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Processing
       &
Analysis of data
D.A. Asir John Samuel, MPT (Neuro Paed),
 Lecturer, Alva’s college of Physiotherapy,
                 Moodbidri

            Dr.Asir John Samuel (PT), Lecturer, ACP
Processing operations

• Editing

• Coding

• Classification

• Tabulation



                   Dr.Asir John Samuel (PT), Lecturer, ACP
Editing

• Process of examining the collected raw data

• Editing is done to assure that data are
  accurate, consistent with other facts gathered,
  uniformly entered, as complete as possible

• Field editing

• Central editing
                    Dr.Asir John Samuel (PT), Lecturer, ACP
Field editing

• Review of reporting forms by the investigator
  for completing, translating or rewriting

• Individual writing styles

• On the very next day or on the next day

• Not correct errors of omission by simply
  guessing
                  Dr.Asir John Samuel (PT), Lecturer, ACP
Central editing
• Take place when all forms or schedules have
  been completed and returned to fitness

• Correct errors such as an entry in wrong place,
  wrong month, and the like

• Respondent can be contacted for clarification

• No bias

                 Dr.Asir John Samuel (PT), Lecturer, ACP
Coding

• Process of assigning numerals or other
  symbols to answers
• Should be appropriate to research problem
  under consideration
• Necessary for effective analysis
• Extraction of data
                 Dr.Asir John Samuel (PT), Lecturer, ACP
Classification

• Large volume of raw data is reduced into
  homogeneous group
• Arranging data in groups or classes on basis of
  common characteristics
• Classification according to attributes
• Classification according to class-intervals
                  Dr.Asir John Samuel (PT), Lecturer, ACP
Tabulation

• Arranging in concise and logical order

• Summarising raw data and displaying in
  compact form

• Orderly arrangement of data in columns and
  rows


                 Dr.Asir John Samuel (PT), Lecturer, ACP
Tabulation is essential because of

• Conserves space and reduces explanatory and
  descriptive statement to a minimum

• Facilitates process of comparison

• Facilitates summation of items and detection
  of errors and omissions

• Basis for various statistical computations
                 Dr.Asir John Samuel (PT), Lecturer, ACP
Problems in processing

• Problem concerning “Don’t Know” responses

• Use of percentages




                Dr.Asir John Samuel (PT), Lecturer, ACP
Problem concerning “Don’t Know” responses

 • When DK group is small, it is of little significance

 • In big group, it becomes mater of concern

 • Actually may not know the answer or

 • Researcher may fail in obtaining appropriate
   information (failure of questioning process)

 • Keep as a separate category in tabulation
                    Dr.Asir John Samuel (PT), Lecturer, ACP
Use of percentages
• 2/more percentages must not be averaged
  unless each is weighted by group size

• Too large percentages should be avoided
  because difficult to understand and confuse

• Hide base value

• Real differences may not be correctly read

• Can never exceed 100 percent and for decrease
                 Dr.Asir John Samuel (PT), Lecturer, ACP
Statistics in Medical Research

• Documentation of medical history of disease,
  their progression, variability b/w patient,
  association with age, gender, etc.

• Efficacy of various types of therapy

• Definition of normal range

• Epidemiological studies
                 Dr.Asir John Samuel (PT), Lecturer, ACP
Statistics in Medical Research
• Study the effect of environment, socio-
  economic and seasonal factors

• Provide assessment of state health                      in
  common, met and unmet needs

• Success/failure of specific health programme

• Promote health legislation

• Evaluate total health programme of action
                Dr.Asir John Samuel (PT), Lecturer, ACP
Statistics in Medical Research - Limitation

• Does not deal with individual fact

• Conclusion are not exact

• Can be misused

• Common men cannot handle properly



                 Dr.Asir John Samuel (PT), Lecturer, ACP
Normal distribution

• Represented by a family of infinite curves
 defined uniquely by 2 parameter the mean
 and the SD of the population
• The curve are always symmetrically bell
 shaped. The width of the curve is defined by
 population, SD

