Amputation is the complete removal of an injured or deformed body part. It is indicated for conditions like peripheral vascular disease, infection, trauma, tumors and diabetes. The goals of amputation are to remove diseased tissue, reduce morbidity/mortality, and allow for maximum independent function with prosthetics. Determining the appropriate amputation level considers factors like circulation, soft tissues, bone/joint condition and infection control. Techniques aim to debride nonviable tissue, close wounds primarily or with flaps/grafts, smooth bone edges and allow for rapid rehabilitation. Complications include non-healing, infection, phantom pain/sensation and contractures.