAN BLOOD CELLS WITH OPEN SOURCE SOFTWARE
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The document outlines the development of 3D models of red blood cells using Blender software to aid in visualizing concepts not visible to the naked eye. It details the technical process, including designing, rendering, and resources utilized like Pixabay and FastStone Image Viewer. The resulting models are intended for educational purposes and can be applied in scientific projects related to biological studies.
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About Red Blood Cells
● Red blood cells, also known as RBCs, red cells,[1] red blood corpuscles, haematids,
erythroid cells or erythrocytes (from Greek erythros for "red" and kytos for "hollow
vessel", with -cyte translated as "cell" in modern usage), are the most common type
of blood cell and the vertebrate's principal means of delivering oxygen (O2) to the
body tissues—via blood flow through the circulatory system.[2] RBCs take up oxygen
in the lungs, or gills of fish, and release it into tissues while squeezing through the
body's capillaries.
● Blood Cells. Archived from the original on 2016-07-23.
https://web.archive.org/web/20160723113019/http://www.biosbcc.net/doohan/sample/htm/Blood%20cells.htm
● Red blood cell. https://en.wikipedia.org/wiki/Red_blood_cell
● Vinay Kumar; Abul K. Abbas; Nelson Fausto; Richard N. Mitchell (2007). Robbins Basic Pathology (8th ed.).
Saunders.](https://image.slidesharecdn.com/3dvisualizationofhumanbloodcellswithopensourcesoftwaredoi-190610053855/85/3D-VISUALIZATION-OF-HUMAN-BLOOD-CELLS-WITH-OPEN-SOURCE-SOFTWARE-5-320.jpg)
3D VISUALIZATION OF HUMAN BLOOD CELLS WITH OPEN SOURCE SOFTWARE
- 1. TRANSILVANIA UNIVERSITY OF BRAȘOV, ROMANIA / UNITBV 10 – 14 June 2019 / Erasmus + Programme 3D VISUALIZATION OF HUMAN BLOOD CELLS WITH OPEN SOURCE SOFTWARE Assoc. Prof. Dr. Eng. Tihomir Dovramadjiev Technical University of Varna, Bulgaria / TUV MTF, Department Industrial Design tihomir.dovramadjiev@tu-varna.bg DOI: 10.13140/RG.2.2.29390.31045 https://www.researchgate.net/publication/333672576_3D_VISUALIZATION_OF_HUMAN_BLOOD_CELLS_WITH_OPEN_SOURCE_SOFTWARE
- 2. 2 Abstract ● In the present work, digital three-dimensional red blood cell models are developed to illustrate the learning content by visual- izing models that are invisible to the human eye. Using one of the leading advanced technologies in 3D graphic design – Blender software, the basic geometry of the models is built, a suitable scene is created and rendered images are made. For the needs of the scene the resources of Pixabay are used, and for the final images the filters and processing tools of the Fast- Stone Image Viewer software are applied.
- 3. 3 Research purposes 1. Optimization of the designing process in Blender 3D software. Cre- ating a Tutorial for developing digital red blood cell models. ● Recommendations for manual design work. Obtaining three-dimen- sional geometry of the developed models; ● Using particle system; ● Application of modifiers; ● Opportunities for visualization (images and animation). 2. Using Pixabay's public resources to build an environment (scene). 3. Creating final images via software Fast Stone Image Viewer.
- 5. 5 About Red Blood Cells ● Red blood cells, also known as RBCs, red cells,[1] red blood corpuscles, haematids, erythroid cells or erythrocytes (from Greek erythros for "red" and kytos for "hollow vessel", with -cyte translated as "cell" in modern usage), are the most common type of blood cell and the vertebrate's principal means of delivering oxygen (O2) to the body tissues—via blood flow through the circulatory system.[2] RBCs take up oxygen in the lungs, or gills of fish, and release it into tissues while squeezing through the body's capillaries. ● Blood Cells. Archived from the original on 2016-07-23. https://web.archive.org/web/20160723113019/http://www.biosbcc.net/doohan/sample/htm/Blood%20cells.htm ● Red blood cell. https://en.wikipedia.org/wiki/Red_blood_cell ● Vinay Kumar; Abul K. Abbas; Nelson Fausto; Richard N. Mitchell (2007). Robbins Basic Pathology (8th ed.). Saunders.
