This document describes a project to accelerate a stochastic disease spread simulation algorithm by implementing it on an FPGA system. It first designs a MATLAB simulation of a basic Susceptible-Infected-Recovered (SIR) disease model. It then implements the algorithm on three FPGAs using a hardware-compatible discrete version. The FPGA implementation generates random networks using MATLAB and displays results on a VGA screen in real-time. Verification shows the FPGA results match the MATLAB simulation, validating the hardware implementation.