                  Dr.Asir John Samuel (PT), Lecturer, ACP
Normal distribution
• Mean, median and mode coincide

• It extends from - ∞ to + ∞

• Symmetrically about the mean

• Approx 68% of distribution is within 1SD of
  mean (68.27%)

- 95% - 2SD (1.96 SD)

- 99% - 3SD (2.58 SD)
                Dr.Asir John Samuel (PT), Lecturer, ACP
Normal distribution
• The total area under the curve is 1

• The value of measure of skewness is zero. It is
  not skewed

• The curve is asymptotic. It approaches but
  never touches baseline at extremes

• The curve extends on the both sides -3σ
  distance on left to +3σ distance on the right
                 Dr.Asir John Samuel (PT), Lecturer, ACP
Normal distribution - Uses

• Construct confidence interval

• Many     statistical           techniques                 makes   an
  underlying assumption of normality

• Distribution of sample means is normal

• Normality is important in statistical inference

                  Dr.Asir John Samuel (PT), Lecturer, ACP
Skewness
• Measure of lack of symmetry in a distribution

• Positive skewed

- Right tail is longer

- Mass of distribution is concentrated on left
  side

- Distribution is said to be right skewed
                  Dr.Asir John Samuel (PT), Lecturer, ACP
Negative skewed

• Left tail is longer

• Mass of distribution concentration on right
  side

• Distribution is said to be left skewed

• Value of skewness is 0 for normal distribution

                   Dr.Asir John Samuel (PT), Lecturer, ACP
Kurtosis

• Measure of degree of peakness in distribution

• For normal distribution, value of kurtosis is 3

• Leptokurtic – High peakness

• Mesokurtic – normal

• Platykurtic – Low peakness

                 Dr.Asir John Samuel (PT), Lecturer, ACP
Descriptive statistics

• Measures of location

- Central tendency

- Mean, median and mode

• Measures of variation

- Dispersion

- Range, quartile, IQR, variance and SD
                 Dr.Asir John Samuel (PT), Lecturer, ACP
Mean

• Sum of all observation divided by total no. of
  observation




                Dr.Asir John Samuel (PT), Lecturer, ACP
Mean - merits

• Well understood by most people

• Computation of mean is easy

• More stable

• All items in a series are taken into account

• Used in further statistical calculation

• Good basis for comparison
                  Dr.Asir John Samuel (PT), Lecturer, ACP
Mean - Demerits

• Affected by extreme values

• Cannot be computed by mere observation

• Not suitable for skewed distribution

• May not be an actual item

• Not in qualitative data

                 Dr.Asir John Samuel (PT), Lecturer, ACP
Median

• Middle most observation when data is
 arranged in ascending/descending order of
 magnitude

• Divides number into 2 halves such that no.of
 items below it is same as no.of items above


                Dr.Asir John Samuel (PT), Lecturer, ACP
Median


    Odd = n+1/2



Even = n/2 + (n+1)/2
                          2


  Dr.Asir John Samuel (PT), Lecturer, ACP
Median - Merits

• Widely used measures of CD

• Not influenced by extreme values

• Can be determined if extremes are not known

• Not a typical representation of series

• Useful for skewed distribution

                 Dr.Asir John Samuel (PT), Lecturer, ACP
Median - Demerits

• When no. of items are small, median may not
  be representative

• It is effected by frequency of neighboring
  items

• Not a typical representation of series


                 Dr.Asir John Samuel (PT), Lecturer, ACP
Mode

• Most frequently occurring observation in data

• If all values are different then no mode




                 Dr.Asir John Samuel (PT), Lecturer, ACP
Mode - Merits

• Can be computed by mere observation

• Simple

• Precise

• Less time consuming

• Less strain

                 Dr.Asir John Samuel (PT), Lecturer, ACP
Mode - Demerits

• Not an      amenable to                           further algebraic
  treatment

• Not rigidly defined

• Affected by no. of frequency of items



                 Dr.Asir John Samuel (PT), Lecturer, ACP
Measures of Dispersion (variation)

• Range

• Interquartile range

• Variance

• Standard Deviation



                 Dr.Asir John Samuel (PT), Lecturer, ACP
Range

• Difference between largest and smallest value



       Range = Largest no. – Smallest no.




