A presentation on lipids and their classification
- 1. LIPIDS Jaya Upraity B.Voc (F.P.& P.) 3rd year
- 2. “Lipids are organic compounds that contain hydrogen, carbon, and oxygen atoms, which forms the framework for the structure and function of living cells.” In the human body, these molecules can be synthesized in the liver and are found in oil, butter, whole milk, cheese, fried foods and also in some red meats. Introduction
- 4. Lipids are a family of organic compounds, composed of fats and oils. These molecules yield high energy and are responsible for different functions within the human body. Listed below are some important characteristics of Lipids. Lipids are oily or greasy nonpolar molecules, stored in the adipose tissue of the body. Lipids are a heterogeneous group of compounds, mainly composed of hydrocarbon chains. Lipids are energy-rich organic molecules, which provide energy for different life processes. Properties of Lipids
- 5. Lipids are energy-rich organic molecules, which provide energy for different life processes Lipids are a class of compounds characterised by their solubility in nonpolar solvents and insolubility in water. Lipids are significant in biological systems as they form a mechanical barrier dividing a cell from the external environment known as the cell membrane. Continue…
- 6. Lipids are the polymers of fatty acids that contain a long, non-polar hydrocarbon chain with a small polar region containing oxygen. The lipid structure is explained in the diagram below: Lipid Structure
- 7. Within these two major classes of lipids, there are numerous specific types of lipids important to live, including fatty acids, triglycerides, glycerophospholipids, sphingolipids and steroids. These are broadly classified as simple lipids and complex lipids. Classification of Lipids
- 8. Esters of fatty acids with various alcohols. Fats: Esters of fatty acids with glycerol. Oils are fats in the liquid state Waxes: Esters of fatty acids with higher molecular weight monohydric alcohols Simple Lipids
- 9. Esters of fatty acids containing groups in addition to alcohol and a fatty acid. Phospholipids: These are lipids containing, in addition to fatty acids and alcohol, a phosphoric acid residue. They frequently have nitrogen-containing bases and other substituents, eg, in glycerophospholipids the alcohol is glycerol and in sphingophospholipids the alcohol is sphingosine. Glycolipids (glycosphingolipids): Lipids containing a fatty acid, sphingosine and carbohydrate. Other complex lipids: Lipids such as sulfolipids and amino lipids. Lipoproteins may also be placed in this category. Complex Lipids
- 10. These include fatty acids, glycerol, steroids, other alcohols, fatty aldehydes, and ketone bodies, hydrocarbons, lipid-soluble vitamins, and hormones. Because they are uncharged, acylglycerols (glycerides), cholesterol, and cholesteryl esters are termed neutral lipids. These compounds are produced by the hydrolysis of simple and complex lipids. Some of the different types of lipids are described below in detail. Precursor and Derived Lipids
- 11. Fatty acids are carboxylic acids (or organic acid), usually with long aliphatic tails (long chains), either unsaturated or saturated. Saturated fatty acids Lack of carbon-carbon double bonds indicate that the fatty acid is saturated. The saturated fatty acids have higher melting points compared to unsaturated acids of the corresponding size due to their ability to pack their molecules together thus leading to a straight rod-like shape. Fatty Acids
- 12. Unsaturated fatty acids Unsaturated fatty acid is indicated when a fatty acid has more than one double bond. “Often, naturally occurring fatty acids possesses an even number of carbon atoms and are unbranched.” On the other hand, unsaturated fatty acids contain a cis-double bond(s) which create a structural kink that disables them to group their molecules in straight rod-like shape. Continue…
- 13. Fats play several major roles in our body. Some of the important roles of fats are mentioned below: Fats in the correct amounts are necessary for the proper functioning of our body. Many fat-soluble vitamins need to be associated with fats in order to be effectively absorbed by the body. They also provide insulation to the body. They are an efficient way to store energy for longer periods. Role of Fats
- 14. Waxes are “esters” (an organic compound made by replacing the hydrogen with acid by an alkyl or another organic group) formed from long-alcohols and long-chain carboxylic acids. Waxes are found almost everywhere. The fruits and leaves of many plants possess waxy coatings, that can safeguard them from small predators and dehydration. Fur of a few animals and the feathers of birds possess the same coatings serving as water repellants. Carnauba wax is known for its water resistance and toughness (significant for car wax). Waxes
- 15. Membranes are primarily composed of phospholipids that are Phosphoacylglycerols. Triacylglycerols and phosphoacylglycerols are the same, but, the terminal OH group of the phosphoacylglycerol is esterified with phosphoric acid in place of fatty acid which results in the formation of phosphatidic acid. The name phospholipid is derived from the fact that phosphoacylglycerols are lipids containing a phosphate group. Phospholipids
- 16. Our bodies possess chemical messengers known as hormones, which are basically organic compounds synthesized in glands and transported by the bloodstream to various tissues in order to trigger or hinder the desired process. Steroids are a kind of hormone that is typically recognized by their tetracyclic skeleton, composed of three fused six-membered and one five-membered ring, as seen above. The four rings are assigned as A, B, C & D as observed in the shade blue, while the numbers in red indicate the carbons. Steroids
- 17. Cholesterol is a wax-like substance, found only in animal source foods. Triglycerides, LDL, HDL, VLDL are different types of cholesterol found in the blood cells. Cholesterol is an important lipid found in the cell membrane. It is a sterol, which means that cholesterol is a combination of steroid and alcohol. In the human body, cholesterol is synthesized in the liver. These compounds are biosynthesized by all living cells and are essential for the structural component of the cell membrane. Cholesterol
- 18. In the cell membrane, the steroid ring structure of cholesterol provides a rigid hydrophobic structure that helps boost the rigidity of the cell membrane. Without cholesterol, the cell membrane would be too fluid. It is an important component of cell membranes and is also the basis for the synthesis of other steroids, including the sex hormones estradiol and testosterone, as well as other steroids such as cortisone and vitamin D. Continue…