- 6. 6 II. Technical Means & Resources ● Apace OpenOffice. https://www.openoffice.org/ ● Blender Software. https://www.blender.org/ ● FastStone Image Viewer. https://www.faststone.org/ ● Pixabay. https://pixabay.com
- 7. 7 Apace OpenOffice Apace OpenOffice. https://www.openoffice.org/
- 8. 8 Blender software ● Blender Software. https://www.blender.org/
- 9. 9 Blender software / About ● Blender is the free and open source 3D creation suite. It supports the entirety of the 3D pipeline—modeling, rigging, animation, simulation, rendering, compositing and motion tracking, even video editing and game creation. Advanced users employ Blender’s API for Python scripting to customize the application and write specialized tools; often these are included in Blender’s future releases. Blender is well suited to individuals and small studios who benefit from its unified pipeline and responsive development process. Examples from many Blender-based projects are available in the showcase. ● Blender is cross-platform and runs equally well on Linux, Windows, and Macintosh computers. Its interface uses OpenGL to provide a consistent experience. To confirm specific compatibility, the list of supported platforms indicates those regularly tested by the development team. ● As a community-driven project under the GNU General Public License (GPL), the public is empowered to make small and large changes to the code base, which leads to new features, responsive bug fixes, and better usability. Blender has no price tag, but you can invest, participate, and help to advance a powerful collaborative tool: . ● Blender Software. https://www.blender.org/
- 10. 10 Blender software / The license ● Blender is the free and open source 3D creation suite. It supports the entirety of the 3D pipeline—modeling, rigging, animation, simulation, rendering, compositing and motion tracking, even video editing and game creation. Advanced users employ Blender’s API for Python scripting to customize the application and write specialized tools; often these are included in Blender’s future releases. Blender is well suited to individuals and small studios who benefit from its unified pipeline and responsive development process. Examples from many Blender-based projects are available in the showcase. ● Blender is cross-platform and runs equally well on Linux, Windows, and Macintosh computers. Its interface uses OpenGL to provide a consistent experience. To confirm specific compatibility, the list of supported platforms indicates those regularly tested by the development team. ● As a community-driven project under the GNU General Public License (GPL), the public is empowered to make small and large changes to the code base, which leads to new features, responsive bug fixes, and better usability. Blender has no price tag, but you can invest, participate, and help to advance a powerful collaborative tool: . ● Blender Software. https://www.blender.org/
- 11. 11 Blender Funding ● Blender Funding https://www.blender.org/wp-content/uploads/2019/01/blender_funding_2019_01_28.png?x96075
- 12. 12 FastStone Image Viewer ● FastStone Image Viewer. https://www.faststone.org/
- 13. 13 FastStone Image Viewer. Features ● FastStone Image Viewer. https://www.faststone.org/FSViewerDetail.htm Image browser and viewer with a familiar Windows Explorer-like user interface Support of many popular image formats:
- 14. 14 FastStone Image Viewer. Features ● FastStone Image Viewer. https://www.faststone.org/FSViewerDetail.htm True Full Screen viewer with image zoom support and unique fly-out menu panels Crystal-clear and customizable one-click image magnifier Powerful image editing tools: Resize/resample, rotate/flip, crop, sharpen/blur, adjust lighting/colors/curves/levels etc. Eleven re-sampling algorithms to choose from when resizing images Image color effects: gray scale, sepia, negative, Red/Green/Blue adjustment Image special effects: annotation, drop shadow, framing, bump map, sketch, oil painting, lens Draw texts, lines, highlights, rectangles, ovals and callout objects on images Clone Stamp and Healing Brush Superior Red-Eye effect removal/reduction with completely natural looking end result Multi-level Undo/Redo capability One-touch best fit/actual size image display support Image management, including tagging capability, with drag-and-drop and Copy To/Move To Folder support Histogram display with color counter feature Compare images side-by-side (up to 4 at a time) to easily cull those forgettable shots Image EXIF metadata support (plus comment editing for JPEGs) Configurable batch processing to convert/rename large or small collections of images Slideshow creation with 150+ transition effects and music support (MP3, WMA, WAV...) Create efficient image attachment(s) for emailing to family and friends Print images with full page-layout control Create fully configurable Contact Sheets Create memorable artistic image montages from your family photos for personalized desktop wallpapers (Wallpaper Anywhere) Acquire images from scanner. Support batch scanning to PDF, TIFF, JPEG and PNG Versatile screen capture capability Powerful Save As interface to compare image quality and control generated file size Run favorite programs with one keystroke from within Image Viewer Offer portable version of the program which can be run from a removable storage device Configurable mouse wheel support Support program skins Support dual-monitor configurations Support touch interface (tap, swipe, pinch) Support dual instances Play video files (Third party codecs may be required for old versions of Windows) And much more...