                Dr.Asir John Samuel (PT), Lecturer, ACP
Quartile

• Value that divide data into 4 equal parts when
  data is arranged in ascending order

       Q1 = (n+1/4)th ordered observation

     Q1 = [2(n+1)/4]th ordered observation

     Q3 = [3(n+1)/4]th ordered observation

                Dr.Asir John Samuel (PT), Lecturer, ACP
Interquartile range

• Provides range which covers middlemost 50%
 of observation

• Good measures of dispersion if there are
 extreme values


                   IQR = Q3 – Q1

                  Dr.Asir John Samuel (PT), Lecturer, ACP
Variance

• Sum of squares of difference of each
 observation from mean, divided by n-1



                                         𝜀 𝑥−𝑥 2
             Variance =
                                           𝑛−1



               Dr.Asir John Samuel (PT), Lecturer, ACP
Variance - Merits

• Easy to calculate

• Indicate the variability clearly

• Most informative




                  Dr.Asir John Samuel (PT), Lecturer, ACP
Variance - Demerits
• Units of expression of variance is not the same




                 Dr.Asir John Samuel (PT), Lecturer, ACP
Standard Deviation (SD)

• Square root of variance



                                𝜀 𝑥−𝑥 2
                 SD =         √
                                  𝑛−1




                Dr.Asir John Samuel (PT), Lecturer, ACP
Standard Deviation - Merits

• Most widely used

• Used in calculating standard error




                 Dr.Asir John Samuel (PT), Lecturer, ACP
Standard Deviation -Demerits

• Lengthy process

• Gives weightage to only extreme valves




                Dr.Asir John Samuel (PT), Lecturer, ACP

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8.processing

  • 1. Processing & Analysis of data D.A. Asir John Samuel, MPT (Neuro Paed), Lecturer, Alva’s college of Physiotherapy, Moodbidri Dr.Asir John Samuel (PT), Lecturer, ACP
  • 2. Processing operations • Editing • Coding • Classification • Tabulation Dr.Asir John Samuel (PT), Lecturer, ACP
  • 3. Editing • Process of examining the collected raw data • Editing is done to assure that data are accurate, consistent with other facts gathered, uniformly entered, as complete as possible • Field editing • Central editing Dr.Asir John Samuel (PT), Lecturer, ACP
  • 4. Field editing • Review of reporting forms by the investigator for completing, translating or rewriting • Individual writing styles • On the very next day or on the next day • Not correct errors of omission by simply guessing Dr.Asir John Samuel (PT), Lecturer, ACP
  • 5. Central editing • Take place when all forms or schedules have been completed and returned to fitness • Correct errors such as an entry in wrong place, wrong month, and the like • Respondent can be contacted for clarification • No bias Dr.Asir John Samuel (PT), Lecturer, ACP
  • 6. Coding • Process of assigning numerals or other symbols to answers • Should be appropriate to research problem under consideration • Necessary for effective analysis • Extraction of data Dr.Asir John Samuel (PT), Lecturer, ACP
  • 7. Classification • Large volume of raw data is reduced into homogeneous group • Arranging data in groups or classes on basis of common characteristics • Classification according to attributes • Classification according to class-intervals Dr.Asir John Samuel (PT), Lecturer, ACP
  • 8. Tabulation • Arranging in concise and logical order • Summarising raw data and displaying in compact form • Orderly arrangement of data in columns and rows Dr.Asir John Samuel (PT), Lecturer, ACP
