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Unstable Angina
BRAJESH LAHRI
FINAL PROFESSIONAL MBBS
ALL INDIA INSTITUTE OF MEDICAL
SCIENCES(AIIMS),BHOPAL
Introduction
 A form of Ischemic Heart Disease (IHD)
 IHD can be divided into two groups
 Unstable Angina (UA) is a part of Acute Coronary Syndrome (ACS)
Chronic
Coronary
Artery
Disease
Acute
Coronary
Syndromes
Definition
 Unstable Angina (UA) can be defined as angina pectoris or equivalent
ischemic discomfort with presence of any one of the following features :
 It occurs at rest or with minimal exertion and lasts more than 10 minutes
 It is severe in nature and acute in onset
 Attacks are more severe ,prolonged and frequent than previous attacks
(Also known as Crescendo Pattern)
Etiopathogenesis
 Ischemic Heart Disease  Key Problem  Decreased Blood Supply to Myocardium (i.e.
Myocardial ischemia)
Decreased Myocardial
Oxygen Supply (Ex:
Partial/Complete Occlusion
of Blood vessel lumen,
Coronary artery spasm)
Increased Myocardial
Oxygen Demand (Ex: Physical
activity , Emotional
Excitement)
Myocardial
Ischemia
Angina
Flowchart depicting
pathogenesis of Acute Coronary
artery disease i.e. Unstable
Angina
Risk Factors
 Hypertension
 Smoking
 Hereditary factors
 Diabetes
 Dyslipidemia
 Obesity
Clinical Manifestations
 CHEST PAIN( May radiate to SHOULDER,
ARM,JAW,NECK,BACK)
 CHEST DISCOMFORT THAT FEELS LIKE
TIGHTNESS, SQUEEZING, CRUSHING,
BURNING)
 SHORTNESS OF BREATH
 SWEATING
Diagnostic Evaluation
Clinical History
Electrocardiogr
am (ECG)
Cardiac
Markers
Stress Testing
Diagnostic Evaluation
Management
Management
Medical
Management
Surgical
Management
MEDICAL MANAGEMENT
 Blood thinners (antiplatelet drugs) are used to treat and prevent unstable angina.
 These medicines may be able to reduce the chance of a heart attack or the
severity of a heart attack that occurs.
 During an unstable angina event:
 Patient is given heparin (or another blood thinner) and nitroglycerin (under the
tongue or through an IV)
 Other treatments may include medicines to control blood pressure,
anxiety, abnormal heart rhythms, and cholesterol (such as a statin drug)
SURGICAL MANAGEMENT
 Early coronary angiography and revascularization are the main aims of surgical
management of Unstable angina.
 Either Per Cutaneous angioplasty (PCA) or Coronary artery bypass graft (CABG) is
the treatment of choice for high risk patient with unstable angina.
An Overview of Unstable angina

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An Overview of Unstable angina

  • 1. Unstable Angina BRAJESH LAHRI FINAL PROFESSIONAL MBBS ALL INDIA INSTITUTE OF MEDICAL SCIENCES(AIIMS),BHOPAL
  • 2. Introduction  A form of Ischemic Heart Disease (IHD)  IHD can be divided into two groups  Unstable Angina (UA) is a part of Acute Coronary Syndrome (ACS) Chronic Coronary Artery Disease Acute Coronary Syndromes
  • 3. Definition  Unstable Angina (UA) can be defined as angina pectoris or equivalent ischemic discomfort with presence of any one of the following features :  It occurs at rest or with minimal exertion and lasts more than 10 minutes  It is severe in nature and acute in onset  Attacks are more severe ,prolonged and frequent than previous attacks (Also known as Crescendo Pattern)
  • 4. Etiopathogenesis  Ischemic Heart Disease  Key Problem  Decreased Blood Supply to Myocardium (i.e. Myocardial ischemia) Decreased Myocardial Oxygen Supply (Ex: Partial/Complete Occlusion of Blood vessel lumen, Coronary artery spasm) Increased Myocardial Oxygen Demand (Ex: Physical activity , Emotional Excitement) Myocardial Ischemia Angina
  • 5. Flowchart depicting pathogenesis of Acute Coronary artery disease i.e. Unstable Angina
  • 6. Risk Factors  Hypertension  Smoking  Hereditary factors  Diabetes  Dyslipidemia  Obesity
  • 7. Clinical Manifestations  CHEST PAIN( May radiate to SHOULDER, ARM,JAW,NECK,BACK)  CHEST DISCOMFORT THAT FEELS LIKE TIGHTNESS, SQUEEZING, CRUSHING, BURNING)  SHORTNESS OF BREATH  SWEATING
  • 8. Diagnostic Evaluation Clinical History Electrocardiogr am (ECG) Cardiac Markers Stress Testing
  • 11. MEDICAL MANAGEMENT  Blood thinners (antiplatelet drugs) are used to treat and prevent unstable angina.  These medicines may be able to reduce the chance of a heart attack or the severity of a heart attack that occurs.  During an unstable angina event:  Patient is given heparin (or another blood thinner) and nitroglycerin (under the tongue or through an IV)  Other treatments may include medicines to control blood pressure, anxiety, abnormal heart rhythms, and cholesterol (such as a statin drug)
  • 12. SURGICAL MANAGEMENT  Early coronary angiography and revascularization are the main aims of surgical management of Unstable angina.  Either Per Cutaneous angioplasty (PCA) or Coronary artery bypass graft (CABG) is the treatment of choice for high risk patient with unstable angina.