- 15. 15 Pixabay ● Pixabay. Stunning free images & royalty free stock https://pixabay.com/
- 16. 16 III. 3D Red Blood Cells Visualization. Tutorial
- 17. 17 Blender Default Interface ● Deleting the default started 3D cube (Object Mode)
- 18. 18 3D Modeling of red blood cell ● Adding 3D Cylinder primitive. Add > Mesh > Cylinder (Object Mode)
- 19. 19 3D Modeling of red blood cell ● Manually scaling the object. (“Z” axis; Object Mode)
- 20. 20 3D Modeling of red blood cell ● The result of 3D transformation
- 21. 21 3D Modeling of red blood cell ● Selecting the top face of the cylinder. (Edit Mode)
- 22. 22 3D Modeling of red blood cell ● Extruding (“E” key) + Scaling (“S” key) the selected face
- 23. 23 3D Modeling of red blood cell ● Transforming the selected face (“Z” axis)
- 24. 24 3D Modeling of red blood cell ● Extruding (“E” key) + Scaling (“S” key) the selected face
- 25. 25 3D Modeling of red blood cell ● Transforming the selected face (“Z” axis)
- 26. 26 3D Modeling of red blood cell ● Inside vision. (Edit Mode; Wireframe)
- 27. 27 Subdivision Surface Modifier ● Applying the subdivision surface modifier. (Object Mode)
- 28. 28 Subdivision Surface Modifier ● Subdivision Surface Modifier: default parameters
- 29. 29 Subdivision Surface Modifier ● Subdivision Surface Modifier. Parameters / Subdivisions: View: 4; Render: 2
- 30. 30 Material ● Adding the material to 3D model of blood cell
- 31. 31 Particles ● Adding the new 3D object – UV Sphere
- 32. 32 Particles ● Selecting UV Sphere. Particle Settings & Type: Emitter
- 33. 33 Particles ● Particles parameters: Render > Object + Dupli Object: 3D blood cell model (cylinder)
- 35. 35 Particles ● Particles parameters: Rotation (Activated) > Random +
- 36. 36 Particles ● Particles parameters / Result Preview
- 37. 37 Particles ● Particles parameters: Render > Size +
- 38. 38 Particles ● Particles parameters: Emission > Number: 200
- 39. 39 Converting to new 3D mesh ● Switching to Modifiers and converting
- 40. 40 Converting to new 3D mesh ● The result: Particles are actual new 3D mesh objects
- 41. 41 The 3D Scene ● Hiding first 3D model of the blood cell
- 42. 42 The 3D Scene ● Hiding 3D model of sphere
- 43. 43 The 3D Scene ● Camera View and parameters
- 44. 44 The 3D Scene ● Render Preview
- 45. 45 Pixabay. The Background ● Adding a background to Blender scene with Pixabay free image: https://pixabay.com/photos/blur-sinister-bug-texture-seawall-1876100/
- 46. 46 FastStone Image Viewer ● FastStone Image Viewer. Preview of working presentation files
- 47. 47 FastStone Image Viewer. Changing the color ● Manually changing the color from light blue to red
- 48. 48 FastStone Image Viewer. Changing the color ● The Result
- 49. 49 Blender. The 3D Scene ● Adding a material / texture to new 3D background sphere
- 50. 50 III. Results
- 51. 51 Results ● Blender Internal Render result (Default options)
- 52. 52 Results ● Final image result (working with FastStone Image Viewer software)
- 53. 53 IV. Conclusion ● In this study, a 3D model of a red blood cell is fully developed. With particles system in Blender, the 3D model is multiplied to create a scene needed to visualize images. Also the ready models can be used for animations and 3D printing (of real samples). The results are applicable both in the educational process and in scientific projects, where the study of biological tissues, cells, atoms, compounds and others is set by assign- ment. The present work is also useful with regard to its technical part, where in sequence are shown details of the construction of the 3D geometry.
- 54. 54 References ● Apace OpenOffice. http://www.openoffice.org/download/ ● Blender Software. https://www.blender.org/ ● Blender Funding https://www.blender.org/wp-content/uploads/2019/01/blender_funding_2019_01_28.png?x96075 ● Blood Cells. Archived from the original on 2016-07-23. https://web.archive.org/web/20160723113019/http://www.biosbcc.net/doohan/sample/htm/Blood%20cells.htm ● FastStone Image Viewer. https://www.faststone.org/ ● Pixabay. https://pixabay.com/ ● Pixabay, Free Image: https://pixabay.com/photos/blur-sinister-bug-texture-seawall-1876100/ ● Red blood cell. https://en.wikipedia.org/wiki/Red_blood_cell ● Tihomir Dovramadjiev PhD. Modern accessible application of the system Blender in 3D design practice. https://www.researchgate.net/publication/312033613_Modern_accessible_application_of_the_system_Blender_in_3D_design_practice ● Tihomir Dovramadjiev PhD. Blender software. 2.79b Version. About, License & Development. DOI: 10.13140/RG.2.2.36167.75687 https://www.researchgate.net/publication/328677236_Blender_software_279b_Version_About_License_Development ● Vinay Kumar; Abul K. Abbas; Nelson Fausto; Richard N. Mitchell (2007). Robbins Basic Pathology (8th ed.). Saunders.