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A Multifaceted Approach
in Reducing Healthcare
Pathogens
By Dr. Christopher Truitt
Chief Science Officer of, GERMBLAST
Disclosure
“Nightmare bacteria”
are trying
to spread in
the U.S., CDC says
https://www.nbcnews.com/health/health-news/nightmare-bacteria-are-trying-spread-u-s-cdc-says-n862436
“The Flu Season
Is the Worst in
Nearly a Decade”
https://www.nytimes.com/2018/01/26/health/flu-rates-deaths.html
Recent Headlines!
Importance:
• 722,000 occurrences in 2011 in acute care hospitals
• Approximately 75,000 deaths
• Estimated cost of $9.8 billon (2012 dollars)
Any given day 1 in 25 patients have at least
one Healthcare-Associated Infection!
Magill SS et al. N Engl J Med. 2014; 370:1198-1208.
Zimlichman E et al. AMA Intern Med 2013; 173:2039-2046.
The Problem: Healthcare-
Associated Infections
Sources of Pathogens Causing
HAIs
1. Weinstein RA. Am J Med. 1991; 91:(Suppl 3B):179S-184S.
2. Hayden et al. Infect Control Hosp Epidemiol. 2008; 29:149-154.
3. Stiefel et al. Infect Control Hosp Epidemiol. 2011; 32:185-187.
4. Guerrero et al. Am J Infect Control. 2012; 40:556-558.
Reservoirs1
• Endogenous microflora- approx. 50%
• Cross infection via hands of healthcare personnel
(HCP)- approx. 30%
• Environmental surfaces- approx. 20%
Potential Contamination from HCP
• 52% acquired VRE on hands2
• 45% acquired MRSA on hands3
• 50% acquired C. difficile on hands4
Increased HAI Acquisition Risk
from Prior Room Occupant
0% 100% 200% 300% 400%
Huang
Hardy
Dress
Shaugnessy
Datta
Nseir
Nseir
MRSA
MRSA
C. difficile
MRSA
Pseudomonas
Acinetobacter
Mean = 120%
Increased Risk of Acquisition (%)
Carling P et al. Am J Infect Control. 2013 Nov; 41:S20-S25.
VRE
Thoroughness of Environmental Cleaning
in Multiple Health Care Settings
Carling P et al. Am J Infect Control. 2013 Nov; 41:S20-S25.
Mean 42%
Survival Rate of Pathogens
Pathogen Survival
C. difficile Months - Years
VRE Weeks
MRSA Weeks
Acinetobacter spp. Weeks-Months
Klebsiella Days
Otter and French. J Clin Microbiol 2009; 47:205-207.
Wagenvoort et al. J Hops Infect 2011; 77:282-283.
“Given the choice of improving technology
or improving human behavior, technology
is the better choice.”
Dr. Weinstein 1998
Weinstein RA. Emerg Infect Dis. 1998; 4:416-420.
The Solution: Multifaceted
Approach
Environmental
Disinfection
Staff Education/
Training
Stakeholder
Awareness
Data Collection/
Analysis
Microfiber breaks down biofilms and physically
removes dirt and microbes
Embedded with silver or copper ions to enhance
antimicrobial properties of fiber
Environmental Disinfection-
Microfiber
Focus on high contact areas from multiple users
Common areas:
• Door knobs or push plates, chairs, sinks, fixtures, desks,
railings, OR suites, nursing stations, etc.
Uncommon areas:
• IV Poles, dispensers, and Kleenex boxes
A targeted disinfectant cleaning approach can
significantly decrease the spread of disease from the
environment
Critical Touch Points
Emerging Technologies
Tablets/Phone Disinfection
UV Light
Chemicals
Steam
Aerosolized Hydrogen Peroxide
Biostatic Polymers
Photocatalytic Oxidation (PCO)
When innovative technology is combined with traditional cleaning
practices, the result is a high level of disinfection
Environmental Disinfection- Potential
Results
Data Collection and Analysis
Adenosine Triphosphate
(ATP) Sampling
• Quantitative rapid results
• Can be linked to data
tracking software
• Provides quantitative data
to make decisions prior to
any illness or outbreak
Environmental ATP Data
Allows analysis over
time to find areas for
improvement
Useful to improve
training
Eliminates
opportunities for
illness/infection
0
125
250
375
500
RelativeLightUnits(RLU)
Average ATP Data
Environmental Data Use
Allows detection of high
environmental values
• Improper disinfection
process
• Personel changes
Ability to respond to
abnormal values quicker,
potentially preventing
unwanted illness
134
157
187
132
256
149
0
65
130
195
260
325
RelativeLightUnits(RLU)
Average ATP Data
Staff Education
Hand Hygiene
Proper Chemical
Usage
Antimicrobial
Stewardship
Chain of
Infection
Stakeholder Awareness
Creating an awareness within all stakeholders that each play a
role in keeping the fight outside the body
Questions

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A Multifaceted Approach in Reducing Healthcare Pathogens

  • 1. A Multifaceted Approach in Reducing Healthcare Pathogens By Dr. Christopher Truitt
  • 2. Chief Science Officer of, GERMBLAST Disclosure
  • 3. “Nightmare bacteria” are trying to spread in the U.S., CDC says https://www.nbcnews.com/health/health-news/nightmare-bacteria-are-trying-spread-u-s-cdc-says-n862436 “The Flu Season Is the Worst in Nearly a Decade” https://www.nytimes.com/2018/01/26/health/flu-rates-deaths.html Recent Headlines!