  • 9. Tabulation is essential because of • Conserves space and reduces explanatory and descriptive statement to a minimum • Facilitates process of comparison • Facilitates summation of items and detection of errors and omissions • Basis for various statistical computations Dr.Asir John Samuel (PT), Lecturer, ACP
  • 10. Problems in processing • Problem concerning “Don’t Know” responses • Use of percentages Dr.Asir John Samuel (PT), Lecturer, ACP
  • 11. Problem concerning “Don’t Know” responses • When DK group is small, it is of little significance • In big group, it becomes mater of concern • Actually may not know the answer or • Researcher may fail in obtaining appropriate information (failure of questioning process) • Keep as a separate category in tabulation Dr.Asir John Samuel (PT), Lecturer, ACP
  • 12. Use of percentages • 2/more percentages must not be averaged unless each is weighted by group size • Too large percentages should be avoided because difficult to understand and confuse • Hide base value • Real differences may not be correctly read • Can never exceed 100 percent and for decrease Dr.Asir John Samuel (PT), Lecturer, ACP
  • 13. Statistics in Medical Research • Documentation of medical history of disease, their progression, variability b/w patient, association with age, gender, etc. • Efficacy of various types of therapy • Definition of normal range • Epidemiological studies Dr.Asir John Samuel (PT), Lecturer, ACP
  • 14. Statistics in Medical Research • Study the effect of environment, socio- economic and seasonal factors • Provide assessment of state health in common, met and unmet needs • Success/failure of specific health programme • Promote health legislation • Evaluate total health programme of action Dr.Asir John Samuel (PT), Lecturer, ACP
  • 15. Statistics in Medical Research - Limitation • Does not deal with individual fact • Conclusion are not exact • Can be misused • Common men cannot handle properly Dr.Asir John Samuel (PT), Lecturer, ACP
  • 16. Normal distribution • Represented by a family of infinite curves defined uniquely by 2 parameter the mean and the SD of the population • The curve are always symmetrically bell shaped. The width of the curve is defined by population, SD Dr.Asir John Samuel (PT), Lecturer, ACP
  • 17. Normal distribution • Mean, median and mode coincide • It extends from - ∞ to + ∞ • Symmetrically about the mean • Approx 68% of distribution is within 1SD of mean (68.27%) - 95% - 2SD (1.96 SD) - 99% - 3SD (2.58 SD) Dr.Asir John Samuel (PT), Lecturer, ACP
  • 18. Normal distribution • The total area under the curve is 1 • The value of measure of skewness is zero. It is not skewed • The curve is asymptotic. It approaches but never touches baseline at extremes • The curve extends on the both sides -3σ distance on left to +3σ distance on the right Dr.Asir John Samuel (PT), Lecturer, ACP
  • 19. Normal distribution - Uses • Construct confidence interval • Many statistical techniques makes an underlying assumption of normality • Distribution of sample means is normal • Normality is important in statistical inference Dr.Asir John Samuel (PT), Lecturer, ACP
  • 20. Skewness • Measure of lack of symmetry in a distribution • Positive skewed - Right tail is longer - Mass of distribution is concentrated on left side - Distribution is said to be right skewed Dr.Asir John Samuel (PT), Lecturer, ACP
  • 21. Negative skewed • Left tail is longer • Mass of distribution concentration on right side • Distribution is said to be left skewed • Value of skewness is 0 for normal distribution Dr.Asir John Samuel (PT), Lecturer, ACP
  • 22. Kurtosis • Measure of degree of peakness in distribution • For normal distribution, value of kurtosis is 3 • Leptokurtic – High peakness • Mesokurtic – normal • Platykurtic – Low peakness Dr.Asir John Samuel (PT), Lecturer, ACP
