This document outlines a guidebook for designing learning scenarios in initial teacher education. It discusses the TEL@FTELAB project which aims to support pre-service teachers in developing technology-enhanced learning scenarios. The guidebook takes teachers through a 4-phase process for designing, implementing, and evaluating learning scenarios which incorporate 21st century skills. Currently, the guidebook is being used and tested by pre-service teachers in Portugal who are developing learning scenarios and implementing them in secondary schools. The goal is to continuously improve the guidebook and make an English version available online to support teachers internationally.