The document analyzes the effects of masonry infill walls in reinforced concrete frames on seismic performance, focusing on structures with central openings of 15% and 25%. Utilizing ETABS software, various models were examined, including static and dynamic analyses to assess parameters like base shear, displacement, and story drift. The findings indicate that increased stiffness from infill walls enhances structural resilience, reducing both displacement and story drift during seismic events.