  • 23. Descriptive statistics • Measures of location - Central tendency - Mean, median and mode • Measures of variation - Dispersion - Range, quartile, IQR, variance and SD Dr.Asir John Samuel (PT), Lecturer, ACP
  • 24. Mean • Sum of all observation divided by total no. of observation Dr.Asir John Samuel (PT), Lecturer, ACP
  • 25. Mean - merits • Well understood by most people • Computation of mean is easy • More stable • All items in a series are taken into account • Used in further statistical calculation • Good basis for comparison Dr.Asir John Samuel (PT), Lecturer, ACP
  • 26. Mean - Demerits • Affected by extreme values • Cannot be computed by mere observation • Not suitable for skewed distribution • May not be an actual item • Not in qualitative data Dr.Asir John Samuel (PT), Lecturer, ACP
  • 27. Median • Middle most observation when data is arranged in ascending/descending order of magnitude • Divides number into 2 halves such that no.of items below it is same as no.of items above Dr.Asir John Samuel (PT), Lecturer, ACP
  • 28. Median Odd = n+1/2 Even = n/2 + (n+1)/2 2 Dr.Asir John Samuel (PT), Lecturer, ACP
  • 29. Median - Merits • Widely used measures of CD • Not influenced by extreme values • Can be determined if extremes are not known • Not a typical representation of series • Useful for skewed distribution Dr.Asir John Samuel (PT), Lecturer, ACP
  • 30. Median - Demerits • When no. of items are small, median may not be representative • It is effected by frequency of neighboring items • Not a typical representation of series Dr.Asir John Samuel (PT), Lecturer, ACP
  • 31. Mode • Most frequently occurring observation in data • If all values are different then no mode Dr.Asir John Samuel (PT), Lecturer, ACP
  • 32. Mode - Merits • Can be computed by mere observation • Simple • Precise • Less time consuming • Less strain Dr.Asir John Samuel (PT), Lecturer, ACP
  • 33. Mode - Demerits • Not an amenable to further algebraic treatment • Not rigidly defined • Affected by no. of frequency of items Dr.Asir John Samuel (PT), Lecturer, ACP
  • 34. Measures of Dispersion (variation) • Range • Interquartile range • Variance • Standard Deviation Dr.Asir John Samuel (PT), Lecturer, ACP
  • 35. Range • Difference between largest and smallest value Range = Largest no. – Smallest no. Dr.Asir John Samuel (PT), Lecturer, ACP
  • 36. Quartile • Value that divide data into 4 equal parts when data is arranged in ascending order Q1 = (n+1/4)th ordered observation Q1 = [2(n+1)/4]th ordered observation Q3 = [3(n+1)/4]th ordered observation Dr.Asir John Samuel (PT), Lecturer, ACP
  • 37. Interquartile range • Provides range which covers middlemost 50% of observation • Good measures of dispersion if there are extreme values IQR = Q3 – Q1 Dr.Asir John Samuel (PT), Lecturer, ACP
  • 38. Variance • Sum of squares of difference of each observation from mean, divided by n-1 𝜀 𝑥−𝑥 2 Variance = 𝑛−1 Dr.Asir John Samuel (PT), Lecturer, ACP
  • 39. Variance - Merits • Easy to calculate • Indicate the variability clearly • Most informative Dr.Asir John Samuel (PT), Lecturer, ACP
  • 40. Variance - Demerits • Units of expression of variance is not the same Dr.Asir John Samuel (PT), Lecturer, ACP
  • 41. Standard Deviation (SD) • Square root of variance 𝜀 𝑥−𝑥 2 SD = √ 𝑛−1 Dr.Asir John Samuel (PT), Lecturer, ACP
  • 42. Standard Deviation - Merits • Most widely used • Used in calculating standard error Dr.Asir John Samuel (PT), Lecturer, ACP
  • 43. Standard Deviation -Demerits • Lengthy process • Gives weightage to only extreme valves Dr.Asir John Samuel (PT), Lecturer, ACP