The paper presents the analysis and implementation of a hybrid artificial neural network (ANN) and perturb and observe (P&O) based maximum power point tracking (MPPT) controller designed to enhance the efficiency of photovoltaic systems. Using MATLAB/Simulink for simulations, the study compares the performance of this hybrid approach against traditional MPPT methods, demonstrating superior efficiency under varying environmental conditions. The hybrid ANN-P&O method outperforms both individual techniques in tracking the maximum power point (MPP) efficiently, particularly in rapidly changing solar irradiance scenarios.