  • 4. Importance: • 722,000 occurrences in 2011 in acute care hospitals • Approximately 75,000 deaths • Estimated cost of $9.8 billon (2012 dollars) Any given day 1 in 25 patients have at least one Healthcare-Associated Infection! Magill SS et al. N Engl J Med. 2014; 370:1198-1208. Zimlichman E et al. AMA Intern Med 2013; 173:2039-2046. The Problem: Healthcare- Associated Infections
  • 5. Sources of Pathogens Causing HAIs 1. Weinstein RA. Am J Med. 1991; 91:(Suppl 3B):179S-184S. 2. Hayden et al. Infect Control Hosp Epidemiol. 2008; 29:149-154. 3. Stiefel et al. Infect Control Hosp Epidemiol. 2011; 32:185-187. 4. Guerrero et al. Am J Infect Control. 2012; 40:556-558. Reservoirs1 • Endogenous microflora- approx. 50% • Cross infection via hands of healthcare personnel (HCP)- approx. 30% • Environmental surfaces- approx. 20% Potential Contamination from HCP • 52% acquired VRE on hands2 • 45% acquired MRSA on hands3 • 50% acquired C. difficile on hands4
  • 6. Increased HAI Acquisition Risk from Prior Room Occupant 0% 100% 200% 300% 400% Huang Hardy Dress Shaugnessy Datta Nseir Nseir MRSA MRSA C. difficile MRSA Pseudomonas Acinetobacter Mean = 120% Increased Risk of Acquisition (%) Carling P et al. Am J Infect Control. 2013 Nov; 41:S20-S25. VRE
  • 7. Thoroughness of Environmental Cleaning in Multiple Health Care Settings Carling P et al. Am J Infect Control. 2013 Nov; 41:S20-S25. Mean 42%
  • 8. Survival Rate of Pathogens Pathogen Survival C. difficile Months - Years VRE Weeks MRSA Weeks Acinetobacter spp. Weeks-Months Klebsiella Days Otter and French. J Clin Microbiol 2009; 47:205-207. Wagenvoort et al. J Hops Infect 2011; 77:282-283.
  • 9. “Given the choice of improving technology or improving human behavior, technology is the better choice.” Dr. Weinstein 1998 Weinstein RA. Emerg Infect Dis. 1998; 4:416-420.
  • 10. The Solution: Multifaceted Approach Environmental Disinfection Staff Education/ Training Stakeholder Awareness Data Collection/ Analysis
  • 11. Microfiber breaks down biofilms and physically removes dirt and microbes Embedded with silver or copper ions to enhance antimicrobial properties of fiber Environmental Disinfection- Microfiber
  • 12. Focus on high contact areas from multiple users Common areas: • Door knobs or push plates, chairs, sinks, fixtures, desks, railings, OR suites, nursing stations, etc. Uncommon areas: • IV Poles, dispensers, and Kleenex boxes A targeted disinfectant cleaning approach can significantly decrease the spread of disease from the environment Critical Touch Points
  • 13. Emerging Technologies Tablets/Phone Disinfection UV Light Chemicals Steam Aerosolized Hydrogen Peroxide Biostatic Polymers Photocatalytic Oxidation (PCO)
  • 14. When innovative technology is combined with traditional cleaning practices, the result is a high level of disinfection Environmental Disinfection- Potential Results
  • 15. Data Collection and Analysis Adenosine Triphosphate (ATP) Sampling • Quantitative rapid results • Can be linked to data tracking software • Provides quantitative data to make decisions prior to any illness or outbreak
  • 16. Environmental ATP Data Allows analysis over time to find areas for improvement Useful to improve training Eliminates opportunities for illness/infection 0 125 250 375 500 RelativeLightUnits(RLU) Average ATP Data
  • 17. Environmental Data Use Allows detection of high environmental values • Improper disinfection process • Personel changes Ability to respond to abnormal values quicker, potentially preventing unwanted illness 134 157 187 132 256 149 0 65 130 195 260 325 RelativeLightUnits(RLU) Average ATP Data
  • 18. Staff Education Hand Hygiene Proper Chemical Usage Antimicrobial Stewardship Chain of Infection
  • 19. Stakeholder Awareness Creating an awareness within all stakeholders that each play a role in keeping the fight outside the body